This study evaluated the safety of an office bleaching gel (RemeWhite, Remedent Inc., Deurle, Belgium) containing 30% hydrogen peroxide. 37 volunteers were recieved office bleaching with the RemeWhite for 3 times at one visit, total 2 visits. As control group, the same gel in which hydrogen peroxide was not included was applied to 34 volunteers with the same protocol.

There was no difference between experimental group and control group using electric pulp test. In the result of gingival inflammation index and tooth sensitivity test, there was mild pain response in experimental group but it disappeared as time went by. Therefore, safety of the office bleaching gel containing 30% hydrogen peroxide was confirmed.

Citations

Citations to this article as recorded by  

• Clinical assessment of whitening efficacy and safety of in-office tooth whitening system containing 15% hydrogen peroxide with or without light activation
  Young-Suk Noh, Young-Jee Rho, Yeon-Jee Yoo, Hyang-Ok Lee, Sang-Min Lim, Hyun-Jeong Kweon, Yeun Kim, Seong-Yeon Park, Hee-Young Yoon, Jung-Hyun Lee, Chan-Hee Lee, So-Ram Oh, Kee-Yeon Kum
  Journal of Korean Academy of Conservative Dentistry.2011; 36(4): 306.     CrossRef

This clinical study evaluated the whitening effect and safety of polymer based-pen type BlancTis Forte (NIBEC) containing 8.3% carbamide peroxide. Twenty volunteers used the BlancTis Forte whitening agent for 2 hours twice a day for 4 weeks. As a control, Whitening Effect Pen (LG) containing 3% hydrogen peroxide was used by 20 volunteers using the same protocol. The change in shade (ΔE^*, color difference) was measured using Shadepilot™ (DeguDent) before, during, and after bleaching (2 weeks, 4 weeks, and post-bleaching 4 weeks). A clinical examination for any side effects (tooth hypersensitivity or soft tissue complications) was also performed at each check-up. The following results were obtained.

1. Both the experimental and control groups displayed a noticeable change in shade (ΔE) of over 2. No significant differences were found between the two groups (p > 0.05), implying that the two agents have a similar whitening effect.

2. The whitening effect was mainly due to changes in a and b values rather than in L value (brightness). The experimental group showed a significantly higher change in b value, thus yellow shade, than the control (p < 0.05).

3. None of the participants complained of tooth hypersensitivity or soft tissue complications, confirming the safety of both whitening agents.

Citations

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• Surface Damage and Bleaching Effect according to the Application Type of Home Tooth Bleaching Applicants
  Na-Yeoun Tak, Do-Seon Lim, Hee-Jung Lim, Im-Hee Jung
  Journal of Dental Hygiene Science.2020; 20(4): 252.     CrossRef
• Efficacy of a self - applied paint - on whitening gel combined with wrap
  Soo-Yeon Kim, Jae-Hyun Ahn, Ji-Young Kim, Jin-Woo Kim, Se-Hee Park, Kyung-Mo Cho
  Journal of Dental Rehabilitation and Applied Science.2018; 34(3): 175.     CrossRef

This study evaluated the effectiveness and safety of an experimental bleaching strip (Medison dental whitening strip, Samsung medical Co., Anyang, Korea) containing 2.9% hydrogen peroxide. Twenty-three volunteers used the bleaching strips for one and a half hour daily for 2 weeks. As control group, the same strips in which hydrogen peroxide was not included were used by 24 volunteers with the same protocol. The shade change (ΔE*, color difference) of twelve anterior teeth was measured using Shade Vision (X-Rite Inc., S.W. Grandville, MI, USA), Chroma Meter (Minolta Co., Ltd. Osaka, Japan) and Vitapan classical shade guide (Vita Zahnfabrik, Germany). The shade change of overall teeth in the experimental group was significantly greater than that in the control group (p < 0.05) and was easily perceivable. The change resulted from the increase of lightness (CIE L* value) and the decrease of redness (CIE a* value) and yellowness (CIE b* value). The shade change of individual tooth was greatest in canine, and smallest in central incisor. The safety of the bleaching strip was also confirmed.

Citations

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• Effect of at-home agents and concentrations on bleaching efficacy: A systematic review and network meta-analysis
  Renata Maria Oleniki Terra, Michael Willian Favoreto, Tom Morris, Alessandro D. Loguercio, Alessandra Reis
  Journal of Dentistry.2025; 160: 105857.     CrossRef
• Effects of Citrus limon Extract on Oxidative Stress-Induced Nitric Oxide Generation and Bovine Teeth Bleaching
  Soon-Jeong Jeong
  Journal of Dental Hygiene Science.2021; 21(2): 96.     CrossRef
• Efficacy of a self - applied paint - on whitening gel combined with wrap
  Soo-Yeon Kim, Jae-Hyun Ahn, Ji-Young Kim, Jin-Woo Kim, Se-Hee Park, Kyung-Mo Cho
  Journal of Dental Rehabilitation and Applied Science.2018; 34(3): 175.     CrossRef
• Effects of a whitening strip combined with a desensitizing primer on tooth color
  Hae-Eun Shin, Sang-Uk Im, Eun-Kyung Kim, Jong-Hun Kim, Jae-Hyun Ahn, Youn-Hee Choi, Keun-Bae Song
  Journal of Korean Academy of Oral Health.2016; 40(1): 31.     CrossRef
• A clinical evaluation of efficacy of an office bleaching gel containing 30% hydrogen peroxide
  Sin-Young Kim, Je-Uk Park, Chang-Hyen Kim, Sung-Eun Yang
  Journal of Korean Academy of Conservative Dentistry.2010; 35(1): 40.     CrossRef
• The evaluation of clinical efficacy and longevity of home bleaching without combined application of In-office bleaching
  Byunk-Gyu Shin, Sung-Eun Yang
  Journal of Korean Academy of Conservative Dentistry.2010; 35(5): 387.     CrossRef
• Effect of the bleaching light on whitening efficacy
  Jong-Hyun Park, Hye-Jin Shin, Deok-Young Park, Se-Hee Park, Jin-Woo Kim, Kyung-Mo Cho
  Journal of Korean Academy of Conservative Dentistry.2009; 34(2): 95.     CrossRef
• Clinical study of shade improvement and safety of polymer-based pen type BlancTic Forte whitening agent containing 8.3% Carbamide peroxide
  Jin-Kyung Lee, Sun-Hong Min, Sung-Tae Hong, So-Ram Oh, Shin-Hye Chung, Young-Hye Hwang, Sung-Yeop You, Kwang-Shik Bae, Seung-Ho Baek, Woo-Cheol Lee, Won-Jun Son, Kee-Yeon Kum
  Journal of Korean Academy of Conservative Dentistry.2009; 34(2): 154.     CrossRef