Restorative Dentistry & Endodontics

Research Articles

Cleaning protocols to enhance bond strength of fiberglass posts on root canals filled with bioceramic sealer: an in vitro comparative study: Thiago Bessa Marconato Antunes, Juliana Delatorre Bronzato, Joice Graciani, Ana Cristina Padilha Janini, Rocharles Cavalcante Fontenele, Francisco Haiter Neto, Brenda Paula Figueiredo de Almeida Gomes, Marina Angélica Marciano da Silva; Restor Dent Endod 2025;50(2):e20. Published online May 21, 2025; DOI: https://doi.org/10.5395/rde.2025.50.e20

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This study aimed to evaluate whether the agitation protocols using ultrasonic inserts or the XP-endo Finisher R file improved the removal of two different endodontic sealer remnants and the bond strength of fiberglass posts to dentin.
Methods
Seventy-two human teeth were selected. The canals were prepared with Reciproc 50 and Easy ProDesign 30/.10 and root filled according to the endodontic sealer groups: AH Plus or EndoSequence BC Sealer HiFlow. The samples were kept at 37ºC and 95% humidity for 28 days. During the post space preparation, the obturation was removed with Largo burs, and the groups were divided according to the irrigant agitation protocols (n = 12): no agitation, agitation with R1-Clearsonic associated with E1-Irrisonic ultrasonic inserts, or agitation with XP-endo Finisher R file. The fiberglass posts were cemented with RelyX ARC. The roots were sectioned into slices and submitted to the push-out test. Micro-computed tomography analysis was used to check the effectiveness of irrigating solution agitation in the elimination of remnants.
Results
The cleaning protocols with agitation were more effective in increasing the bond strength of posts to dentin for both sealer groups compared to non-agitation (p < 0.05). There was no difference between the same cleaning protocols for the different sealers. Among the different thirds, there was no statistical difference for the same sealer in the different cleaning protocols (p > 0.05).
Conclusions
Both agitation protocols effectively clean root-filled canals sealed with resin-based and calcium silicate-based sealers during fiberglass post space preparation. These protocols result in improved bond strength compared to non-agitation methods.

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Nanoleakage of apical sealing using a calcium silicate-based sealer according to canal drying methods: Yoon-Joo Lee, Kyung-Mo Cho, Se-Hee Park, Yoon Lee, Jin-Woo Kim; Restor Dent Endod 2024;49(2):e20. Published online April 19, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e20

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This study investigated the nanoleakage of root canal obturations using calcium silicate-based sealer according to different drying methods.
Materials and Methods
Fifty-two extracted mandibular premolars with a single root canal and straight root were selected for this study. After canal preparation with a nickel-titanium rotary file system, the specimens were randomly divided into 4 groups according to canal drying methods (1: complete drying, 2: blot drying/distilled water, 3: blot drying/NaOCl, 4: aspiration only). The root canals were obturated using a single-cone filling technique with a calcium silicate–based sealer. Nanoleakage was evaluated using a nanoflow device after 24 hours, 1 week, and 1 month. Data were collected twice per second at the nanoscale and measured in nanoliters per second. Data were statistically analyzed using the Kruskal-Wallis and Mann–Whitney U-tests (p < 0.05).
Results
The mean flow rate measured after 24 hours showed the highest value among the time periods in all groups. However, the difference in the flow rate between 1 week and 1 month was not significant. The mean flow rate of the complete drying group was the highest at all time points. After 1 month, the mean flow rate in the blot drying group and the aspiration group was not significantly different.
Conclusions
Within the limitations of this study, the canal drying method had a significant effect on leakage and sealing ability in root canal obturations using a calcium silicate-based sealer. Thus, a proper drying procedure is critical in endodontic treatment.

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A scientometric, bibliometric, and thematic map analysis of hydraulic calcium silicate root canal sealers: Anastasios Katakidis, Konstantinos Kodonas, Anastasia Fardi, Christos Gogos; Restor Dent Endod 2023;48(4):e41. Published online November 13, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e41

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Objectives

This scientometric and bibliometric analysis explored scientific publications related to hydraulic calcium silicate-based (HCSB) sealers used in endodontology, aiming to describe basic bibliometric indicators and analyze current research trends.

Materials and Methods

A comprehensive search was conducted in Web of Science and Scopus using specific HCSB sealer and general endodontic-related terms. Basic research parameters were collected, including publication year, authorship, countries, institutions, journals, level of evidence, study design and topic of interest, title terms, author keywords, citation counts, and density.

Results

In total, 498 articles published in 136 journals were retrieved for the period 2008–2023. Brazil was the leading country, and the universities of Bologna in Italy and Sao Paolo in Brazil were represented equally as leading institutions. The most frequently occurring keywords were “calcium silicate,” “root canal sealer MTA-Fillapex,” and “biocompatibility,” while title terms such as “calcium,” “sealers,” “root,” “canal,” “silicate based,” and “endodontic” occurred most often. According to the thematic map analysis, “solubility” appeared as a basic theme of concentrated research interest, and “single-cone technique” was identified as an emerging, inadequately developed theme. The co-occurrence analysis revealed 4 major clusters centered on sealers’ biological and physicochemical properties, obturation techniques, retreatability, and adhesion.

Conclusions

This analysis presents bibliographic features and outlines changing trends in HCSB sealer research. The research output is dominated by basic science articles scrutinizing the biological and specific physicochemical properties of commonly used HCSB sealers. Future research needs to be guided by studies with a high level of evidence that utilize innovative, sophisticated technologies.

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Agri-Food Sector: Contemporary Trends, Possible Gaps, and Prospective Directions
José Roberto Herrera Cantorani, Meire Ramalho de Oliveira, Luiz Alberto Pilatti, Thales Botelho de Sousa
Metrics.2025; 2(1): 3. CrossRef
Scientific mapping of experimental research on solar cookers: Global trends, evolution, and future directions
Flavio Odoi-Yorke, Bismark Baah, Richard Opoku
Solar Energy Advances.2025; 5: 100093. CrossRef
Bibliometric analysis of the GentleWave system: trends, collaborations, and research gaps
Raimundo Sales de Oliveira Neto, Thais de Moraes Souza, João Vitor Oliveira de Amorim, Thaine Oliveira Lima, Guilherme Ferreira da Silva, Rodrigo Ricci Vivan, Murilo Priori Alcalde, Marco Antonio Hungaro Duarte
Restorative Dentistry & Endodontics.2025; 50(2): e17. CrossRef
A bibliometric analysis of global research trend and progress on Dy doped materials
Sangeeta Kadyan, Manju Nain, Ashima Makhija, Poonam Punia, Anil Ohlan, Sajjan Dahiya, R. Punia, A.S. Maan
Journal of Alloys and Compounds Communications.2024; 3: 100006. CrossRef
Comparative bioactivity and immunomodulatory potential of the new Bioroot Flow and AH Plus Bioceramic sealer: An in vitro study on hPDLSCs
José Luis Sanz, Sergio López-García, David García-Bernal, Francisco Javier Rodríguez-Lozano, Leopoldo Forner, Adrián Lozano, Laura Murcia
Clinical Oral Investigations.2024;[Epub] CrossRef
Analyzing collaboration and impact: A bibliometric review of four highly published authors’ research profiles on collaborative maps
Willy Chou, Julie Chi Chow
Medicine.2024; 103(28): e38686. CrossRef

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Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis: Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura; Restor Dent Endod 2023;48(2):e21. Published online May 5, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e21

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Objectives

This study evaluated the effects of Biodentine (BD), Bio-C Repair (BCR), and mineral trioxide aggregate (MTA) plug on the fracture resistance of simulated immature teeth with replacement root resorption (RRR) and in vitro-induced osteoclastogenesis.

Materials and Methods

Sixty bovine incisors simulating immature teeth and RRR were divided into 5 groups: BD and BCR groups, with samples completely filled with the respective materials; MTA group, which utilized a 3-mm apical MTA plug; RRR group, which received no root canal filling; and normal periodontal ligament (PL) group, which had no RRR and no root canal filling. All the teeth underwent cycling loading, and compression strength testing was performed using a universal testing machine. RAW 264.7 macrophages were treated with 1:16 extracts of BD, BCR, and MTA containing receptor activator of nuclear factor-kappa B ligand (RANKL) for 5 days. RANKL-induced osteoclast differentiation was assessed by staining with tartrate-resistant acid phosphatase. The fracture load and osteoclast number were analyzed using 1-way ANOVA and Tukey’s test (α = 0.05).

Results

No significant difference in fracture resistance was observed among the groups (p > 0.05). All materials similarly inhibited osteoclastogenesis (p > 0.05), except for BCR, which led to a lower percentage of osteoclasts than did MTA (p < 0.0001).

Conclusions

The treatment options for non-vital immature teeth with RRR did not strengthen the teeth and promoted a similar resistance to fractures in all cases. BD, MTA, and BCR showed inhibitory effects on osteoclast differentiation, with BCR yielding improved results compared to the other materials.

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In vitro comparison of fracture strength of maxillary incisors with the simulated external root resorption cavities repaired with BioMTA or Biodentine
Tufan Ozasir, Birgul Ozasir, Nagihan Aribal, Derin Bugu Yuzer, Baris Kandemir, Kamran Gulsahi
Journal of Dental Sciences.2025; 20(3): 1532. CrossRef
Comparative Analysis of Gene Expression in Periodontal Ligament Stem Cells Exposed to Biodentine and Bio-C Repair: Implications for Cementogenesis—An In Vitro Study
Mahmoud M. Bakr, Mahmoud Al Ankily, Mohammed Meer, Mohamed Shamel
Oral.2025; 5(1): 19. CrossRef
Evaluation of Different Techniques and Materials for Filling in 3-dimensional Printed Teeth Replicas with Perforating Internal Resorption by Means of Micro–Computed Tomography
Angelo J.S. Torres-Carrillo, Helena C. Assis, Rodrigo E. Salazar-Gamarra, Leonardo Moreira Teodosio, Alice C. Silva-Sousa, Jardel F. Mazzi-Chaves, Priscila B. Ferreira-Soares, Manoel D. Sousa-Neto, Fabiane C. Lopes-Olhê
Journal of Endodontics.2024; 50(2): 205. CrossRef

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Effects of calcium silicate cements on neuronal conductivity: Derya Deniz-Sungur, Mehmet Ali Onur, Esin Akbay, Gamze Tan, Fügen Daglı-Comert, Taner Cem Sayın; Restor Dent Endod 2022;47(2):e18. Published online March 7, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e18

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This study evaluated alterations in neuronal conductivity related to calcium silicate cements (CSCs) by investigating compound action potentials (cAPs) in rat sciatic nerves.
Materials and Methods
Sciatic nerves were placed in a Tyrode bath and cAPs were recorded before, during, and after the application of test materials for 60-minute control, application, and recovery measurements, respectively. Freshly prepared ProRoot MTA, MTA Angelus, Biodentine, Endosequence RRM-Putty, BioAggregate, and RetroMTA were directly applied onto the nerves. Biopac LabPro version 3.7 was used to record and analyze cAPs. The data were statistically analyzed.
Results
None of the CSCs totally blocked cAPs. RetroMTA, Biodentine, and MTA Angelus caused no significant alteration in cAPs (p > 0.05). Significantly lower cAPs were observed in recovery measurements for BioAggregate than in the control condition (p < 0.05). ProRoot MTA significantly but transiently reduced cAPs in the application period compared to the control period (p < 0.05). Endosequence RRM-Putty significantly reduced cAPs.
Conclusions
Various CSCs may alter cAPs to some extent, but none of the CSCs irreversibly blocked them. The usage of fast-setting CSCs during apexification or regeneration of immature teeth seems safer than slow-setting CSCs due to their more favorable neuronal effects.

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Comparative analysis of bond strength to root dentin and compression of bioceramic cements used in regenerative endodontic procedures: Maykely Naara Morais Rodrigues, Kely Firmino Bruno, Ana Helena Gonçalves de Alencar, Julyana Dumas Santos Silva, Patrícia Correia de Siqueira, Daniel de Almeida Decurcio, Carlos Estrela; Restor Dent Endod 2021;46(4):e59. Published online November 9, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e59

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Objectives

This study compared the Biodentine, MTA Repair HP, and Bio-C Repair bioceramics in terms of bond strength to dentin, failure mode, and compression.

Materials and Methods

Fifty-four slices obtained from the cervical third of 18 single-rooted human mandibular premolars were randomly distributed (n = 18). After insertion of the bioceramic materials, the push-out test was performed. The failure mode was analyzed using stereomicroscopy. Another set of cylindrically-shaped bioceramic samples (n = 10) was prepared for compressive strength testing. The normality of data distribution was analyzed using the Shapiro-Wilk test. The Kruskal-Wallis and Friedman tests were used for the push-out test data, while compressive strength was analyzed with analysis of variance and the Tukey test, considering a significance level of 0.05.

Results

Biodentine presented a higher median bond strength value (14.79 MPa) than MTA Repair HP (8.84 MPa) and Bio-C Repair (3.48 MPa), with a significant difference only between Biodentine and Bio-C Repair. In the Biodentine group, the most frequent failure mode was mixed (61%), while in the MTA Repair HP and Bio-C Repair groups, it was adhesive (94% and 72%, respectively). Biodentine showed greater resistance to compression (29.59 ± 8.47 MPa) than MTA Repair HP (18.68 ± 7.40 MPa) and Bio-C Repair (19.96 ± 3.96 MPa) (p < 0.05).

Conclusions

Biodentine showed greater compressive strength than MTA Repair HP and Bio-C Repair, and greater bond strength than Bio-C Repair. The most frequent failure mode of Biodentine was mixed, while that of MTA Repair HP and Bio-C Repair was adhesive.

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Comparación de la resistencia compresiva entre el Agregado Trióxido Mineral y BiodentineTM en perforaciones de furca de molares inferiores permanentes
Jheymy Gerardo Huatuco-Granda, John Paul Torres-Navarro, Rosa Josefina Roncal-Espinoza
Revista Facultad de Odontología.2024;[Epub] CrossRef
Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis
Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura
Restorative Dentistry & Endodontics.2023;[Epub] CrossRef
Evaluation the Marginal Adaptation for the Bio C Repair and Other Root end Filling Material by Using Scanning Electron Microscope (A Comparative In Vitro Study)
Fatimah HAMADHİ, Zainab M.
Cumhuriyet Dental Journal.2023; 26(3): 261. CrossRef
Dentin Bond Strength of Calcium Silicate-Based Materials: A Systematic Review of In Vitro Studies
Natalia Radulica, José Luis Sanz, Adrián Lozano
Applied Sciences.2023; 14(1): 104. CrossRef
Evaluation Of The Push-out Bond Strength Of The Bio-C Repair And Compare It With The Mineral Trioxide Aggregate And Amalgam When Used As Root-end Filling Material
Fatimah R. Hammadi, Zainab M Abdul-Ameer
Dental Hypotheses.2023; 14(2): 62. CrossRef
Effect of different root canal irrigants on push-out bond strength of two novel root-end filling materials
Nada Omar, Rasha M. Abdelraouf, Tamer M. Hamdy
BMC Oral Health.2023;[Epub] CrossRef
Effect of irrigation systems on the bond strength of calcium-silicate-based cement used as pulp barrier in regenerative endodontic treatment
Cihan Hascizmeci, Burak Buldur
Journal of Adhesion Science and Technology.2023; 37(23): 3393. CrossRef

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Push-out bond strength and marginal adaptation of apical plugs with bioactive endodontic cements in simulated immature teeth: Maria Aparecida Barbosa de Sá, Eduardo Nunes, Alberto Nogueira da Gama Antunes, Manoel Brito Júnior, Martinho Campolina Rebello Horta, Rodrigo Rodrigues Amaral, Stephen Cohen, Frank Ferreira Silveira; Restor Dent Endod 2021;46(4):e53. Published online October 20, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e53

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Objectives

This study evaluates the bond strength and marginal adaptation of mineral trioxide aggregate (MTA) Repair HP and Biodentine used as apical plugs; MTA was used as reference material for comparison.

Materials and Methods

A total of 30 single-rooted teeth with standardized, artificially created open apices were randomly divided into 3 groups (n = 10 per group), according to the material used to form 6-mm-thick apical plugs: group 1 (MTA Repair HP); group 2 (Biodentine); and group 3 (white MTA). Subsequently, the specimens were transversely sectioned to obtain 2 (cervical and apical) 2.5-mm-thick slices per root. Epoxy resin replicas were observed under a scanning electron microscope to measure the gap size at the material/dentin interface (the largest and smaller gaps were recorded for each replica). The bond strength of the investigated materials to dentin was determined using the push-out test. The variable bond strengths and gap sizes were evaluated independently at the apical and cervical root dentin slices. Data were analyzed using descriptive and analytic statistics.

Results

The comparison between the groups regarding the variables' bond strengths and gap sizes showed no statistical difference (p > 0.05) except for a single difference in the smallest gap at the cervical root dentin slice, which was higher in group 3 than in group 1 (p < 0.05).

Conclusions

The bond strength and marginal adaptation to root canal walls of MTA HP and Biodentine cement were comparable to white MTA.

Citations

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Evaluation of the root dentin bond strength and intratubular biomineralization of a premixed calcium aluminate-based hydraulic bioceramic endodontic sealer
Yu-Na Lee, Min-Kyeong Kim, Hee-Jin Kim, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min
Journal of Oral Science.2024; 66(2): 96. CrossRef
Managing Cracked Teeth with Root Extension: A Prospective Preliminary Study Using Biodentine™ Material
Kênia Maria Soares de Toubes, Isabella Sousa Corrêa, Regina Célia Lopes Valadares, Stephanie Quadros Tonelli, Fábio Fernandes Borém Bruzinga, Frank Ferreira Silveira, Dr Karthikeyan Ramalingam
International Journal of Dentistry.2024;[Epub] CrossRef
Marginal adaptation of customized gutta percha cone with calcium silicate based sealer versus MTA and biodentine apical plugs in simulated immature permanent teeth (an in vitro study)
Mary M. Mina, Sybel M. Moussa, Mahmoud R. Aboelseoud
BMC Oral Health.2024;[Epub] CrossRef
Comparative Evaluation of Push-Out Bond Strength of Conventional Mineral Trioxide Aggregate, Biodentine, a Modified Mineral Trioxide Aggregate, and Two Novel Antibacterial-Enhanced Mineral Trioxide Aggregates
Arokia Rajkumar Shancy Merlin, Vignesh Ravindran, Ganesh Jeevanandan, Rajalakshmanan Eswaramoorthy, Abirami Arthanari
Cureus.2024;[Epub] CrossRef
Push out bond strength of hydraulic cements used at different thicknesses
C. Ruiz Durán, Dra L. Gancedo-Caravia, V. Vera González, C. González Losada
BMC Oral Health.2023;[Epub] CrossRef
Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis
Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura
Restorative Dentistry & Endodontics.2023;[Epub] CrossRef

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Micro-computed tomographic evaluation of single-cone obturation with three sealers: Sahar Zare, Ivy Shen, Qiang Zhu, Chul Ahn, Carolyn Primus, Takashi Komabayashi; Restor Dent Endod 2021;46(2):e25. Published online April 16, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e25

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Objectives

This study used micro-computed tomography (µCT) to compare voids and interfaces in single-cone obturation among AH Plus, EndoSequence BC, and prototype surface pre-reacted glass ionomer (S-PRG) sealers and to determine the percentage of sealer contact at the dentin and gutta-percha (GP) interfaces.

Materials and Methods

Fifteen single-rooted human teeth were shaped using ProTaper NEXT size X5 rotary files using 2.5% NaOCl irrigation. Roots were obturated with a single-cone ProTaper NEXT GP point X5 with AH Plus, EndoSequence BC, or prototype S-PRG sealer (n = 5/group).

Results

The volumes of GP, sealer, and voids were measured in the region of 0–2, 2–4, 4–6, and 6–8 mm from the apex, using image analysis of sagittal µCT scans. GP volume percentages were: AH Plus (75.5%), EndoSequence BC (87.3%), and prototype S-PRG (94.4%). Sealer volume percentages were less: AH Plus (14.3%), EndoSequence BC (6.8%), and prototype S-PRG (4.6%). Void percentages were AH Plus (10.1%), EndoSequence BC (5.9%), and prototype S-PRG (1.0%). Dentin-sealer contact ratios of AH Plus, EndoSequence BC, and prototype S-PRG groups were 82.4% ± 6.8%, 71.6% ± 25.3%, and 70.2% ± 9.4%, respectively. GP-sealer contact ratios of AH Plus, EndoSequence BC, and prototype S-PRG groups were 65.6% ± 29.1%, 80.7% ± 25.8%, and 87.0% ± 8.6%, respectively.

Conclusions

Prototype S-PRG sealer created a low-void obturation, similar to EndoSequence BC sealer with similar dentin-sealer contact (> 70%) and GP-sealer contact (> 80%). Prototype S-PRG sealer presented comparable filling quality to EndoSequence BC sealer.

Citations

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Assessment of gap areas of root filling techniques in teeth with 3D-printed different configurations of C-shaped root canals: a micro-computed tomography study
Tuba Gok, Adem Gok, Haydar Onur Aciksoz
BMC Oral Health.2025;[Epub] CrossRef
Assessment of the quality of root canal filling using three different sealers: Micro-computed tomography and scanning electron microscope study
Loai Alsofi, Mohammed Yagmoor, Tariq AbuHaimed, Hassan Abed, Ehab Alshouibi, Rafif Mandura, Turki Bakhsh, Hanaa Ashkar, Mey Al-Habib
Saudi Endodontic Journal.2025; 15(2): 152. CrossRef
Assessment of isthmus filling using two obturation techniques performed by students with different levels of clinical experience
Yang Yu, Chong-Yang Yuan, Xing-Zhe Yin, Xiao-Yan Wang
Journal of Dental Sciences.2024; 19(1): 169. CrossRef
Micro-CT determination of the porosity of two tricalcium silicate sealers applied using three obturation techniques
Jinah Kim, Kali Vo, Gurmukh S. Dhaliwal, Aya Takase, Carolyn Primus, Takashi Komabayashi
Journal of Oral Science.2024; 66(3): 163. CrossRef
Ex-vivo evaluation of clinically-set hydraulic sealers used with different canal dryness protocols and obturation techniques: a randomized clinical trial
Nawar Naguib Nawar, Mohamed Mohamed Elashiry, Ahmed El Banna, Shehabeldin Mohamed Saber, Edgar Schäfer
Clinical Oral Investigations.2024;[Epub] CrossRef
Hydraulic (Single Cone) Versus Thermogenic (Warm Vertical Compaction) Obturation Techniques: A Systematic Review
Haytham S Jaha
Cureus.2024;[Epub] CrossRef
Sealing ability of various endodontic sealers with or without ethylenediaminetetraacetic acid (EDTA) treatment on bovine root canal
Yusuke AIGAMI, Tomofumi SAWADA, Shunsuke SHIMIZU, Akiko ASANO, Mamoru NODA, Shinji TAKEMOTO
Dental Materials Journal.2024; 43(3): 420. CrossRef
A Literature Review of the Effect of Heat on the Physical-Chemical Properties of Calcium Silicate–Based Sealers
Israa Ashkar, José Luis Sanz, Leopoldo Forner, James Ghilotti, María Melo
Journal of Endodontics.2024; 50(8): 1044. CrossRef
Assessment of the Prevalence of Head Lice Infestation and Parents’ Attitudes Towards Its Management: A School-based Epidemiological Study in İstanbul, Türkiye
Özben Özden, İnci Timur, Hale Ezgi Açma, Duygu Şimşekli, Barış Gülerman, Özgür Kurt
Turkish Journal of Parasitology.2023; 47(2): 112. CrossRef
Calcium-doped zinc oxide nanocrystals as an innovative intracanal medicament: a pilot study
Gabriela Leite de Souza, Thamara Eduarda Alves Magalhães, Gabrielle Alves Nunes Freitas, Nelly Xiomara Alvarado Lemus, Gabriella Lopes de Rezende Barbosa, Anielle Christine Almeida Silva, Camilla Christian Gomes Moura
Restorative Dentistry & Endodontics.2022;[Epub] CrossRef
Micro‐CT assessment of gap‐containing areas along the gutta‐percha‐sealer interface in oval‐shaped canals
Gustavo De‐Deus, Gustavo O. Santos, Iara Zamboni Monteiro, Daniele M. Cavalcante, Marco Simões‐Carvalho, Felipe G. Belladonna, Emmanuel J. N. L. Silva, Erick M. Souza, Raphael Licha, Carla Zogheib, Marco A. Versiani
International Endodontic Journal.2022; 55(7): 795. CrossRef
A critical analysis of research methods and experimental models to study root canal fillings
Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
International Endodontic Journal.2022; 55(S2): 384. CrossRef
Use of micro-CT to examine effects of heat on coronal obturation
Ivy Shen, Joan Daniel, Kali Vo, Chul Ahn, Carolyn Primus, Takashi Komabayashi
Journal of Oral Science.2022; 64(3): 224. CrossRef
Obturation of Root Canals By Vertical Condensation of Gutta-Percha – Benefits and Pitfalls
Calkovsky Bruno, Slobodnikova Ladislava, Bacinsky Martin, Janickova Maria
Acta Medica Martiniana.2021; 21(3): 103. CrossRef

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Interface between calcium silicate cement and adhesive systems according to adhesive families and cement maturation: Nelly Pradelle-Plasse, Caroline Mocquot, Katherine Semennikova, Pierre Colon, Brigitte Grosgogeat; Restor Dent Endod 2021;46(1):e3. Published online December 9, 2020; DOI: https://doi.org/10.5395/rde.2021.46.e3

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Objectives

This study aimed to evaluate the interface between a calcium silicate cement (CSC), Biodentine and dental adhesives in terms of sealing ability.

Materials and Methods

Microleakage test: 160 standardized class II cavities were prepared on 80 extracted human molars. The cavities were filled with Biodentine and then divided into 2 experimental groups according to the time of restoration: composite resin obturation 15 minutes after Biodentine handling (D0); restoration after 7 days (D7). Each group was then divided into 8 subgroups (n = 5) according to the adhesive system used: etch-and-rinse adhesive (Prime & Bond); self-etch adhesive 2 steps (Optibond XTR and Clearfil SE Bond); self-etch adhesive 1 step (Xeno III, G-aenial Bond, and Clearfil Tri-S Bond); and universal used as etch-and-rinse or self-etch (ScotchBond Universal ER or SE). After thermocycling, the teeth were immersed in a silver nitrate solution, stained, longitudinally sectioned, and the Biodentine/adhesive percolation was quantified. Scanning electron microscopic observations: Biodentine/adhesive interfaces were observed.

Results

A tendency towards less microleakage was observed when Biodentine was etched (2.47%) and when restorations were done without delay (D0: 4.31%, D7: 6.78%), but this was not significant. The adhesives containing 10-methacryloyloxydecyl dihydrogen phosphate monomer showed the most stable results at both times studied. All Biodentine/adhesive interfaces were homogeneous and regular.

Conclusions

The good sealing of the CSC/adhesive interface is not a function of the system adhesive family used or the cement maturation before restoration. Biodentine can be used as a dentine substitute.

Citations

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Effect of Er Cr YSGG laser etching procedure on the bond strength of different calcium silicate cements
Yesim Sesen Uslu, Hakan Yasin Gönder, Pinar Sesen, Gizem Gunduz Bektaş
Lasers in Dental Science.2024;[Epub] CrossRef
Managing Cracked Teeth with Root Extension: A Prospective Preliminary Study Using Biodentine™ Material
Kênia Maria Soares de Toubes, Isabella Sousa Corrêa, Regina Célia Lopes Valadares, Stephanie Quadros Tonelli, Fábio Fernandes Borém Bruzinga, Frank Ferreira Silveira, Dr Karthikeyan Ramalingam
International Journal of Dentistry.2024;[Epub] CrossRef
In Vitro Resistance of Natural Molars vs. Additive-Manufactured Simulators Treated with Pulpotomy and Endocrown
Marie-Laure Munoz-Sanchez, Alexis Gravier, Olivier Francois, Emmanuel Nicolas, Martine Hennequin, Nicolas Decerle
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Shade reproduction and the ability of lithium disilicate ceramics to mask dark substrates: Maryam Iravani, Sayna Shamszadeh, Narges Panahandeh, Seyedeh Mahsa Sheikh-Al-Eslamian, Hassan Torabzadeh; Restor Dent Endod 2020;45(3):e41. Published online July 16, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e41

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Objectives

This study aimed to evaluate the ability of lithium disilicate ceramics to reproduce the A2 shade and to mask A4 substrates.

Materials and Methods

Twenty-four discs (8 mm in diameter, shade A2) of high translucency (groups 1–3) and low translucency (groups 4–6) of IPS e.max ceramic with different thicknesses (0.5, 0.75, and 1 mm) were fabricated as monolithic structures. In addition, discs of medium opacity (group 7–8) with different core/veneer combinations (0.3 mm/0.7 mm and 0.5 mm/0.5 mm) were fabricated as bilayer structures. Specimens were superimposed on an A4 substrate (complex). The color changes of the complex were measured using a spectrophotometer on a black background, and the ΔE values of the complex were compared with either the A4 substrate or the A2 shade tab. One-way analysis of variance, the Tukey honest significant difference test, and the Fisher test were used to analyze the data (p < 0.05).

Results

Significant between-group differences were found for comparisons to both the A4 substrate and the A2 shade (p < 0.05). When compared with the A4 substrate, the ΔE values in all groups were in the non-acceptable range. When compared with the A2 shade, the ΔE values in all groups, except groups 2 and 3, were in the clinically acceptable range.

Conclusions

All translucencies and thicknesses masked the underlying dark substrate. However, the low-translucency IPS e.max Press better reproduced the A2 shade.

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Review Article

Calcium silicate-based root canal sealers: a literature review: Miyoung Lim, Chanyong Jung, Dong-Hoon Shin, Yong-bum Cho, Minju Song; Restor Dent Endod 2020;45(3):e35. Published online June 9, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e35

Abstract PDF PubReader ePub

Epoxy resin-based sealers are currently widely used, and several studies have considered AH Plus to be the gold-standard sealer. However, it still has limitations, including possible mutagenicity, cytotoxicity, inflammatory response, and hydrophobicity. Drawing upon the advantages of mineral trioxide aggregate, calcium silicate-based sealers were introduced with high levels of biocompatibility and hydrophilicity. Because of the hydrophilic environment in root canals, water resorption and solubility of root canal sealers are important factors contributing to their stability. Sealers displaying lower microleakage and stronger push-out bond strength are also needed to endure the dynamic tooth environment. Although the physical properties of calcium silicate-based sealers meet International Organization for Standardization recommendations, and they have consistently reported to be biocompatible, they have not overcome conventional resin-based sealers in actual practice. Therefore, further studies aiming to improve the physical properties of calcium silicate-based sealers are needed.

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Jessica Emanuella Rocha Paz, Priscila Oliveira Costa, Albert Alexandre Costa Souza, Ingrid Macedo de Oliveira, Lucas Fernandes Falcão, Carlos Alberto Monteiro Falcão, Maria Ângela Area Leão Ferraz, Lucielma Salmito Soares Pinto
Restorative Dentistry & Endodontics.2021;[Epub] CrossRef
Characterization, Antimicrobial Effects, and Cytocompatibility of a Root Canal Sealer Produced by Pozzolan Reaction between Calcium Hydroxide and Silica
Mi-Ah Kim, Vinicius Rosa, Prasanna Neelakantan, Yun-Chan Hwang, Kyung-San Min
Materials.2021; 14(11): 2863. CrossRef
Synthesis and Characterization of Novel Calcium-Silicate Nanobioceramics with Magnesium: Effect of Heat Treatment on Biological, Physical and Chemical Properties
Konstantina Kazeli, Ioannis Tsamesidis, Anna Theocharidou, Lamprini Malletzidou, Jonathan Rhoades, Georgia K. Pouroutzidou, Eleni Likotrafiti, Konstantinos Chrissafis, Theodoros Lialiaris, Lambrini Papadopoulou, Eleana Kontonasaki, Evgenia Lymperaki
Ceramics.2021; 4(4): 628. CrossRef
Calcium Silicate Cements vs. Epoxy Resin Based Cements: Narrative Review
Mario Dioguardi, Cristian Quarta, Diego Sovereto, Giuseppe Troiano, Khrystyna Zhurakivska, Maria Bizzoca, Lorenzo Lo Muzio, Lucio Lo Russo
Oral.2021; 1(1): 23. CrossRef
In Vitro Microleakage Evaluation of Bioceramic and Zinc-Eugenol Sealers with Two Obturation Techniques
Francesco De Angelis, Camillo D’Arcangelo, Matteo Buonvivere, Rachele Argentino, Mirco Vadini
Coatings.2021; 11(6): 727. CrossRef
Efficacy Of Calcium Silicate-Based Sealers In Root Canal Treatment: A Systematic Review
Hattan Mohammed Omar Baismail, Mohammed Ghazi Moiser Albalawi, Alaa Mofareh Thoilek Alanazi, Muhannad Atallah Saleem Alatawi, Badr Soliman Alhussain
Annals of Dental Specialty.2021; 9(1): 87. CrossRef
Apical Sealing Ability of Two Calcium Silicate-Based Sealers Using a Radioactive Isotope Method: An In Vitro Apexification Model
Inês Raquel Pereira, Catarina Carvalho, Siri Paulo, José Pedro Martinho, Ana Sofia Coelho, Anabela Baptista Paula, Carlos Miguel Marto, Eunice Carrilho, Maria Filomena Botelho, Ana Margarida Abrantes, Manuel Marques Ferreira
Materials.2021; 14(21): 6456. CrossRef

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Research Articles

A micro-computed tomographic evaluation of root canal filling with a single gutta-percha cone and calcium silicate sealer: Jong Cheon Kim, Maung Maung Kyaw Moe, Sung Kyo Kim; Restor Dent Endod 2020;45(2):e18. Published online February 12, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e18

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Objectives

The purpose of this study was to evaluate the void of root canal filling over time when a calcium silicate sealer was used in the single gutta-percha cone technique.

Materials and Methods

Twenty-four J-shaped simulated root canals and twenty-four palatal root canals from extracted human maxillary molars were instrumented with ProFile Ni-Ti rotary instruments up to size 35/0.06 or size 40/0.06, respectively. Half of the canals were filled with Endoseal MTA and the other half were with AH Plus Jet using the single gutta-percha cone technique. Immediately after and 4 weeks after the root canal filling, the samples were scanned using micro-computed tomography at a resolution of 12.8 μm. The scanned images were reconstructed using the NRecon software and the void percentages were calculated using the CTan software, and statistically analyzed by 1-way analysis of variance, paired t-test and Tukey post hoc test.

Results

After 4 weeks, there were no significant changes in the void percentages at all levels in both material groups (p > 0.05), except at the apical level of the AH Plus Jet group (p < 0.05) in the simulated root canal showing more void percentage compared to other groups. Immediately after filling the extracted human root canals, the Endoseal MTA group showed significantly less void percentage compared to the AH Plus Jet group (p < 0.05).

Conclusions

Under the limitations of this study, the Endoseal MTA does not seem to reduce the voids over time.

Citations

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Evaluation of various obturation techniques with bioceramic sealers in 3D-printed C-shaped canals
Maryam Gharechahi, Melika Hoseinzadeh, Saeed Moradi, Mina Mehrjouei
BMC Oral Health.2024;[Epub] CrossRef
Comparison of obturation quality in natural and replica teeth root-filled using different sealers and techniques
Chuta Kooanantkul, Richard M Shelton, Josette Camilleri
Clinical Oral Investigations.2023; 27(5): 2407. CrossRef
Obturation canalaire
N. Linas, M.-L. Munoz-Sanchez, N. Decerle, P.-Y. Cousson
EMC - Médecine buccale.2023; 16(5): 1. CrossRef
The Effect of Sealer Application Methods on Voids Volume after Aging of Three Calcium Silicate-Based Sealers: A Micro-Computed Tomography Study
Amre R. Atmeh, Rakan Alharbi, Ibrahim Aljamaan, Abdulrahman Alahmari, Ashwin C. Shetty, Ahmed Jamleh, Imran Farooq
Tomography.2022; 8(2): 778. CrossRef
Clinical Efficacy of Sealer-based Obturation Using Calcium Silicate Sealers: A Randomized Clinical Trial
Ji-hyung Kim, Sin-Yeon Cho, Yoonwoo Choi, Do-hyun Kim, Su-Jung Shin, Il-Young Jung
Journal of Endodontics.2022; 48(2): 144. CrossRef
A critical analysis of research methods and experimental models to study root canal fillings
Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
International Endodontic Journal.2022; 55(S2): 384. CrossRef
Calcium Silicate Cements vs. Epoxy Resin Based Cements: Narrative Review
Mario Dioguardi, Cristian Quarta, Diego Sovereto, Giuseppe Troiano, Khrystyna Zhurakivska, Maria Bizzoca, Lorenzo Lo Muzio, Lucio Lo Russo
Oral.2021; 1(1): 23. CrossRef
Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based Studies
Viresh Chopra, Graham Davis, Aylin Baysan
Materials.2021; 15(1): 229. CrossRef
Micro-computed tomography in preventive and restorative dental research: A review
Mehrsima Ghavami-Lahiji, Reza Tayefeh Davalloo, Gelareh Tajziehchi, Paria Shams
Imaging Science in Dentistry.2021; 51(4): 341. CrossRef
Main and Accessory Canal Filling Quality of a Premixed Calcium Silicate Endodontic Sealer According to Different Obturation Techniques
Su-Yeon Ko, Hae Won Choi, E-Deun Jeong, Vinicius Rosa, Yun-Chan Hwang, Mi-Kyung Yu, Kyung-San Min
Materials.2020; 13(19): 4389. CrossRef

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A micro-computed tomography evaluation of voids using calcium silicate-based materials in teeth with simulated internal root resorption: Vildan Tek, Sevinç Aktemur Türker; Restor Dent Endod 2020;45(1):e5. Published online November 29, 2019; DOI: https://doi.org/10.5395/rde.2020.45.e5

Abstract PDF PubReader ePub

Objectives

The obturation quality of MTA, Biodentine, Total Fill BC root canal sealer (RCS), and warm gutta-percha (WGP) in teeth with simulated internal root resorption (IRR) was evaluated by using micro-computed tomography.

Materials and Methods

Standardized IRR cavities were created using 40 extracted maxillary central incisor teeth and randomly assigned into 4 groups (n = 10). IRR cavities were filled with MTA, Biodentine, Total Fill BC RCS (bulk-fill form) and WGP + Total Fill BC RCS. Percentage of voids between resorptive cavity walls and obturation material (external void), and inside the filling materials (internal voids) were measured.

Results

Total Fill BC sealer in the bulk-fill form presented significantly highest values of external and internal void percentages (p < 0.05). Biodentine showed a significantly lowest external void percentage (p < 0.05). WGP + Total Fill BC RCS presented significantly lower values of internal void percentages than all groups (p < 0.05), except Biodentine (p > 0.05).

Conclusion

None of the filling materials were created void-free obturation in resorption cavities. Biodentine may favor its application in teeth with IRR over Angelus MTA and bulk-fill form of Total Fill BC.

Citations

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Evaluation of Different Techniques and Materials for Filling in 3-dimensional Printed Teeth Replicas with Perforating Internal Resorption by Means of Micro–Computed Tomography
Angelo J.S. Torres-Carrillo, Helena C. Assis, Rodrigo E. Salazar-Gamarra, Leonardo Moreira Teodosio, Alice C. Silva-Sousa, Jardel F. Mazzi-Chaves, Priscila B. Ferreira-Soares, Manoel D. Sousa-Neto, Fabiane C. Lopes-Olhê
Journal of Endodontics.2024; 50(2): 205. CrossRef
Three-Dimensional Measurement of Obturation Quality of Bioceramic Materials in Filling Artificial Internal Root Resorption Cavities Using Different Obturation Techniques: An In Vitro Comparative Study
Ammar M. Sharki, Ahmed H. Ali
Journal of Endodontics.2024; 50(7): 997. CrossRef
Evaluation of calcium hydroxide root canal filling materials by cone beam computed tomography and three-dimensional modeling
Asel Usdat Ozturk, Ekin Dogan, Venus Seyedoskuyi, Berk Senguler, Asli Topaloglu-Ak
Folia Medica.2024; 66(2): 250. CrossRef
Clinical applications of calcium silicate‐based materials: a narrative review
S Küçükkaya Eren
Australian Dental Journal.2023;[Epub] CrossRef
A critical analysis of research methods and experimental models to study root canal fillings
Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
International Endodontic Journal.2022; 55(S2): 384. CrossRef
An Updated Review on Properties and Indications of Calcium Silicate-Based Cements in Endodontic Therapy
Fateme Eskandari, Alireza Razavian, Rozhina Hamidi, Khadije Yousefi, Susan Borzou, Zohaib Khurshid
International Journal of Dentistry.2022; 2022: 1. CrossRef
Efficacy Of Calcium Silicate-Based Sealers In Root Canal Treatment: A Systematic Review
Hattan Mohammed Omar Baismail, Mohammed Ghazi Moiser Albalawi, Alaa Mofareh Thoilek Alanazi, Muhannad Atallah Saleem Alatawi, Badr Soliman Alhussain
Annals of Dental Specialty.2021; 9(1): 87. CrossRef

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Case Report

Surgical management of an accessory canal in a maxillary premolar: a case report: Hee-Jin Kim, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min; Restor Dent Endod 2019;44(3):e30. Published online July 29, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e30

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We report the surgical endodontic treatment of a maxillary first premolar with a lateral lesion that originated from an accessory canal. Although lesions originating from accessory canals frequently heal with simple conventional endodontic therapy, some lesions may need additional and different treatment. In the present case, conventional root canal retreatment led to incomplete healing with the need for further treatment (i.e., surgery). Surgical endodontic management with a fast-setting calcium silicate cement was performed on the accessory canal using a dental operating microscope. At the patient's 9-month recall visit, the lesion was resolved upon radiography.

Citations

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Predictive analysis of root canal morphology in relation to root canal treatment failures: a retrospective study
Mohmed Isaqali Karobari, Vishnu Priya Veeraraghavan, P. J. Nagarathna, Sudhir Rama Varma, Jayaraj Kodangattil Narayanan, Santosh R. Patil
Frontiers in Dental Medicine.2025;[Epub] CrossRef
Endodontic management of internal replacement resorption of two maxillary central incisors with the aid of cone-beam computed tomography as the diagnostic tool: a case report and review of literature
Fatemeh Eskandari, Safoora Sahebi, Negar Ghorbani Jahandizi, Hossein Mofidi
Journal of Medical Case Reports.2025;[Epub] CrossRef
The Impact of the Preferred Reporting Items for Case Reports in Endodontics (PRICE) 2020 Guidelines on the Reporting of Endodontic Case Reports
Sofian Youssef, Phillip Tomson, Amir Reza Akbari, Natalie Archer, Fayjel Shah, Jasmeet Heran, Sunmeet Kandhari, Sandeep Pai, Shivakar Mehrotra, Joanna M Batt
Cureus.2023;[Epub] CrossRef
Main and Accessory Canal Filling Quality of a Premixed Calcium Silicate Endodontic Sealer According to Different Obturation Techniques
Su-Yeon Ko, Hae Won Choi, E-Deun Jeong, Vinicius Rosa, Yun-Chan Hwang, Mi-Kyung Yu, Kyung-San Min
Materials.2020; 13(19): 4389. CrossRef

373 View
5 Download
4 Crossref

Research Articles

Coronal tooth discoloration induced by regenerative endodontic treatment using different scaffolds and intracanal coronal barriers: a 6-month ex vivo study: Noushin Shokouhinejad, Hassan Razmi, Maryam Farbod, Marzieh Alikhasi, Josette Camilleri; Restor Dent Endod 2019;44(3):e25. Published online July 16, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e25

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Objective

The aim of this study was to evaluate discoloration of teeth undergoing regenerative endodontic procedures (REPs) using blood clot or platelet-rich fibrin (PRF) as the scaffolds and different calcium silicate-based materials as the intracanal coronal barriers in an ex vivo model.

Materials and Methods

Forty-eight bovine incisors were prepared and disinfected using 1 mg/mL double antibiotic paste (DAP). The specimens were then randomly divided into 2 groups (n = 24) according to the scaffolds (blood or PRF). After placement of scaffolds each group was divided into 2 subgroups (n = 12) according to the intracanal coronal barriers (ProRoot MTA or Biodentine). The pulp chamber walls were sealed with dentin bonding agent before placement of DAP and before placement of scaffolds. The color changes (∆E) were measured at different steps. The data were analyzed using 2-way analysis of variance.

Results

Coronal discoloration induced by DAP was not clinically perceptible (ΔE ≤ 3.3). Regarding the type of the scaffold, coronal discoloration was significantly higher in blood groups compared with PRF groups at the end of REP and after 1 month (p < 0.05). However, no significant difference was found between PRF and blood clot after 6 months (p > 0.05). Considering the type of intracanal coronal barrier, no significant difference existed between ProRoot MTA and Biodentine (p > 0.05).

Conclusions

With sealing the dentinal tubules of pulp chamber with a dentin bonding agent and application of DAP as an intracanal medicament, coronal color change of the teeth following the use of PRF and blood sealed with either ProRoot MTA or Biodentine was not different at 6-month follow-up.

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Impact of Biodentine Placement on Fracture Resistance and its Influence on Discoloration with Different Scaffolds
Evren Sarıyılmaz, Öznur Sarıyılmaz, Burak Çarıkçıoğlu, Gülşah Uslu, Raif Alan
Journal of Endodontics.2025;[Epub] CrossRef
Effect of pH on the solubility and volumetric change of ready-to-use Bio-C Repair bioceramic material
Luana Raphael da SILVA, Jader Camilo PINTO, Juliane Maria GUERREIRO-TANOMARU, Mário TANOMARU-FILHO
Brazilian Oral Research.2024;[Epub] CrossRef
Efficacy of Potassium Iodide and Glutathione for Correlation of Dentin Discoloration Caused by Silver Diamine Fluoride
Mahsa Samani, Hamid Majzoub, Faramarz Zakavi, Ayyub Mojaddami
Cureus.2024;[Epub] CrossRef
Intracanal medicaments and coronal sealing materials influence on root fracture resistance and coronal discoloration: An in vitro study
Rasoul Sahebalam, Marzie Boskabady, Maryam Naghavi, Samira Dehghanitafti
Saudi Endodontic Journal.2024; 14(2): 199. CrossRef
Potential Crown Discoloration Induced by the Combination of Various Intracanal Medicaments and Scaffolds Applied in Regenerative Endodontic Therapy
NB Altun, A Turkyilmaz
Nigerian Journal of Clinical Practice.2024; 27(7): 897. CrossRef
Evaluation of the effectiveness of different treatment approaches in preventing coronal discoloration caused by regenerative endodontic treatment
Melis Oya Ateş, Zeliha Uğur Aydın
Clinical Oral Investigations.2023; 27(8): 4595. CrossRef
Evaluation of the Effectiveness of Laser-Assisted Bleaching of the Teeth Discolored due to Regenerative Endodontic Treatment
Noushin Shokouhinejad, Mehrfam Khoshkhounejad, Fatemeh Hamidzadeh, Murilo Baena Lopes
International Journal of Dentistry.2022; 2022: 1. CrossRef
Effectiveness of Teeth Whitening after Regenerative Endodontics Procedures: An In Vitro Study
Irini Fagogeni, Joanna Metlerska, Tomasz Falgowski, Maciej Górski, Mariusz Lipski, Alicja Nowicka
Journal of Clinical Medicine.2022; 11(23): 7016. CrossRef
Microstructure and color stability of calcium silicate-based dental materials exposed to blood or platelet-rich fibrin
Noushin Shokouhinejad, Ibrahim Abu Tahun, Shima Saber Tahan, Fatemeh Mohandes, Mohammad H. Nekoofar, Paul M. H. Dummer
Clinical Oral Investigations.2022; 27(3): 1193. CrossRef
Spectrophotometric analysis of internal bleaching of traumatized teeth with coronal discoloration following regenerative endodontic procedures
Jaqueline Lazzari, Walbert Vieira, Vanessa Pecorari, Brenda Paula Figueiredo de Almeida Gomes, José Flávio Affonso de Almeida, Adriana De-Jesus-Soares
Brazilian Journal of Oral Sciences.2021;[Epub] CrossRef
Biological parameters, discolouration and radiopacity of calcium silicate‐based materials in a simulated model of partial pulpotomy
Lilian Vieira Oliveira, Gabriela Leite de Souza, Gisele Rodrigues da Silva, Thamara Eduarda Alves Magalhães, Gabrielle Alves Nunes Freitas, Ana Paula Turrioni, Gabriella Lopes de Rezende Barbosa, Camilla Christian Gomes Moura
International Endodontic Journal.2021; 54(11): 2133. CrossRef
Effect of hydrogel-based antibiotic intracanal medicaments on crown discoloration
Rayan B. Yaghmoor, Jeffrey A. Platt, Kenneth J. Spolnik, Tien Min Gabriel Chu, Ghaeth H. Yassen
Restorative Dentistry & Endodontics.2021;[Epub] CrossRef
The effect of different calcium silicate-based pulp capping materials on tooth discoloration: an in vitro study
Ahmad S. Al-Hiyasat, Dana M. Ahmad, Yousef S. Khader
BMC Oral Health.2021;[Epub] CrossRef
Knowledge, attitudes, and practices of undergraduate students concerning Regenerative Endodontics
Ligia B. da Silva, Mariana Gabriel, Márcia M. Marques, Fernanda C. Carrer, Flávia Gonçalves, Giovanna Sarra, Giovanna L. Carvalho, Ana Armas-Vega, Maria S. Moreira
Minerva Stomatologica.2020;[Epub] CrossRef
Coronal Discoloration Related to Bioceramic and Mineral Trioxide Aggregate Coronal Barrier in Non-vital Mature Teeth Undergoing Regenerative Endodontic Procedures
Mazen Doumani, Mohammad Yaman Seirawan, Kinda Layous, Mohammad Kinan Seirawan
World Journal of Dentistry.2020; 11(1): 52. CrossRef

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Effects of the exposure site on histological pulpal responses after direct capping with 2 calcium-silicate based cements in a rat model: Panruethai Trongkij, Supachai Sutimuntanakul, Puangwan Lapthanasupkul, Chitpol Chaimanakarn, Rebecca Wong, Danuchit Banomyong; Restor Dent Endod 2018;43(4):e36. Published online August 22, 2018; DOI: https://doi.org/10.5395/rde.2018.43.e36

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Objectives

Direct pulp capping is a treatment for mechanically exposed pulp in which a biocompatible capping material is used to preserve pulpal vitality. Biocompatibility tests in animal studies have used a variety of experimental protocols, particularly with regard to the exposure site. In this study, pulp exposure on the occlusal and mesial surfaces of molar teeth was investigated in a rat model.

Materials and Methods

A total of 58 maxillary first molars of Wistar rats were used. Forty molars were mechanically exposed and randomly assigned according to 3 factors: 1) the exposure site (occlusal or mesial), 2) the pulp-capping material (ProRoot White MTA or Bio-MA), and 3) 2 follow-up periods (1 day or 7 days) (n = 5 each). The pulp of 6 intact molars served as negative controls. The pulp of 12 molars was exposed without a capping material (n = 3 per exposure site for each period) and served as positive controls. Inflammatory cell infiltration and reparative dentin formation were histologically evaluated at 1 and 7 days using grading scores.

Results

At 1 day, localized mild inflammation was detected in most teeth in all experimental groups. At 7 days, continuous/discontinuous calcified bridges were formed at exposure sites with no or few inflammatory cells. No significant differences in pulpal response according to the exposure site or calcium-silicate cement were observed.

Conclusions

The location of the exposure site had no effect on rat pulpal healing. However, mesial exposures could be performed easily, with more consistent results. The pulpal responses were not significantly different between the 2 capping materials.

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The road map to proper dental pulp experiments in animal models
Nuha A Elmubarak
International Dental Journal of Student's Research.2024; 11(4): 163. CrossRef
Treatment outcomes of root perforations repaired by calcium silicate-based cements with or without an accelerator: A randomized controlled trial
Kanyarat Tungputsa, Danuchit Banomyong, Sittichoke Osiri, Supachai Sutimuntanakul
Endodontology.2024; 36(4): 315. CrossRef
Biological evaluation of novel phosphorylated pullulan‐based calcium hydroxide formulations as direct pulp capping materials: An in vivo study on a rat model
Md Refat Readul Islam, Rafiqul Islam, Yunqing Liu, Yu Toida, Yasuhiro Yoshida, Hidehiko Sano, Hany Mohamed Aly Ahmed, Atsushi Tomokiyo
International Endodontic Journal.2024; 57(9): 1247. CrossRef
3D-printed microgels supplemented with dentin matrix molecules as a novel biomaterial for direct pulp capping
Diana Cunha, Nayara Souza, Manuela Moreira, Nara Rodrigues, Paulo Silva, Cristiane Franca, Sivaporn Horsophonphong, Ashley Sercia, Ramesh Subbiah, Anthony Tahayeri, Jack Ferracane, Pamela Yelick, Vicente Saboia, Luiz Bertassoni
Clinical Oral Investigations.2022; 27(3): 1215. CrossRef
Calcium silicate and calcium aluminate cements for dentistry reviewed
Carolyn Primus, James L. Gutmann, Franklin R. Tay, Anna B. Fuks
Journal of the American Ceramic Society.2022; 105(3): 1841. CrossRef
Pulpal response to mineral trioxide aggregate containing phosphorylated pullulan-based capping material
Yu TOIDA, Shimpei KAWANO, Rafiqul ISLAM, Fu JIALE, AFM A CHOWDHURY, Shuhei HOSHIKA, Yasushi SHIMADA, Junji TAGAMI, Masahiro YOSHIYAMA, Satoshi INOUE, Ricardo M. CARVALHO, Yasuhiro YOSHIDA, Hidehiko SANO
Dental Materials Journal.2022; 41(1): 126. CrossRef
The Effect of Calcium-Silicate Cements on Reparative Dentinogenesis Following Direct Pulp Capping on Animal Models
Mihai Andrei, Raluca Paula Vacaru, Anca Coricovac, Radu Ilinca, Andreea Cristiana Didilescu, Ioana Demetrescu
Molecules.2021; 26(9): 2725. CrossRef
Histological evaluation of a novel phosphorylated pullulan‐based pulp capping material: An in vivo study on rat molars
Rafiqul Islam, Yu Toida, Fei Chen, Toru Tanaka, Satoshi Inoue, Tetsuya Kitamura, Yasuhiro Yoshida, Abu Faem Mohammad Almas Chowdhury, Hany Mohamed Aly Ahmed, Hidehiko Sano
International Endodontic Journal.2021; 54(10): 1902. CrossRef
Effectiveness of Direct Pulp Capping Bioactive Materials in Dentin Regeneration: A Systematic Review
Ermin Nie, Jiali Yu, Rui Jiang, Xiangzhen Liu, Xiang Li, Rafiqul Islam, Mohammad Khursheed Alam
Materials.2021; 14(22): 6811. CrossRef
A strontium and amorphous calcium phosphate dipped premixed injectable calcium silicate-based ceramic for dental root canal sealing
Huimin Jin, Yuzhu Li, Qingqing Wang, Menglu Dong, Mengmeng Yang, Wendy Chen, Shengrui Wang, Heng Zhang, Shunli Zheng, Chris Ying Cao, Zheng Zhou, Quan-Li Li
Ceramics International.2021; 47(23): 33738. CrossRef
Bioactive tri/dicalcium silicate cements for treatment of pulpal and periapical tissues
Carolyn M. Primus, Franklin R. Tay, Li-na Niu
Acta Biomaterialia.2019; 96: 35. CrossRef

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Bonding of the silane containing multi-mode universal adhesive for lithium disilicate ceramics: Hyun-Young Lee, Geum-Jun Han, Juhea Chang, Ho-Hyun Son; Restor Dent Endod 2017;42(2):95-104. Published online January 25, 2017; DOI: https://doi.org/10.5395/rde.2017.42.2.95

Abstract PDF PubReader ePub

Objectives

This study evaluated the influence of a multi-mode universal adhesive (MUA) containing silane (Single Bond Universal, 3M EPSE) on the bonding of resin cement to lithium disilicate.

Materials and Methods

Thirty IPS e.max CAD specimens (Ivoclar Vivadent) were fabricated. The surfaces were treated as follows: Group A, adhesive that did not contain silane (ANS, Porcelain Bonding Resin, Bisco); Group B, silane (S) and ANS; Group C, hydrofluoric acid (HF), S, and ANS; Group D, MUA; Group E, HF and MUA. Dual-cure resin cement (NX3, Kerr) was applied and composite resin cylinders of 0.8 mm in diameter were placed on it before light polymerization. Bonded specimens were stored in water for 24 hours or underwent a 10,000 thermocycling process prior to microshear bond strength testing. The data were analyzed using multivariate analysis of variance (p < 0.05).

Results

Bond strength varied significantly among the groups (p < 0.05), except for Groups A and D. Group C showed the highest initial bond strength (27.1 ± 6.9 MPa), followed by Group E, Group B, Group D, and Group A. Thermocycling significantly reduced bond strength in Groups B, C, and E (p < 0.05). Bond strength in Group C was the highest regardless of the storage conditions (p < 0.05).

Conclusions

Surface treatment of lithium disilicate using HF and silane increased the bond strength of resin cement. However, after thermocycling, the silane in MUA did not help achieve durable bond strength between lithium disilicate and resin cement, even when HF was applied.

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Jiawen Liu, Suqing Tu, Mingjuan Wang, Du Chen, Chen Chen, Haifeng Xie
BMC Oral Health.2025;[Epub] CrossRef
Influence of different primers and adhesive system combinations on the durability of resin bonding to lithium disilicate
Christine Yazigi, Shila Alawi, Sebastian Wille, Matthias Kern
The Journal of Prosthetic Dentistry.2025;[Epub] CrossRef
Effect of universal adhesives and self-etch ceramic primers on bond strength to glass-ceramics: A systematic review and meta-analysis of in vitro studies
Renally Bezerra Wanderley Lima, Isis de Araújo Ferreira Muniz, Débora e Silva Campos, Fabián Murillo-Gómez, Ana Karina Maciel de Andrade, Rosângela Marques Duarte, Grace Mendonça de Souza
The Journal of Prosthetic Dentistry.2024; 131(3): 392. CrossRef
Effect of the difference water amounts and hydrolysis times of silane coupling agent on the shear bond strength between lithium disilicate glass ceramic and composite resin
Pimchanok OSOTPRASIT, Sasipin LAUVAHUTANON, Yosnarong SIRIMETHAWONG, Patcharanun CHAIAMORNSUP, Pornpot JIANGKONGKHO
Dental Materials Journal.2024; 43(3): 375. CrossRef
Is additional silane application necessary for a new silane‐containing universal adhesive to bond to glass ceramics?
Priscila Luciane da Silva, Hélio Radke Bittencourt, Luiz Henrique Burnett, Ana Maria Spohr
Journal of Esthetic and Restorative Dentistry.2024; 36(10): 1452. CrossRef
The Effect of Various Lasers on the Bond Strength Between Orthodontic Brackets and Dental Ceramics: A Systematic Review and Meta-Analysis
Seyed Ali Mosaddad, Jaafar Abduo, Mehrnaz Zakizade, Hamid Tebyaniyan, Ahmed Hussain
Photobiomodulation, Photomedicine, and Laser Surgery.2024; 42(1): 20. CrossRef
Long-Term Bonding Performance of One-Bottle vs. Two-Bottle Bonding Agents to Lithium Disilicate Ceramics
Masao Irie, Masahiro Okada, Yukinori Maruo, Goro Nishigawa, Takuya Matsumoto
Polymers.2024; 16(16): 2266. CrossRef
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Case Report

Conservative approach of a symptomatic carious immature permanent tooth using a tricalcium silicate cement (Biodentine): a case report: Cyril Villat, Brigitte Grosgogeat, Dominique Seux, Pierre Farge; Restor Dent Endod 2013;38(4):258-262. Published online November 12, 2013; DOI: https://doi.org/10.5395/rde.2013.38.4.258

Abstract PDF PubReader ePub

The restorative management of deep carious lesions and the preservation of pulp vitality of immature teeth present real challenges for dental practitioners. New tricalcium silicate cements are of interest in the treatment of such cases. This case describes the immediate management and the follow-up of an extensive carious lesion on an immature second right mandibular premolar. Following anesthesia and rubber dam isolation, the carious lesion was removed and a partial pulpotomy was performed. After obtaining hemostasis, the exposed pulp was covered with a tricalcium silicate cement (Biodentine, Septodont) and a glass ionomer cement (Fuji IX extra, GC Corp.) restoration was placed over the tricalcium silicate cement. A review appointment was arranged after seven days, where the tooth was asymptomatic with the patient reporting no pain during the intervening period. At both 3 and 6 mon follow up, it was noted that the tooth was vital, with normal responses to thermal tests. Radiographic examination of the tooth indicated dentin-bridge formation in the pulp chamber and the continuous root formation. This case report demonstrates a fast tissue response both at the pulpal and root dentin level. The use of tricalcium silicate cement should be considered as a conservative intervention in the treatment of symptomatic immature teeth.

Citations

Citations to this article as recorded by

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Evaluation of Biodentine Tricalcium Silicate-Based Cement after Chlorhexidine Irrigation
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Evaluation of the chemical, physical, and biological properties of a newly developed bioceramic cement derived from cockle shells: an in vitro study
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Protección pulpar directa y posterior apexogénesis. Informe de un caso clínico / Direct pulp capping followed by apexogenesis. A clinical case report
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Revista de la Asociación Odontológica Argentina.2022;[Epub] CrossRef
The Effect of Irrigation with Citric Acid on Biodentine Tricalcium Silicate-Based Cement: SEM-EDS In Vitro Study
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Research Article

Flexural strength and microstructure of two lithium disilicate glass ceramics for CAD/CAM restoration in the dental clinic: Suk-Ho Kang, Juhea Chang, Ho-Hyun Son; Restor Dent Endod 2013;38(3):134-140. Published online August 23, 2013; DOI: https://doi.org/10.5395/rde.2013.38.3.134

Abstract PDF PubReader ePub

Objectives

There has been a growing interest in glass ceramic systems with good esthetics, high fracture resistance and bonding durability, and simplified fabrication techniques using CAD/CAM. The aim of this study is to compare flexural strength before and after heat treatment of two lithium disilicate CAD/CAM blocks, IPS e.max CAD (Ivoclar Vivadent) and Rosetta SM (Hass), and to observe their crystalline structures.

Materials and Methods

Biaxial flexural strength was tested according to ISO 6872 with 20 disc form specimens sliced from each block before and after heat treatment. Also, the crystalline structures were observed using field-emission scanning microscopy (FE-SEM, Hitachi) and x-ray diffraction (XRD, Rigaku) analysis. The mean values of the biaxial flexural strength were analyzed by the Mann-Whitney U test at a significance level of p = 0.05.

Results

There were no statistically significant differences in flexural strength between IPS e.max CAD and Rosetta SM either before heat treatment or after heat treatment. For both ceramics, the initial flexural strength greatly increased after heat treatment, with significant differences (p < 0.05). The FE-SEM images presented similar patterns of crystalline structure in the two ceramics. In the XRD analysis, they also had similar patterns, presenting high peak positions corresponding to the standard lithium metasilicate and lithium disilicate at each stage of heat treatment.

Conclusions

IPS e.max CAD and Rosetta SM showed no significant differences in flexural strength. They had a similar crystalline pattern and molecular composition.

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Review Article

Chemical characteristics of mineral trioxide aggregate and its hydration reaction: Seok-Woo Chang; Restor Dent Endod 2012;37(4):188-193. Published online November 21, 2012; DOI: https://doi.org/10.5395/rde.2012.37.4.188

Abstract PDF PubReader ePub

Mineral trioxide aggregate (MTA) was developed in early 1990s and has been successfully used for root perforation repair, root end filling, and one-visit apexification. MTA is composed mainly of tricalcium silicate and dicalcium silicate. When MTA is hydrated, calcium silicate hydrate (CSH) and calcium hydroxide is formed. Formed calcium hydroxide interacts with the phosphate ion in body fluid and form amorphous calcium phosphate (ACP) which finally transforms into calcium deficient hydroxyapatite (CDHA). These mineral precipitate were reported to form the MTA-dentin interfacial layer which enhances the sealing ability of MTA. Clinically, the use of zinc oxide euginol (ZOE) based materials may retard the setting of MTA. Also, the use of acids or contact with excessive blood should be avoided before complete set of MTA, because these conditions could adversely affect the hydration reaction of MTA. Further studies on the chemical nature of MTA hydration reaction are needed.

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