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  • Review Article
    Silver nanoparticles in endodontics: recent developments and applications
    Aysenur Oncu, Yan Huang, Gulin Amasya, Fatma Semra Sevimay, Kaan Orhan, Berkan Celikten
    Restor Dent Endod 2021;46(3):e38.   Published online July 1, 2021
    DOI: https://doi.org/10.5395/rde.2021.46.e38
    AbstractAbstract PDFPubReaderePub

    The elimination of endodontic biofilms and the maintenance of a leak-proof canal filling are key aspects of successful root canal treatment. Several materials have been introduced to treat endodontic disease, although treatment success is limited by the features of the biomaterials used. Silver nanoparticles (AgNPs) have been increasingly considered in dental applications, especially endodontics, due to their high antimicrobial activity. For the present study, an electronic search was conducted using MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar, and EMBASE. This review provides insights into the unique characteristics of AgNPs, including their chemical, physical, and antimicrobial properties; limitations; and potential uses. Various studies involving different application methods of AgNPs were carefully examined. Based on previous clinical studies, the synthesis, means of obtaining, usage conditions, and potential cytotoxicity of AgNPs were evaluated. The findings indicate that AgNPs are effective antimicrobial agents for the elimination of endodontic biofilms.

    Citations

    Citations to this article as recorded by  
    • Scoping review on the genotoxicity of silver nanoparticles in endodontics: therapeutic saviors or genetic saboteurs?
      Galvin Sim Siang Lin, Widya Lestari, Mohd Haikal Muhamad Halil, Mohd Syafiq Abd Aziz
      Odontology.2025; 113(2): 457.     CrossRef
    • Bioceramics in Endodontics: Limitations and Future Innovations—A Review
      Peramune Arachchilage Amila Saman Prasad Kumara, Paul Roy Cooper, Peter Cathro, Maree Gould, George Dias, Jithendra Ratnayake
      Dentistry Journal.2025; 13(4): 157.     CrossRef
    • Recent advances in antibacterial nanoformulations for endodontic applications
      Tiago Dionísio, Pedro Brandão, Vanessa Machado, João Botelho, José João Mendes, Pedro Fonte
      Expert Opinion on Drug Delivery.2025; : 1.     CrossRef
    • Systematic review of silver and vanadium-based antibiofilm agents: mechanisms and efficacy in oral biofilms
      João Marcos Carvalho-Silva, Andréa Cândido dos Reis
      Future Microbiology.2025; 20(10): 639.     CrossRef
    • Antimicrobial Effects of Formulations of Various Nanoparticles and Calcium Hydroxide as Intra-canal Medications Against Enterococcus faecalis: A Systematic Review
      Seema H Bukhari, Dax Abraham, Shakila Mahesh
      Cureus.2024;[Epub]     CrossRef
    • The Push-Out Bond Strength, Surface Roughness, and Antimicrobial Properties of Endodontic Bioceramic Sealers Supplemented with Silver Nanoparticles
      Karla Navarrete-Olvera, Nereyda Niño-Martínez, Idania De Alba-Montero, Nuria Patiño-Marín, Facundo Ruiz, Horacio Bach, Gabriel-Alejandro Martínez-Castañón
      Molecules.2024; 29(18): 4422.     CrossRef
    • Synergistic bactericidal activity of chlorhexidine loaded on positively charged ionic liquid-protected silver nanoparticles as a root canal disinfectant against Enterococcus faecalis: An ex vivo study
      Abbas Abbaszadegan, Elham Tayebikhorami, Ahmad Gholami, Nazanin Bonyanpour, Bahar Asheghi, Sara Nikmanesh
      Journal of Ionic Liquids.2024; 4(2): 100117.     CrossRef
    • Improving the Antimicrobial Potency of Berberine for Endodontic Canal Irrigation Using Polymeric Nanoparticles
      Célia Marques, Liliana Grenho, Maria Helena Fernandes, Sofia A. Costa Lima
      Pharmaceutics.2024; 16(6): 786.     CrossRef
    • A narrative review on application of metal and metal oxide nanoparticles in endodontics
      Roohollah Sharifi, Ahmad Vatani, Amir Sabzi, Mohsen Safaei
      Heliyon.2024; 10(15): e34673.     CrossRef
    • The Effectiveness of Silver Nanoparticles Mixed with Calcium Hydroxide against Candida albicans: An Ex Vivo Analysis
      Maha Alghofaily, Jood Alfraih, Aljohara Alsaud, Norah Almazrua, Terrence S. Sumague, Sayed H. Auda, Fahd Alsalleeh
      Microorganisms.2024; 12(2): 289.     CrossRef
    • Evaluation of the efficacy of a novel disinfecting material on the surface topography of gutta-percha: An in vitro study
      KHanisha Reddy, Lekshmi Chandran, TMurali Mohan, K Sudha, DL Malini, Bonney Dominic
      Journal of Conservative Dentistry.2023; 26(1): 94.     CrossRef
    • Silver Nanoparticles and Their Therapeutic Applications in Endodontics: A Narrative Review
      Farzaneh Afkhami, Parisa Forghan, James L. Gutmann, Anil Kishen
      Pharmaceutics.2023; 15(3): 715.     CrossRef
    • Nanopartículas antimicrobianas en endodoncia: Revisión narrativa
      Gustavo Adolfo Tovar Rangel , Fanny Mildred González Sáenz , Ingrid Ximena Zamora Córdoba , Lina María García Zapata
      Revista Estomatología.2023;[Epub]     CrossRef
    • Functionalized Nanoparticles: A Paradigm Shift in Regenerative Endodontic Procedures
      Vinoo Subramaniam Ramachandran, Mensudar Radhakrishnan, Malathi Balaraman Ravindrran, Venkatesh Alagarsamy, Gowri Shankar Palanisamy
      Cureus.2022;[Epub]     CrossRef
    • 1,708 View
    • 36 Download
    • 12 Web of Science
    • 14 Crossref
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    Research Article
    Micro-computed tomographic assessment of the shaping ability of the One Curve, One Shape, and ProTaper Next nickel-titanium rotary systems
    Pelin Tufenkci, Kaan Orhan, Berkan Celikten, Burak Bilecenoglu, Gurkan Gur, Semra Sevimay
    Restor Dent Endod 2020;45(3):e30.   Published online May 22, 2020
    DOI: https://doi.org/10.5395/rde.2020.45.e30
    AbstractAbstract PDFPubReaderePub
    Objectives

    This micro-computed tomographic (CT) study aimed to compare the shaping abilities of ProTaper Next (PTN), One Shape (OS), and One Curve (OC) files in 3-dimensionally (3D)-printed mandibular molars.

    Materials and Methods

    In order to ensure standardization, 3D-printed mandibular molars with a consistent mesiobuccal canal curvature (45°) were used in the present study (n = 18). Specimens were instrumented with the OC, OS, or PTN files. The teeth were scanned pre- and post-instrumentation using micro-CT to detect changes of the canal volume and surface area, as well as to quantify transportation of the canals after instrumentation. Two-way analysis of variance was used for statistical comparisons.

    Results

    No statistically significant differences were found between the OC and OS groups in the changes of the canal volume and surface area before and after instrumentation (p > 0.05). The OC files showed significantly less transportation than the OS or PTN systems for the apical section (p < 0.05). In a comparison of the systems, similar values were found at the coronal and middle levels, without any significant differences (p > 0.05).

    Conclusions

    These 3 instrumentation systems showed similar shaping abilities, although the OC file achieved a lesser extent of transportation in the apical zone than the OS and PTN files. All 3 file systems were confirmed to be safe for use in mandibular mesial canals.

    Citations

    Citations to this article as recorded by  
    • Effect of different kinematics and perforation diameter on integrated electronic apex locator accuracy in detecting root canal perforations
      Ecenur Tuzcu, Safa Kurnaz
      European Journal of Oral Sciences.2025;[Epub]     CrossRef
    • A Comparative Evaluation of the Efficiencies of Different Rotary File Systems in Terms of Remaining Dentin Thickness Using Cone Beam Computed Tomography: An In Vitro Study
      Vivek P Vadera , Sandhya K Punia, Saleem D Makandar, Rahul Bhargava, Pradeep Bapna
      Cureus.2024;[Epub]     CrossRef
    • Comparison of Different Rotary Nickel–titanium Systems to Evaluate Coronal Leakage of Root Canals: An in Vitro Study
      Rasha M. Al-Shamaa
      Dental Hypotheses.2023; 14(3): 81.     CrossRef
    • Comparative evaluation of canal transportation and canal centering ability in oval canals with newer nickel–titanium rotary single file systems – A cone-beam computed tomography study
      SimarKaur Manocha, SuparnaGanguly Saha, RollyS Agarwal, Neelam Vijaywargiya, MainakKanti Saha, Anjali Surana
      Journal of Conservative Dentistry.2023; 26(3): 326.     CrossRef
    • Accumulated Hard Tissue Debris and Root Canal Shaping Profiles Following Instrumentation with Gentlefile, One Curve, and Reciproc Blue
      Chi Wai Chan, Virginia Rosy Romeo, Angeline Lee, Chengfei Zhang, Prasanna Neelakantan, Eugenio Pedullà
      Journal of Endodontics.2023; 49(10): 1344.     CrossRef
    • Comparative evaluation of canal transportation and centering ability of rotary and reciprocating file systems using cone-beam computed tomography: An in vitro study
      Tanisha Singh, Manju Kumari, Rohit Kochhar
      Journal of Conservative Dentistry.2023; 26(3): 332.     CrossRef
    • Retreatability of Bioceramic Sealer Using One Curve Rotary File Assessed by Microcomputed Tomography
      Dina G Mufti, Saad A Al-Nazhan
      The Journal of Contemporary Dental Practice.2022; 22(10): 1175.     CrossRef
    • Micro-computed tomography in preventive and restorative dental research: A review
      Mehrsima Ghavami-Lahiji, Reza Tayefeh Davalloo, Gelareh Tajziehchi, Paria Shams
      Imaging Science in Dentistry.2021; 51(4): 341.     CrossRef
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    • 5 Download
    • 8 Crossref
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