Restorative Dentistry & Endodontics

Research Articles

Do universal adhesives promote bonding to dentin? A systematic review and meta-analysis: Ali A. Elkaffas, Hamdi H. H. Hamama, Salah H. Mahmoud; Restor Dent Endod 2018;43(3):e29. Published online June 18, 2018; DOI: https://doi.org/10.5395/rde.2018.43.e29

Objectives

The aims of this study were to conduct a systematic review of the microtensile bond strength (µTBS) of multi-mode adhesives to dentin and to perform a meta-analysis to assess the significance of differences in the µTBS of one of the most commonly used universal adhesives (Scotchbond Universal, 3M ESPE) depending on whether the etch-and-rinse or self-etch mode was used.

Materials and Methods

An electronic search was performed of MEDLINE/PubMed, ScienceDirect, and EBSCOhost. Laboratory studies that evaluated the µTBS of multi-mode adhesives to dentin using either the etch-and-rinse or self-etch mode were selected. A meta-analysis was conducted of the reviewed studies to quantify the differences in the µTBS of Scotchbond Universal adhesive.

Results

Only 10 studies fulfilled the inclusion criteria for the systematic review. Extensive variation was found in the restorative materials, testing methodologies, and failure mode in the reviewed articles. Furthermore, variation was also observed in the dimensions of the microtensile testing beams. The meta-analysis showed no statistically significant difference between the etch-and-rinse and self-etch modes for Scotchbond Universal adhesive (p > 0.05).

Conclusions

Multi-mode ‘universal’ adhesives can achieve substantial bonding to dentin, regardless of the used modes (either etch-and-rinse or self-etch).

Citations

Citations to this article as recorded by

Influence of Proximal-Cervical Undermined Enamel Areas on Marginal Quality and Enamel Integrity of Laboratory and CAD/CAM Ceramic Inlays and Partial Crowns
Roland Frankenberger, Katharina Friedrich, Marie-Christine Dudek, Julia Winter, Norbert Krämer, Matthias J. Roggendorf
Journal of Functional Biomaterials.2025; 16(3): 82. CrossRef
Improving Bonding Protocols: The Effect of Selective Dentin Etching with Two Different Universal Adhesives—An In Vitro Study
Sandro Ferreira, Tiago Rodrigues, Mariana Nunes, Ana Mano Azul, José João Mendes, Ana Filipa Chasqueira, Joana Costa
Polymers.2025; 17(9): 1215. CrossRef
Effect of surface treatment on glass ionomers in sandwich restorations: a systematic review and meta-analysis of laboratory studies
Hoda S. Ismail, Ashraf Ibrahim Ali, Franklin Garcia-Godoy
Restorative Dentistry & Endodontics.2025; 50(2): e13. CrossRef
Tooth-composite bond failure with a universal and an etch-and-rinse adhesive depending on mode and frequency of application
Ellen Schulz-Kornas, Mathilde Tittel, Hartmut Schneider, Maximilian Bemmann, Marco Pellino, Tobias Meissner, Florian Fuchs, Christian Hannig, Florian Tetschke, Kyung-Jin Park, Michaela Strumpski, Rainer Haak
Dental Materials.2024; 40(2): 359. CrossRef
Comparison of postoperative hypersensitivity between Total-etch and Universal adhesive system: a randomized clinical trial
Kiran Javed, Nouman Noor, Muhammad Zubair Nasir, Manzoor Ahmed Manzoor
Scientific Reports.2024;[Epub] CrossRef
Adhesion and sealing of different universal adhesive systems associated with bulk‐fill resins after using endodontic irrigation solutions: An in vitro study
Érika Mayumi Omoto, Anderson Catelan, Paulo Henrique dos Santos, Luciano Tavares Angelo Cintra, Fernanda de Souza e Silva Ramos, Caio César Pavani, André Luiz Fraga Briso, Ticiane Cestari Fagundes
Australian Endodontic Journal.2024; 50(2): 309. CrossRef
Evaluation of the effects of combined application of dimethylaminohexadecyl methacrylate and MDP on dentin bonding and antimicrobial properties
Jiadi Shen, Ming Ma, Yun Huang, Haochen Miao, Xin Wei
Journal of Materials Science.2023; 58(31): 12685. CrossRef
Efficacy of adhesive strategies for restorative dentistry: A systematic review and network meta-analysis of double-blind randomized controlled trials over 12 months of follow-up
Kevin Sheng-Kai Ma, Li-Tzu Wang, Markus B. Blatz
Journal of Prosthodontic Research.2023; 67(1): 35. CrossRef
Impact of Preceded Tumor Therapeutic Irradiation on the Microtensile Bond Strength of Universal Adhesives Applied in Self-Etch Mode to Human Dentin In Vitro
Sina Broscheit, Dirk Vordermark, Reinhard Gerlach, Christian Ralf Gernhardt
Applied Sciences.2023; 13(13): 7873. CrossRef
Effect of the Adhesive Strategy on Clinical Performance and Marginal Integrity of a Universal Adhesive in Non-Carious Cervical Lesions in a Randomized 36-Month Study
Rainer Haak, Gesa Stache, Hartmut Schneider, Matthias Häfer, Gerhard Schmalz, Ellen Schulz-Kornas
Journal of Clinical Medicine.2023; 12(18): 5776. CrossRef
Universal Adhesives in Clinical Dentistry
Fusun Ozer, Shilpa Patnaikuni
Science, Art and Religion.2023; 2(1--2): 6. CrossRef
Deep proximal margin rebuilding with direct esthetic restorations: a systematic review of marginal adaptation and bond strength
Hoda S. Ismail, Ashraf I. Ali, Rabab El. Mehesen, Jelena Juloski, Franklin Garcia-Godoy, Salah H. Mahmoud
Restorative Dentistry & Endodontics.2022;[Epub] CrossRef
Improving Properties of an Experimental Universal Adhesive by Adding a Multifunctional Dendrimer (G-IEMA): Bond Strength and Nanoleakage Evaluation
Joana Vasconcelos e Cruz, António H. S. Delgado, Samuel Félix, José Brito, Luísa Gonçalves, Mário Polido
Polymers.2022; 14(7): 1462. CrossRef
Scoping review of trials evaluating adhesive strategies in pediatric dentistry: where do simplified strategies lie?
António H. S. Delgado, Hasan Jamal, Anne Young, Paul Ashley
BMC Oral Health.2021;[Epub] CrossRef
Does acid etching prior to applying universal adhesives affect the bond strength of glass fiber post to root dentin?
Helder Callegaro Velho, Eduardo Trindade Dalence, Pablo Soares Machado, Marília Pivetta Rippe, Jovito Adiel Skupien, Vinícius Felipe Wandscher
International Journal of Adhesion and Adhesives.2021; 105: 102795. CrossRef
Does Adhesive Layer Thickness and Tag Length Influence Short/Long-Term Bond Strength of Universal Adhesive Systems? An In-Vitro Study
Naji Kharouf, Tarek Ashi, Ammar Eid, Levi Maguina, Jihed Zghal, Nairy Sekayan, Rim Bourgi, Louis Hardan, Salvatore Sauro, Youssef Haikel, Davide Mancino
Applied Sciences.2021; 11(6): 2635. CrossRef
Chronological history and current advancements of dental adhesive systems development: a narrative review
Maicon Sebold, Carolina Bosso André, Beatriz Ometto Sahadi, Lorenzo Breschi, Marcelo Giannini
Journal of Adhesion Science and Technology.2021; 35(18): 1941. CrossRef
Laboratory methods for measuring adhesive bond strength between restoration materials and hard tooth tissues
I.Ya. Poyurovskaya, A.P. Polikarpova, F.S. Rusanov
Stomatologiya.2021; 100(5): 88. CrossRef
Effect of Curcumin Suspension and Vitamin C on Dentin Shear Bond Strength and Durability. A Pilot Study
Dalia A. Abuelenain, Ensanya A. Abou Neel, Tariq S. Abuhaimed, Amal M. Alamri, Hanan S. Ammar, Sahar M. N. Bukhary
The Open Dentistry Journal.2021; 15(1): 540. CrossRef
Effect of 9.3 μm CO2 and 2.94 μm Er:YAG Laser vs. Bur Preparations on Marginal Adaptation in Enamel and Dentin of Mixed Class V Cavities Restored With Different Restorative Systems
Clara Isabel Anton y Otero, Enrico Di Bella, Ivo Krejci, Tissiana Bortolotto
Frontiers in Dental Medicine.2021;[Epub] CrossRef
Adhesion strategy and curing mode of a universal adhesive influence the bonding of dual-cured core build-up resin composite to dentin
Ahmed Eid Elsayed, Mohamed Amr Kamel, Farid Sabry El-Askary
Journal of Adhesion Science and Technology.2021; 35(1): 52. CrossRef
Influence of etching mode and composite resin type on bond strength to dentin using universal adhesive system
Stefan Dačić, Milan Miljković, Aleksandar Mitić, Goran Radenković, Marija Anđelković‐Apostolović, Milica Jovanović
Microscopy Research and Technique.2021; 84(6): 1212. CrossRef
Universal adhesives - a new direction in the development of adhesive systems
A. Tichý, K. Hosaka, J. Tagami
Česká stomatologie a praktické zubní lékařství.2020; 120(1): 4. CrossRef
Effect of Over-Etching and Prolonged Application Time of a Universal Adhesive on Dentin Bond Strength
Phoebe Burrer, Hoang Dang, Matej Par, Thomas Attin, Tobias T. Tauböck
Polymers.2020; 12(12): 2902. CrossRef
Profile of a 10-MDP-based universal adhesive system associated with chlorhexidine: Dentin bond strength and in situ zymography performance
Marina Ciccone Giacomini, Polliana Mendes Candia Scaffa, Rafael Simões Gonçalves, Giovanna Speranza Zabeu, Cristina de Mattos Pimenta Vidal, Marcela Rocha de Oliveira Carrilho, Heitor Marques Honório, Linda Wang
Journal of the Mechanical Behavior of Biomedical Materials.2020; 110: 103925. CrossRef
Universal dental adhesives: Current status, laboratory testing, and clinical performance
Sanket Nagarkar, Nicole Theis‐Mahon, Jorge Perdigão
Journal of Biomedical Materials Research Part B: Applied Biomaterials.2019; 107(6): 2121. CrossRef
Modifying Adhesive Materials to Improve the Longevity of Resinous Restorations
Wen Zhou, Shiyu Liu, Xuedong Zhou, Matthias Hannig, Stefan Rupf, Jin Feng, Xian Peng, Lei Cheng
International Journal of Molecular Sciences.2019; 20(3): 723. CrossRef

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Effects of solvent volatilization time on the bond strength of etch-and-rinse adhesive to dentin using conventional or deproteinization bonding techniques: José Aginaldo de Sousa Júnior, Márcia Luciana Carregosa Santana, Fabricio Eneas Diniz de Figueiredo, André Luis Faria-e-Silva; Restor Dent Endod 2015;40(3):202-208. Published online March 17, 2015; DOI: https://doi.org/10.5395/rde.2015.40.3.202

Abstract PDF PubReader ePub

Objectives

This study determined the effect of the air-stream application time and the bonding technique on the dentin bond strength of adhesives with different solvents. Furthermore, the content and volatilization rate of the solvents contained in the adhesives were also evaluated.

Materials and Methods

Three adhesive systems with different solvents (Stae, SDI, acetone; XP Bond, Dentsply De Trey, butanol; Ambar, FGM, ethanol) were evaluated. The concentrations and evaporation rates of each adhesive were measured using an analytical balance. After acid-etching and rinsing, medium occlusal dentin surfaces of human molars were kept moist (conventional) or were treated with 10% sodium hypochlorite for deproteinization. After applying adhesives over the dentin, slight air-stream was applied for 10, 30 or 60 sec. Composite cylinders were built up and submitted to shear testing. The data were submitted to ANOVA and Tukey's test (α = 0.05).

Results

Stae showed the highest solvent content and Ambar the lowest. Acetone presented the highest evaporation rate, followed by butanol. Shear bond strengths were significantly affected only by the factors of 'adhesive' and 'bonding technique' (p < 0.05), while the factor 'duration of air-stream' was not significant. Deproteinization of dentin increased the bond strength (p < 0.05). Stae showed the lowest bond strength values (p < 0.05), while no significant difference was observed between XP Bond and Ambar.

Conclusions

Despite the differences in content and evaporation rate of the solvents, the duration of air-stream application did not affect the bond strength to dentin irrespective of the bonding technique.

Citations

Citations to this article as recorded by

Effect of adhesive air-drying time on bond strength to dentin: A systematic review and meta-analysis
Mohamed M. Awad, Ali Alrahlah, Jukka P. Matinlinna, Hamdi Hosni Hamama
International Journal of Adhesion and Adhesives.2019; 90: 154. CrossRef

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Original Article

Effect of dentinal tubules orientation on penetration pattern of dentin adhesives using confocal laser scanning microscopy: Dong-Jun Kim, Yun-Chan Hwang, Sun-Ho Kim, Won-Mann Oh, In-Nam Hwang; J Korean Acad Conserv Dent 2003;28(5):392-401. Published online September 30, 2003; DOI: https://doi.org/10.5395/JKACD.2003.28.5.392

Abstract PDF PubReader ePub

The purpose of this study was to evaluate the penetration pattern of dentin adhesives according to the orientation of dentinal tubules with confocal laser scanning microscopy. Specimens having perpendicular, parallel and oblique surface to dentinal tubules were fabricated. The primer of dentin adhesives (ALL BOND® 2, CLEARFIL™ SE BOND and PQ1) was mixed with fluorescent material, rhodamine B isothiocyanate (Aldrich Chem. CO., Milw., USA). It was applied to the specimens according to the instructions of manufactures. The specimens were covered with composite resin (Estelite, shade A2) and then cut to a thickness of 500 µm with low speed saw (Isomet™, Buehler, USA). The adhesive pattern of dentin adhesives were observed by fluorescence image using confocal laser scanning microscopy.

The results were as follows.

For the groups with tubules perpendicular to bonded surface, funnel shape of resin tag was observed in all specimen. However, resin tags were more prominent in phosphoric acid etching system (ALL BOND® 2 and PQ1) than self etching system (CLEARFIL™ SE BOND).

For the groups with tubules parallel to bonded surface, rhodamine-labeled primer penetrated into peritubular dentin parallel to the orientation of dentinal tubules. But rhodamine-labeled primer of PQ1 diffused more radially into surrounding intertubular dentin than other dentin adhesive systems.

For the groups with tubules oblique to bonded surface, resin tags appeared irregular and discontinuous. But they penetrated deeper into dentinal tubules than other groups.

Citations

Citations to this article as recorded by

Bonding efficacy of cured or uncured dentin adhesives in indirect resin
Ji-Hyun Jang, Bin-Na Lee, Hoon-Sang Chang, Yun-Chan Hwang, Won-Mann Oh, In-Nam Hwang
Journal of Korean Academy of Conservative Dentistry.2011; 36(6): 490. CrossRef

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