Restorative Dentistry & Endodontics

Research Article

Cleaning protocols to enhance bond strength of fiberglass posts on root canals filled with bioceramic sealer: an in vitro comparative study: Thiago Bessa Marconato Antunes, Juliana Delatorre Bronzato, Joice Graciani, Ana Cristina Padilha Janini, Rocharles Cavalcante Fontenele, Francisco Haiter Neto, Brenda Paula Figueiredo de Almeida Gomes, Marina Angélica Marciano da Silva; Restor Dent Endod 2025;50(2):e20. Published online May 21, 2025; DOI: https://doi.org/10.5395/rde.2025.50.e20

Abstract PDF PubReader ePub: Objectives
This study aimed to evaluate whether the agitation protocols using ultrasonic inserts or the XP-endo Finisher R file improved the removal of two different endodontic sealer remnants and the bond strength of fiberglass posts to dentin.
Methods
Seventy-two human teeth were selected. The canals were prepared with Reciproc 50 and Easy ProDesign 30/.10 and root filled according to the endodontic sealer groups: AH Plus or EndoSequence BC Sealer HiFlow. The samples were kept at 37ºC and 95% humidity for 28 days. During the post space preparation, the obturation was removed with Largo burs, and the groups were divided according to the irrigant agitation protocols (n = 12): no agitation, agitation with R1-Clearsonic associated with E1-Irrisonic ultrasonic inserts, or agitation with XP-endo Finisher R file. The fiberglass posts were cemented with RelyX ARC. The roots were sectioned into slices and submitted to the push-out test. Micro-computed tomography analysis was used to check the effectiveness of irrigating solution agitation in the elimination of remnants.
Results
The cleaning protocols with agitation were more effective in increasing the bond strength of posts to dentin for both sealer groups compared to non-agitation (p < 0.05). There was no difference between the same cleaning protocols for the different sealers. Among the different thirds, there was no statistical difference for the same sealer in the different cleaning protocols (p > 0.05).
Conclusions
Both agitation protocols effectively clean root-filled canals sealed with resin-based and calcium silicate-based sealers during fiberglass post space preparation. These protocols result in improved bond strength compared to non-agitation methods.

566 View
70 Download

Review Article

Success rate of direct pulp capping on permanent teeth using bioactive materials: a systematic review and meta-analysis of randomized clinical trials: Karem Paula Pinto, Gabriela Ribeiro da Silva, Cláudio Malizia Alves Ferreira, Luciana Moura Sassone, Emmanuel João Nogueira Leal da Silva; Restor Dent Endod 2024;49(4):e34. Published online September 6, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e34

Abstract PDF Supplementary Material PubReader ePub: This systematic review and meta-analysis aimed to evaluate the success rate of direct pulp capping (DPC) on permanent teeth, comparing the use of MTA with calcium hydroxide and calcium silicate-based cements. A systematic search was carried out in 4 databases until July 2023. The selection was based on PICOS criteria and only randomized clinical trials were included. The risk of bias was assessed using RoB-2 tool, and meta-analyses were performed using RevMan 5.3 software. The overall quality of evidence was determined using the GRADE tool. Thirteen studies were included. Meta-analyses indicated significantly higher success rate for DPC using MTA compared to calcium hydroxide, while no significant difference was observed between MTA and Biodentine, showing a success rate from 80% to 100% even after 3 years of follow-up. Five studies were classified as having high risk of bias and the GRADE assessment revealed low certainty of evidence. DPC is highly effective for permanent teeth when using MTA or Biodentine. There is a need for future well-designed randomized clinical trials to evaluate the efficacy of DPC using newer bioceramic materials.

4,917 View
236 Download

Research Articles

Nanoleakage of apical sealing using a calcium silicate-based sealer according to canal drying methods: Yoon-Joo Lee, Kyung-Mo Cho, Se-Hee Park, Yoon Lee, Jin-Woo Kim; Restor Dent Endod 2024;49(2):e20. Published online April 19, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e20

Abstract PDF PubReader ePub: Objectives
This study investigated the nanoleakage of root canal obturations using calcium silicate-based sealer according to different drying methods.
Materials and Methods
Fifty-two extracted mandibular premolars with a single root canal and straight root were selected for this study. After canal preparation with a nickel-titanium rotary file system, the specimens were randomly divided into 4 groups according to canal drying methods (1: complete drying, 2: blot drying/distilled water, 3: blot drying/NaOCl, 4: aspiration only). The root canals were obturated using a single-cone filling technique with a calcium silicate–based sealer. Nanoleakage was evaluated using a nanoflow device after 24 hours, 1 week, and 1 month. Data were collected twice per second at the nanoscale and measured in nanoliters per second. Data were statistically analyzed using the Kruskal-Wallis and Mann–Whitney U-tests (p < 0.05).
Results
The mean flow rate measured after 24 hours showed the highest value among the time periods in all groups. However, the difference in the flow rate between 1 week and 1 month was not significant. The mean flow rate of the complete drying group was the highest at all time points. After 1 month, the mean flow rate in the blot drying group and the aspiration group was not significantly different.
Conclusions
Within the limitations of this study, the canal drying method had a significant effect on leakage and sealing ability in root canal obturations using a calcium silicate-based sealer. Thus, a proper drying procedure is critical in endodontic treatment.

817 View
59 Download

Pulp stones: any relevance with the levels of serum calcium, parathyroid hormone, vitamin D and uric acid: Ceyda Gürhan, Ercan Saruhan; Restor Dent Endod 2024;49(2):e17. Published online March 26, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e17

Abstract PDF PubReader ePub

Objectives

This study evaluated the effect of serum calcium, parathyroid hormone (PTH), vitamin D, and uric acid levels on pulp stone formation.

Materials and Methods

Patients who were admitted to the Muğla Sıtkı Koçman University, Faculty of Dentistry, Department of Oral and Maxillofacial Radiology for dental complaints were registered. Among these patients, individuals who had routine biochemical tests at the same period in the Outpatient Clinics of Muğla Sıtkı Koçman University Training and Research Hospital were included in the study. The patients with at least 1 pulp stone on panoramic radiographs recorded as the “pulp stone group” while patients without any pulp stones were the “control group”. Demographic data and serum levels of calcium, PTH, vitamin D, and uric acid were retrospectively evaluated in both groups. Student t-test or Mann-Whitney U test was used to evaluate the differences between the groups.

Results

Among 151 patients, dental pulp stone was detected in 53.6% of patients, and 82.7% of these patients were female. Female sex and pulp stone formation were significantly associated (p = 0.001). The mean age of the pulp stone group was 43.9, while it was 39.9 in the control group, without any significant correlation between age and pulp stone (p > 0.05). Similarly, there were no significant differences in serum levels of PTH, vitamin D, uric acid and calcium between groups (p > 0.05).

Conclusions

According to the present study, the effect of dental factors rather than systemic factors should be considered primarily in pulp stone formation.

Citations

Citations to this article as recorded by

A novel deep learning-based pipeline architecture for pulp stone detection on panoramic radiographs
Ceyda Gürhan, Hasan Yiğit, Selim Yılmaz, Cihat Çetinkaya
Oral Radiology.2025; 41(2): 285. CrossRef
Vitamin D deficiency and oral health: a systematic review of literature
Saida Ziada, Aws Wishahe, Najet Mabrouk, Souad Sahtout
BMC Oral Health.2025;[Epub] CrossRef

1,147 View
54 Download
2 Web of Science
2 Crossref

Case Report

Garre’s osteomyelitis of the mandible managed by nonsurgical re-endodontic treatment: Heegyun Kim, Jiyoung Kwon, Hyun-Jung Kim, Soram Oh, Duck-Su Kim, Ji-Hyun Jang; Restor Dent Endod 2024;49(2):e13. Published online March 18, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e13

Abstract PDF PubReader ePub

Chronic osteomyelitis with proliferative periostitis, known as Garre’s osteomyelitis, is a type of osteomyelitis characterized by a distinctive gross thickening of the periosteum of bones. Peripheral reactive bone formation can be caused by mild irritation or infection. Garre’s osteomyelitis is usually diagnosed in children and young adults, and the mandible is more affected than the maxilla. The following is a case report of a 12-year-old female patient with Garre’s osteomyelitis of the mandible due to an infection of a root canal-treated tooth. Without surgical intervention, the patient’s symptoms were relieved through nonsurgical root canal re-treatment with long-term calcium hydroxide placement. A cone-beam computed tomography image obtained 6 months after treatment completion displayed complete healing of the periapical lesion and resolution of the peripheral reactive buccal bone. Due to the clinical features of Garre's osteomyelitis, which is characterized by thickening of the periosteum, it can be mistaken for other diseases such as fibrous dysplasia. It is important to correctly diagnose Garre's osteomyelitis based on its distinctive clinical features to avoid unnecessary surgical intervention, and it can lead to minimally invasive treatment options.

Citations

Citations to this article as recorded by

Focal osteomyelitis with proliferative periostitis
Zarah Yakoob
South African Dental Journal.2025; 79(09): 508. CrossRef

2,693 View
86 Download
1 Web of Science
1 Crossref

Research Articles

A scientometric, bibliometric, and thematic map analysis of hydraulic calcium silicate root canal sealers: Anastasios Katakidis, Konstantinos Kodonas, Anastasia Fardi, Christos Gogos; Restor Dent Endod 2023;48(4):e41. Published online November 13, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e41

Abstract PDF PubReader ePub

Objectives

This scientometric and bibliometric analysis explored scientific publications related to hydraulic calcium silicate-based (HCSB) sealers used in endodontology, aiming to describe basic bibliometric indicators and analyze current research trends.

Materials and Methods

A comprehensive search was conducted in Web of Science and Scopus using specific HCSB sealer and general endodontic-related terms. Basic research parameters were collected, including publication year, authorship, countries, institutions, journals, level of evidence, study design and topic of interest, title terms, author keywords, citation counts, and density.

Results

In total, 498 articles published in 136 journals were retrieved for the period 2008–2023. Brazil was the leading country, and the universities of Bologna in Italy and Sao Paolo in Brazil were represented equally as leading institutions. The most frequently occurring keywords were “calcium silicate,” “root canal sealer MTA-Fillapex,” and “biocompatibility,” while title terms such as “calcium,” “sealers,” “root,” “canal,” “silicate based,” and “endodontic” occurred most often. According to the thematic map analysis, “solubility” appeared as a basic theme of concentrated research interest, and “single-cone technique” was identified as an emerging, inadequately developed theme. The co-occurrence analysis revealed 4 major clusters centered on sealers’ biological and physicochemical properties, obturation techniques, retreatability, and adhesion.

Conclusions

This analysis presents bibliographic features and outlines changing trends in HCSB sealer research. The research output is dominated by basic science articles scrutinizing the biological and specific physicochemical properties of commonly used HCSB sealers. Future research needs to be guided by studies with a high level of evidence that utilize innovative, sophisticated technologies.

Citations

Citations to this article as recorded by

Agri-Food Sector: Contemporary Trends, Possible Gaps, and Prospective Directions
José Roberto Herrera Cantorani, Meire Ramalho de Oliveira, Luiz Alberto Pilatti, Thales Botelho de Sousa
Metrics.2025; 2(1): 3. CrossRef
Scientific mapping of experimental research on solar cookers: Global trends, evolution, and future directions
Flavio Odoi-Yorke, Bismark Baah, Richard Opoku
Solar Energy Advances.2025; 5: 100093. CrossRef
Bibliometric analysis of the GentleWave system: trends, collaborations, and research gaps
Raimundo Sales de Oliveira Neto, Thais de Moraes Souza, João Vitor Oliveira de Amorim, Thaine Oliveira Lima, Guilherme Ferreira da Silva, Rodrigo Ricci Vivan, Murilo Priori Alcalde, Marco Antonio Hungaro Duarte
Restorative Dentistry & Endodontics.2025; 50(2): e17. CrossRef
A bibliometric analysis of global research trend and progress on Dy doped materials
Sangeeta Kadyan, Manju Nain, Ashima Makhija, Poonam Punia, Anil Ohlan, Sajjan Dahiya, R. Punia, A.S. Maan
Journal of Alloys and Compounds Communications.2024; 3: 100006. CrossRef
Comparative bioactivity and immunomodulatory potential of the new Bioroot Flow and AH Plus Bioceramic sealer: An in vitro study on hPDLSCs
José Luis Sanz, Sergio López-García, David García-Bernal, Francisco Javier Rodríguez-Lozano, Leopoldo Forner, Adrián Lozano, Laura Murcia
Clinical Oral Investigations.2024;[Epub] CrossRef
Analyzing collaboration and impact: A bibliometric review of four highly published authors’ research profiles on collaborative maps
Willy Chou, Julie Chi Chow
Medicine.2024; 103(28): e38686. CrossRef

731 View
21 Download
3 Web of Science
6 Crossref

Influence of access cavity design on calcium hydroxide removal using different cleaning protocols: a confocal laser scanning microscopy study: Seda Falakaloğlu, Merve Yeniçeri Özata, Betül Güneş, Emmanuel João Nogueira Leal Silva, Mustafa Gündoğar, Burcu Güçyetmez Topal; Restor Dent Endod 2023;48(3):e25. Published online July 24, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e25

Abstract PDF PubReader ePub

Objectives

The purpose of this study was to evaluate the influence of endodontic access cavities design on the removal of calcium hydroxide medication of the apical third of mandibular incisor root canal walls and dentinal tubules with different cleaning protocols: EDDY sonic activation, Er,Cr:YSGG laser-activated irrigation, or conventional irrigation with IrriFlex.

Materials and Methods

Seventy-eight extracted human mandibular incisors were assigned to 6 experimental groups (n = 13) according to the endodontic access cavity and cleaning protocol for calcium hydroxide removal: traditional access cavity (TradAC)/EDDY; ultraconservative access cavity performed in the incisal edge (UltraAC.Inc)/EDDY; TradAC/Er,Cr:YSGG; UltraAC.Inc/Er,Cr:YSGG; TradAC/IrriFlex; or UltraAC.Inc/IrriFlex. Confocal laser scanning microscopy images were used to measure the non-penetration percentage, maximum residual calcium hydroxide penetration depth, and penetration area at 2 and 4 mm from the apex. Data were statistically analyzed using Shapiro-Wilk and WRS2 package for 2-way comparison of non-normally distributed parameters (depth of penetration, area of penetration, and percentage of non-penetration) according to cavity and cleaning protocol with the significance level set at 5%.

Results

The effect of cavity and cleaning protocol interactions on penetration depth, penetration area and non-penetration percentage was not found statistically significant at 2 and 4 mm levels (p > 0.05).

Conclusions

The present study demonstrated that TradAC or UltraAC.Inc preparations with different cleaning protocols in extracted mandibular incisors did not influence the remaining calcium hydroxide at 2 and 4 mm from the apex.

Citations

Citations to this article as recorded by

Effect of Apical Preparation Size and Preparation Taper on Smear Layer Removal Using Two Different Irrigation Needles: A Scanning Electron Microscopy Study
Rania Lebbos, Naji Kharouf, Deepak Mehta, Jamal Jabr, Cynthia Kamel, Roula El Hachem, Youssef Haikel, Marc Krikor Kaloustian
European Journal of Dentistry.2025; 19(03): 678. CrossRef
Combination of Chitosan Nanoparticles, EDTA, and Irrigation Activation Enhances TGF-β1 Release from Dentin: A Laboratory Study
Sıla Nur Usta, Emre Avcı, Ayşe Nur Oktay, Cangül Keskin
Journal of Endodontics.2025;[Epub] CrossRef

816 View
46 Download
1 Web of Science
2 Crossref

Case Report

Successful nonsurgical treatment of type II dens invaginatus with 5 root canals using a self-adjusting file: a case report: George Táccio de Miranda Candeiro, Antônio Sérgio Teixeira de Menezes, Ana Carolina Saldanha de Oliveira, Flávio Rodrigues Ferreira Alves; Restor Dent Endod 2023;48(2):e17. Published online April 27, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e17

Abstract PDF PubReader ePub: The present report describes the endodontic treatment of an Oehlers type II dens invaginatus in a maxillary lateral incisor with 5 root canals, an extremely rare condition. Apical periodontitis and related symptoms were noted. Cone-beam computed tomography was used to aid the diagnosis, reveal tooth morphology, and assist in canal location. The pulp chamber was carefully accessed, and the root canals were explored under magnification. All root canals were prepared with an R25 Reciproc Blue system and sodium hypochlorite (NaOCl) irrigation. After initial preparation, a self-adjusting file (SAF) with NaOCl and ethylenediaminetetraacetic acid was used to complement the disinfection. Additionally, calcium hydroxide medication was applied. Vertical compaction was used to fill the canals with a calcium silicate-based endodontic sealer and gutta-percha. After 12 months, the patient exhibited healing of the periapical region, absence of symptoms, and normal dental function. In conclusion, this nonsurgical treatment protocol was successful in promoting the cure of apical periodontitis. Both complementary disinfection with an SAF and use of calcium hydroxide medication should be considered when choosing the best treatment approach for dens invaginatus with very complex anatomy.

496 View
32 Download

Research Articles

Calcium-doped zinc oxide nanocrystals as an innovative intracanal medicament: a pilot study: Gabriela Leite de Souza, Thamara Eduarda Alves Magalhães, Gabrielle Alves Nunes Freitas, Nelly Xiomara Alvarado Lemus, Gabriella Lopes de Rezende Barbosa, Anielle Christine Almeida Silva, Camilla Christian Gomes Moura; Restor Dent Endod 2022;47(4):e38. Published online October 4, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e38

Abstract PDF PubReader ePub

Objectives

This study investigated the cytotoxicity, radiopacity, pH, and dentinal tubule penetration of a paste of 1.0% calcium-doped zinc oxide nanocrystals (ZnO:1.0Ca) combined with propylene glycol (PRG) or polyethylene glycol and propylene glycol (PEG-PRG).

Materials and Methods

The pastes were prepared by mixing calcium hydroxide [Ca(OH)₂] or ZnO:1.0Ca with PRG or a PEG-PRG mixture. The pH was evaluated after 24 and 96 hours of storage in deionized water. Digital radiographs were acquired for radiopacity analysis and bubble counting of each material. The materials were labeled with 0.1% fluorescein and applied to root canals, and images of their dentinal tubule penetration were obtained using confocal laser scanning microscopy. RAW264.7 macrophages were placed in different dilutions of culture media previously exposed to the materials for 24 and 96 hours and tested for cell viability using the MTT assay. Analysis of variance and the Tukey test (α = 0.05) were performed.

Results

ZnO:1.0Ca materials showed lower viability at 1:1 and 1:2 dilutions than Ca(OH)₂ materials (p < 0.0001). Ca(OH)₂ had higher pH values than ZnO:1.0Ca at 24 and 96 hours, regardless of the vehicle (p < 0.05). ZnO:1.0Ca pastes showed higher radiopacity than Ca(OH)₂ pastes (p < 0.01). No between-material differences were found in bubble counting (p = 0.0902). The ZnO:1.0Ca pastes had a greater penetration depth than Ca(OH)₂ in the apical third (p < 0.0001).

Conclusions

ZnO:1.0Ca medicaments presented higher penetrability, cell viability, and radiopacity than Ca(OH)₂. Higher values of cell viability and pH were present in Ca(OH)₂ than in ZnO:1.0Ca.

Citations

Citations to this article as recorded by

Nano calcium zincate-assisted synthesis of benzo[ d ]thiazol-2-yl phenylisoxazoles: quantum computational, in silico molecular docking simulations and DNA interaction
A. K. Smitha, V. Srinivasa Murthy, B. Vinay Kumar, M. Sennappan, A. H. Shridhar, Lohit Naik, K. Yogendra, N. Madhusudhana
Nucleosides, Nucleotides & Nucleic Acids.2025; : 1. CrossRef

543 View
13 Download
1 Web of Science
1 Crossref

Effects of calcium silicate cements on neuronal conductivity: Derya Deniz-Sungur, Mehmet Ali Onur, Esin Akbay, Gamze Tan, Fügen Daglı-Comert, Taner Cem Sayın; Restor Dent Endod 2022;47(2):e18. Published online March 7, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e18

Abstract PDF PubReader ePub: Objectives
This study evaluated alterations in neuronal conductivity related to calcium silicate cements (CSCs) by investigating compound action potentials (cAPs) in rat sciatic nerves.
Materials and Methods
Sciatic nerves were placed in a Tyrode bath and cAPs were recorded before, during, and after the application of test materials for 60-minute control, application, and recovery measurements, respectively. Freshly prepared ProRoot MTA, MTA Angelus, Biodentine, Endosequence RRM-Putty, BioAggregate, and RetroMTA were directly applied onto the nerves. Biopac LabPro version 3.7 was used to record and analyze cAPs. The data were statistically analyzed.
Results
None of the CSCs totally blocked cAPs. RetroMTA, Biodentine, and MTA Angelus caused no significant alteration in cAPs (p > 0.05). Significantly lower cAPs were observed in recovery measurements for BioAggregate than in the control condition (p < 0.05). ProRoot MTA significantly but transiently reduced cAPs in the application period compared to the control period (p < 0.05). Endosequence RRM-Putty significantly reduced cAPs.
Conclusions
Various CSCs may alter cAPs to some extent, but none of the CSCs irreversibly blocked them. The usage of fast-setting CSCs during apexification or regeneration of immature teeth seems safer than slow-setting CSCs due to their more favorable neuronal effects.

464 View
12 Download

Comparative analysis of bond strength to root dentin and compression of bioceramic cements used in regenerative endodontic procedures: Maykely Naara Morais Rodrigues, Kely Firmino Bruno, Ana Helena Gonçalves de Alencar, Julyana Dumas Santos Silva, Patrícia Correia de Siqueira, Daniel de Almeida Decurcio, Carlos Estrela; Restor Dent Endod 2021;46(4):e59. Published online November 9, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e59

Abstract PDF PubReader ePub

Objectives

This study compared the Biodentine, MTA Repair HP, and Bio-C Repair bioceramics in terms of bond strength to dentin, failure mode, and compression.

Materials and Methods

Fifty-four slices obtained from the cervical third of 18 single-rooted human mandibular premolars were randomly distributed (n = 18). After insertion of the bioceramic materials, the push-out test was performed. The failure mode was analyzed using stereomicroscopy. Another set of cylindrically-shaped bioceramic samples (n = 10) was prepared for compressive strength testing. The normality of data distribution was analyzed using the Shapiro-Wilk test. The Kruskal-Wallis and Friedman tests were used for the push-out test data, while compressive strength was analyzed with analysis of variance and the Tukey test, considering a significance level of 0.05.

Results

Biodentine presented a higher median bond strength value (14.79 MPa) than MTA Repair HP (8.84 MPa) and Bio-C Repair (3.48 MPa), with a significant difference only between Biodentine and Bio-C Repair. In the Biodentine group, the most frequent failure mode was mixed (61%), while in the MTA Repair HP and Bio-C Repair groups, it was adhesive (94% and 72%, respectively). Biodentine showed greater resistance to compression (29.59 ± 8.47 MPa) than MTA Repair HP (18.68 ± 7.40 MPa) and Bio-C Repair (19.96 ± 3.96 MPa) (p < 0.05).

Conclusions

Biodentine showed greater compressive strength than MTA Repair HP and Bio-C Repair, and greater bond strength than Bio-C Repair. The most frequent failure mode of Biodentine was mixed, while that of MTA Repair HP and Bio-C Repair was adhesive.

Citations

Citations to this article as recorded by

Comparación de la resistencia compresiva entre el Agregado Trióxido Mineral y BiodentineTM en perforaciones de furca de molares inferiores permanentes
Jheymy Gerardo Huatuco-Granda, John Paul Torres-Navarro, Rosa Josefina Roncal-Espinoza
Revista Facultad de Odontología.2024;[Epub] CrossRef
Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis
Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura
Restorative Dentistry & Endodontics.2023;[Epub] CrossRef
Evaluation the Marginal Adaptation for the Bio C Repair and Other Root end Filling Material by Using Scanning Electron Microscope (A Comparative In Vitro Study)
Fatimah HAMADHİ, Zainab M.
Cumhuriyet Dental Journal.2023; 26(3): 261. CrossRef
Dentin Bond Strength of Calcium Silicate-Based Materials: A Systematic Review of In Vitro Studies
Natalia Radulica, José Luis Sanz, Adrián Lozano
Applied Sciences.2023; 14(1): 104. CrossRef
Evaluation Of The Push-out Bond Strength Of The Bio-C Repair And Compare It With The Mineral Trioxide Aggregate And Amalgam When Used As Root-end Filling Material
Fatimah R. Hammadi, Zainab M Abdul-Ameer
Dental Hypotheses.2023; 14(2): 62. CrossRef
Effect of different root canal irrigants on push-out bond strength of two novel root-end filling materials
Nada Omar, Rasha M. Abdelraouf, Tamer M. Hamdy
BMC Oral Health.2023;[Epub] CrossRef
Effect of irrigation systems on the bond strength of calcium-silicate-based cement used as pulp barrier in regenerative endodontic treatment
Cihan Hascizmeci, Burak Buldur
Journal of Adhesion Science and Technology.2023; 37(23): 3393. CrossRef

1,003 View
34 Download
3 Web of Science
7 Crossref

Push-out bond strength and marginal adaptation of apical plugs with bioactive endodontic cements in simulated immature teeth: Maria Aparecida Barbosa de Sá, Eduardo Nunes, Alberto Nogueira da Gama Antunes, Manoel Brito Júnior, Martinho Campolina Rebello Horta, Rodrigo Rodrigues Amaral, Stephen Cohen, Frank Ferreira Silveira; Restor Dent Endod 2021;46(4):e53. Published online October 20, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e53

Abstract PDF PubReader ePub

Objectives

This study evaluates the bond strength and marginal adaptation of mineral trioxide aggregate (MTA) Repair HP and Biodentine used as apical plugs; MTA was used as reference material for comparison.

Materials and Methods

A total of 30 single-rooted teeth with standardized, artificially created open apices were randomly divided into 3 groups (n = 10 per group), according to the material used to form 6-mm-thick apical plugs: group 1 (MTA Repair HP); group 2 (Biodentine); and group 3 (white MTA). Subsequently, the specimens were transversely sectioned to obtain 2 (cervical and apical) 2.5-mm-thick slices per root. Epoxy resin replicas were observed under a scanning electron microscope to measure the gap size at the material/dentin interface (the largest and smaller gaps were recorded for each replica). The bond strength of the investigated materials to dentin was determined using the push-out test. The variable bond strengths and gap sizes were evaluated independently at the apical and cervical root dentin slices. Data were analyzed using descriptive and analytic statistics.

Results

The comparison between the groups regarding the variables' bond strengths and gap sizes showed no statistical difference (p > 0.05) except for a single difference in the smallest gap at the cervical root dentin slice, which was higher in group 3 than in group 1 (p < 0.05).

Conclusions

The bond strength and marginal adaptation to root canal walls of MTA HP and Biodentine cement were comparable to white MTA.

Citations

Citations to this article as recorded by

Evaluation of the root dentin bond strength and intratubular biomineralization of a premixed calcium aluminate-based hydraulic bioceramic endodontic sealer
Yu-Na Lee, Min-Kyeong Kim, Hee-Jin Kim, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min
Journal of Oral Science.2024; 66(2): 96. CrossRef
Managing Cracked Teeth with Root Extension: A Prospective Preliminary Study Using Biodentine™ Material
Kênia Maria Soares de Toubes, Isabella Sousa Corrêa, Regina Célia Lopes Valadares, Stephanie Quadros Tonelli, Fábio Fernandes Borém Bruzinga, Frank Ferreira Silveira, Dr Karthikeyan Ramalingam
International Journal of Dentistry.2024;[Epub] CrossRef
Marginal adaptation of customized gutta percha cone with calcium silicate based sealer versus MTA and biodentine apical plugs in simulated immature permanent teeth (an in vitro study)
Mary M. Mina, Sybel M. Moussa, Mahmoud R. Aboelseoud
BMC Oral Health.2024;[Epub] CrossRef
Comparative Evaluation of Push-Out Bond Strength of Conventional Mineral Trioxide Aggregate, Biodentine, a Modified Mineral Trioxide Aggregate, and Two Novel Antibacterial-Enhanced Mineral Trioxide Aggregates
Arokia Rajkumar Shancy Merlin, Vignesh Ravindran, Ganesh Jeevanandan, Rajalakshmanan Eswaramoorthy, Abirami Arthanari
Cureus.2024;[Epub] CrossRef
Push out bond strength of hydraulic cements used at different thicknesses
C. Ruiz Durán, Dra L. Gancedo-Caravia, V. Vera González, C. González Losada
BMC Oral Health.2023;[Epub] CrossRef
Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis
Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura
Restorative Dentistry & Endodontics.2023;[Epub] CrossRef

708 View
13 Download
7 Web of Science
6 Crossref

Micro-computed tomographic evaluation of single-cone obturation with three sealers: Sahar Zare, Ivy Shen, Qiang Zhu, Chul Ahn, Carolyn Primus, Takashi Komabayashi; Restor Dent Endod 2021;46(2):e25. Published online April 16, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e25

Abstract PDF PubReader ePub

Objectives

This study used micro-computed tomography (µCT) to compare voids and interfaces in single-cone obturation among AH Plus, EndoSequence BC, and prototype surface pre-reacted glass ionomer (S-PRG) sealers and to determine the percentage of sealer contact at the dentin and gutta-percha (GP) interfaces.

Materials and Methods

Fifteen single-rooted human teeth were shaped using ProTaper NEXT size X5 rotary files using 2.5% NaOCl irrigation. Roots were obturated with a single-cone ProTaper NEXT GP point X5 with AH Plus, EndoSequence BC, or prototype S-PRG sealer (n = 5/group).

Results

The volumes of GP, sealer, and voids were measured in the region of 0–2, 2–4, 4–6, and 6–8 mm from the apex, using image analysis of sagittal µCT scans. GP volume percentages were: AH Plus (75.5%), EndoSequence BC (87.3%), and prototype S-PRG (94.4%). Sealer volume percentages were less: AH Plus (14.3%), EndoSequence BC (6.8%), and prototype S-PRG (4.6%). Void percentages were AH Plus (10.1%), EndoSequence BC (5.9%), and prototype S-PRG (1.0%). Dentin-sealer contact ratios of AH Plus, EndoSequence BC, and prototype S-PRG groups were 82.4% ± 6.8%, 71.6% ± 25.3%, and 70.2% ± 9.4%, respectively. GP-sealer contact ratios of AH Plus, EndoSequence BC, and prototype S-PRG groups were 65.6% ± 29.1%, 80.7% ± 25.8%, and 87.0% ± 8.6%, respectively.

Conclusions

Prototype S-PRG sealer created a low-void obturation, similar to EndoSequence BC sealer with similar dentin-sealer contact (> 70%) and GP-sealer contact (> 80%). Prototype S-PRG sealer presented comparable filling quality to EndoSequence BC sealer.

Citations

Citations to this article as recorded by

Assessment of gap areas of root filling techniques in teeth with 3D-printed different configurations of C-shaped root canals: a micro-computed tomography study
Tuba Gok, Adem Gok, Haydar Onur Aciksoz
BMC Oral Health.2025;[Epub] CrossRef
Assessment of the quality of root canal filling using three different sealers: Micro-computed tomography and scanning electron microscope study
Loai Alsofi, Mohammed Yagmoor, Tariq AbuHaimed, Hassan Abed, Ehab Alshouibi, Rafif Mandura, Turki Bakhsh, Hanaa Ashkar, Mey Al-Habib
Saudi Endodontic Journal.2025; 15(2): 152. CrossRef
Assessment of isthmus filling using two obturation techniques performed by students with different levels of clinical experience
Yang Yu, Chong-Yang Yuan, Xing-Zhe Yin, Xiao-Yan Wang
Journal of Dental Sciences.2024; 19(1): 169. CrossRef
Micro-CT determination of the porosity of two tricalcium silicate sealers applied using three obturation techniques
Jinah Kim, Kali Vo, Gurmukh S. Dhaliwal, Aya Takase, Carolyn Primus, Takashi Komabayashi
Journal of Oral Science.2024; 66(3): 163. CrossRef
Ex-vivo evaluation of clinically-set hydraulic sealers used with different canal dryness protocols and obturation techniques: a randomized clinical trial
Nawar Naguib Nawar, Mohamed Mohamed Elashiry, Ahmed El Banna, Shehabeldin Mohamed Saber, Edgar Schäfer
Clinical Oral Investigations.2024;[Epub] CrossRef
Hydraulic (Single Cone) Versus Thermogenic (Warm Vertical Compaction) Obturation Techniques: A Systematic Review
Haytham S Jaha
Cureus.2024;[Epub] CrossRef
Sealing ability of various endodontic sealers with or without ethylenediaminetetraacetic acid (EDTA) treatment on bovine root canal
Yusuke AIGAMI, Tomofumi SAWADA, Shunsuke SHIMIZU, Akiko ASANO, Mamoru NODA, Shinji TAKEMOTO
Dental Materials Journal.2024; 43(3): 420. CrossRef
A Literature Review of the Effect of Heat on the Physical-Chemical Properties of Calcium Silicate–Based Sealers
Israa Ashkar, José Luis Sanz, Leopoldo Forner, James Ghilotti, María Melo
Journal of Endodontics.2024; 50(8): 1044. CrossRef
Assessment of the Prevalence of Head Lice Infestation and Parents’ Attitudes Towards Its Management: A School-based Epidemiological Study in İstanbul, Türkiye
Özben Özden, İnci Timur, Hale Ezgi Açma, Duygu Şimşekli, Barış Gülerman, Özgür Kurt
Turkish Journal of Parasitology.2023; 47(2): 112. CrossRef
Calcium-doped zinc oxide nanocrystals as an innovative intracanal medicament: a pilot study
Gabriela Leite de Souza, Thamara Eduarda Alves Magalhães, Gabrielle Alves Nunes Freitas, Nelly Xiomara Alvarado Lemus, Gabriella Lopes de Rezende Barbosa, Anielle Christine Almeida Silva, Camilla Christian Gomes Moura
Restorative Dentistry & Endodontics.2022;[Epub] CrossRef
Micro‐CT assessment of gap‐containing areas along the gutta‐percha‐sealer interface in oval‐shaped canals
Gustavo De‐Deus, Gustavo O. Santos, Iara Zamboni Monteiro, Daniele M. Cavalcante, Marco Simões‐Carvalho, Felipe G. Belladonna, Emmanuel J. N. L. Silva, Erick M. Souza, Raphael Licha, Carla Zogheib, Marco A. Versiani
International Endodontic Journal.2022; 55(7): 795. CrossRef
A critical analysis of research methods and experimental models to study root canal fillings
Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
International Endodontic Journal.2022; 55(S2): 384. CrossRef
Use of micro-CT to examine effects of heat on coronal obturation
Ivy Shen, Joan Daniel, Kali Vo, Chul Ahn, Carolyn Primus, Takashi Komabayashi
Journal of Oral Science.2022; 64(3): 224. CrossRef
Obturation of Root Canals By Vertical Condensation of Gutta-Percha – Benefits and Pitfalls
Calkovsky Bruno, Slobodnikova Ladislava, Bacinsky Martin, Janickova Maria
Acta Medica Martiniana.2021; 21(3): 103. CrossRef

488 View
16 Download
11 Web of Science
14 Crossref

Interface between calcium silicate cement and adhesive systems according to adhesive families and cement maturation: Nelly Pradelle-Plasse, Caroline Mocquot, Katherine Semennikova, Pierre Colon, Brigitte Grosgogeat; Restor Dent Endod 2021;46(1):e3. Published online December 9, 2020; DOI: https://doi.org/10.5395/rde.2021.46.e3

Abstract PDF PubReader ePub

Objectives

This study aimed to evaluate the interface between a calcium silicate cement (CSC), Biodentine and dental adhesives in terms of sealing ability.

Materials and Methods

Microleakage test: 160 standardized class II cavities were prepared on 80 extracted human molars. The cavities were filled with Biodentine and then divided into 2 experimental groups according to the time of restoration: composite resin obturation 15 minutes after Biodentine handling (D0); restoration after 7 days (D7). Each group was then divided into 8 subgroups (n = 5) according to the adhesive system used: etch-and-rinse adhesive (Prime & Bond); self-etch adhesive 2 steps (Optibond XTR and Clearfil SE Bond); self-etch adhesive 1 step (Xeno III, G-aenial Bond, and Clearfil Tri-S Bond); and universal used as etch-and-rinse or self-etch (ScotchBond Universal ER or SE). After thermocycling, the teeth were immersed in a silver nitrate solution, stained, longitudinally sectioned, and the Biodentine/adhesive percolation was quantified. Scanning electron microscopic observations: Biodentine/adhesive interfaces were observed.

Results

A tendency towards less microleakage was observed when Biodentine was etched (2.47%) and when restorations were done without delay (D0: 4.31%, D7: 6.78%), but this was not significant. The adhesives containing 10-methacryloyloxydecyl dihydrogen phosphate monomer showed the most stable results at both times studied. All Biodentine/adhesive interfaces were homogeneous and regular.

Conclusions

The good sealing of the CSC/adhesive interface is not a function of the system adhesive family used or the cement maturation before restoration. Biodentine can be used as a dentine substitute.

Citations

Citations to this article as recorded by

Effect of Er Cr YSGG laser etching procedure on the bond strength of different calcium silicate cements
Yesim Sesen Uslu, Hakan Yasin Gönder, Pinar Sesen, Gizem Gunduz Bektaş
Lasers in Dental Science.2024;[Epub] CrossRef
Managing Cracked Teeth with Root Extension: A Prospective Preliminary Study Using Biodentine™ Material
Kênia Maria Soares de Toubes, Isabella Sousa Corrêa, Regina Célia Lopes Valadares, Stephanie Quadros Tonelli, Fábio Fernandes Borém Bruzinga, Frank Ferreira Silveira, Dr Karthikeyan Ramalingam
International Journal of Dentistry.2024;[Epub] CrossRef
In Vitro Resistance of Natural Molars vs. Additive-Manufactured Simulators Treated with Pulpotomy and Endocrown
Marie-Laure Munoz-Sanchez, Alexis Gravier, Olivier Francois, Emmanuel Nicolas, Martine Hennequin, Nicolas Decerle
Journal of Functional Biomaterials.2023; 14(9): 444. CrossRef
Characterisation of the calcium silicate‐based cement–composite interface and the bonding strength with total‐etch or single/two‐stage self‐etch adhesive systems
Abidin Talha Mutluay, Merve Mutluay
Australian Endodontic Journal.2022; 48(3): 501. CrossRef
Bond Strength of Adhesive Systems to Calcium Silicate-Based Materials: A Systematic Review and Meta-Analysis of In Vitro Studies
Louis Hardan, Davide Mancino, Rim Bourgi, Alejandra Alvarado-Orozco, Laura Emma Rodríguez-Vilchis, Abigailt Flores-Ledesma, Carlos Enrique Cuevas-Suárez, Monika Lukomska-Szymanska, Ammar Eid, Maya-Line Danhache, Maryline Minoux, Youssef Haïkel, Naji Kharo
Gels.2022; 8(5): 311. CrossRef

764 View
24 Download
5 Web of Science
5 Crossref

Review Article

Calcium silicate-based root canal sealers: a literature review: Miyoung Lim, Chanyong Jung, Dong-Hoon Shin, Yong-bum Cho, Minju Song; Restor Dent Endod 2020;45(3):e35. Published online June 9, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e35

Abstract PDF PubReader ePub

Epoxy resin-based sealers are currently widely used, and several studies have considered AH Plus to be the gold-standard sealer. However, it still has limitations, including possible mutagenicity, cytotoxicity, inflammatory response, and hydrophobicity. Drawing upon the advantages of mineral trioxide aggregate, calcium silicate-based sealers were introduced with high levels of biocompatibility and hydrophilicity. Because of the hydrophilic environment in root canals, water resorption and solubility of root canal sealers are important factors contributing to their stability. Sealers displaying lower microleakage and stronger push-out bond strength are also needed to endure the dynamic tooth environment. Although the physical properties of calcium silicate-based sealers meet International Organization for Standardization recommendations, and they have consistently reported to be biocompatible, they have not overcome conventional resin-based sealers in actual practice. Therefore, further studies aiming to improve the physical properties of calcium silicate-based sealers are needed.

Citations

Citations to this article as recorded by

Effect of Different Tapered Gutta-Percha Points on Push-Out Bond Strength of Two Root Canal Sealers
Warattama Suksaphar, Pakit Tungsawat, Ninnita Wongwatanasanti, Siripat Lertnantapanya, Prattana Yodmanothum
European Journal of General Dentistry.2025;[Epub] CrossRef
Effect of Electrical Heat Carrier Temperature on Bacterial Leakage of Endodontically Treated Teeth Using a Bioceramic Sealer
Mir Ahmad Nabavi, Mahmood Reza Kalantar Motamedi, Pedram Fattahi, Saber Khazaei
Clinical and Experimental Dental Research.2025;[Epub] CrossRef
Nanoparticles modified bioceramic sealers on solubility, antimicrobial efficacy, pushout bond strength and marginal adaptation at apical-third of canal dentin
Basil Almutairi, Fahad Alkhudhairy
PeerJ.2025; 13: e18840. CrossRef
Assessing the antimicrobial properties of bioceramic sealers enhanced with herbal extracts against E. faecalis
KS Sachin, K Shibani Shetty, KB Jeyalakshmi, S Harishma, S Harshini
Folia Medica.2025;[Epub] CrossRef
Estudio comparativo de la solubilidad de dos selladores endodónticos biocerámicos y un sellador a base de resinas //Comparative study of the solubility of two bioceramic endodontic sealers and one epoxi-resin based sealer
Alejandro Leonhardt, Nicolás Paduli, Osvaldo Zmener, Miguel Chantiri
Revista de la Asociación Odontológica Argentina.2025; : 1. CrossRef
Enhancing root canal sealing: Exploring the sealing potential of epoxy and calcium silicate-based sealers with chitosan nanoparticle enhancement
S. Harishma, Srilekha Jayakumar, K Shibani Shetty, Barkavi Panchatcharam, Jwaalaa Rajkumar, S. Harshini
Endodontology.2025;[Epub] CrossRef
Evaluation of the Genotoxicity and Cytotoxicity of Bioceramic Endodontic Sealers in HepG2 and V79 Cell Lines: An In Vitro Study Using the Comet and Micronucleus Assays
Antonija Tadin, Marija Badrov, Danijela Juric Kacunic, Nada Galic, Matea Macan, Ivan Kovacic, Davor Zeljezic
Journal of Functional Biomaterials.2025; 16(5): 169. CrossRef
In Vitro Apatite-Forming Ability of Different Root Canal Sealers (A Comparative Study)
Raghad A Al-Askary, Wiaam M. O. Al-Ashou, Sawsan H. Al-Jubori
Journal of International Society of Preventive and Community Dentistry.2025; 15(2): 173. CrossRef
Microstructural and elemental characterization of novel bioactive glass bioceramic sealer using Fourier transform infrared and X-ray diffraction analysis
Poulomi Guha, Pradeep Solete, Delphine Antony, Nishitha Arun, Mohmed Isaqali Karobari, Surendar Ramamoorthi
Journal of Conservative Dentistry and Endodontics.2025; 28(5): 412. CrossRef
Microstructural and Elemental Characterization of Calcium Silicate-Based Sealers
Mateusz Radwanski, Ireneusz Piwonski, Tomasz Szmechtyk, Salvatore Sauro, Monika Lukomska-Szymanska
Nanomaterials.2025; 15(10): 756. CrossRef
Apical negative pressure-enhanced sealer infiltration for obturating long oval-shaped root canals with the single-cone technique
Yaxu Feng, Brian E. Bergeron, Shijin Zhang, Danyang Sun, Kole Fisher, Franklin R. Tay, Bing Fan
Journal of Dentistry.2025; 160: 105909. CrossRef
Effects of different apical preparation sizes and root canal sealers on the fracture resistance of roots aged for 12 months in endodontically retreated mandibular premolars
Dilek Hancerliogullari, Sevda Durust Baris, Ali Turkyilmaz, Ali Erdemir
British Dental Journal.2025;[Epub] CrossRef
Influence of different endodontic treatment protocols on tooth survival: A retrospective cohort study with multistate analysis and group balancing
Ahmed Elmaasarawi, Mohamed Mekhemar, Andreas Bartols
International Endodontic Journal.2025;[Epub] CrossRef
Evaluation of 2,6-xylidine precipitate on sealer penetration of calcium silicate-based sealer and resin-based sealer: An in vitro study
M. B. Kalpana, Divya Shetty, Rajaram Naik
Endodontology.2025; 37(2): 183. CrossRef
Management of rarely seen internal tunnelling root resorption associated with a maxillary permanent incisor
Kirsty A. Carney, Thibault N. E. Colloc, Julie K. Kilgariff
British Dental Journal.2024; 236(12): 955. CrossRef
Top tips for treatment planning: tooth-by-tooth prognosis - Part 3: endodontic prognosis
Prashanti Eachempati, Andrew Harris, Guy Lambourn, Tony Francis, Ewen McColl
British Dental Journal.2024; 237(9): 686. CrossRef
Retreatability of calcium silicate-based sealers based on micro-computed tomographic evaluation − A systematic review
Sundus Mohammed Bukhary
The Saudi Dental Journal.2024; 36(10): 1278. CrossRef
Evaluation of Setting Time, Flowability, Film Thickness, and Radiopacity of Experimental Monocalcium Silicate‐Based Root Canal Sealers
Sukanya Juntha, Pakit Tungsawat, Ninnita Wongwatanasanti, Warattama Suksaphar, Siripat Lertnantapanya, Carlos M. Ardila
International Journal of Dentistry.2024;[Epub] CrossRef
Root Canal Treatment and Demand for Continuing Education among Thai Dental Practitioners
Ninnita Wongwatanasanti, Pakit Tungsawat, Warattama Suksaphar, Siripat Lertnantapanya, Prattana Yodmanotham
The Open Dentistry Journal.2024;[Epub] CrossRef
Clinical outcome of non-surgical root canal treatment using different sealers and techniques of obturation in 237 patients: A retrospective study
Mateusz Radwanski, Krystyna Pietrzycka, Tan Fırat Eyüboğlu, Mutlu Özcan, Monika Lukomska-Szymanska
Clinical Oral Investigations.2024;[Epub] CrossRef
Endodontic sealers after exposure to chlorhexidine digluconate: An assessment of physicochemical properties
Vasileios Kapralos, Josette Camilleri, Andreas Koutroulis, Håkon Valen, Dag Ørstavik, Pia Titterud Sunde
Dental Materials.2024; 40(3): 420. CrossRef
Assessment the bioactivity of zinc oxid eugenol sealer after the addition of different concentrations of nano hydroxyapatite-tyrosine amino acid
Rasha M. Al-Shamaa, Raghad A. Al-Askary
Brazilian Journal of Oral Sciences.2024; 23: e243733. CrossRef
Interfacial adaptation of newly prepared nano-tricalcium silicate-58s bioactive glass-based endodontic sealer
Nawal A. Al-Sabawi, Sawsan Hameed Al-Jubori
Journal of Dental Research, Dental Clinics, Dental Prospects.2024; 18(2): 115. CrossRef
Marginal adaptation of customized gutta percha cone with calcium silicate based sealer versus MTA and biodentine apical plugs in simulated immature permanent teeth (an in vitro study)
Mary M. Mina, Sybel M. Moussa, Mahmoud R. Aboelseoud
BMC Oral Health.2024;[Epub] CrossRef
Solubility of Endoseal and AH26 Root Canal Sealers
Nooshin Fakhari, Ali Reza Mirjani, Abbas Bagheri, Jalil Modaresi
Journal of Research in Dental and Maxillofacial Sciences.2024; 9(1): 1. CrossRef
Novel bioactive nanospheres show effective antibacterial effect against multiple endodontic pathogens
Jin Liu, Haoze Wu, Jun Qiu, Sirui Yang, Doudou Xiang, Xinhua Zhang, Jinxin Kuang, Min Xiao, Qing Yu, Xiaogang Cheng
Heliyon.2024; 10(7): e28266. CrossRef
Evaluation of canal patency and cleanliness following retreatment of bioceramic sealer‐obturated root canals using three different irrigant activation protocols
Daiasharailang Lyngdoh, Sharique Alam, Huma Iftekhar, Surendra Kumar Mishra
Australian Endodontic Journal.2024; 50(3): 475. CrossRef
Antibiofilm Efficacy of Calcium Silicate-Based Endodontic Sealers
Matilde Ruiz-Linares, Vsevolod Fedoseev, Carmen Solana, Cecilia Muñoz-Sandoval, Carmen María Ferrer-Luque
Materials.2024; 17(16): 3937. CrossRef
Enhancing the Biological Properties of Organic–Inorganic Hybrid Calcium Silicate Cements: An In Vitro Study
Minji Choi, Jiyoung Kwon, Ji-Hyun Jang, Duck-Su Kim, Hyun-Jung Kim
Journal of Functional Biomaterials.2024; 15(11): 337. CrossRef
Cytotoxicity and cell migration evaluation of a strontium silicate-based root canal sealer on stem cells from rat apical papilla: an in vitro study
Guanglei Zhou, Yu Zhao, Liangjing Cai, Liwei Liu, Xu Li, Lu Sun, Jiayin Deng
BMC Oral Health.2024;[Epub] CrossRef
An In Vitro Comparative Analysis of Physico–Mechanical Properties of Commercial and Experimental Bioactive Endodontic Sealers
Abdulmajeed Kashaf, Faisal Alonaizan, Khalid S. Almulhim, Dana Almohazey, Deemah Abdullah Alotaibi, Sultan Akhtar, Ashwin C. Shetty, Abdul Samad Khan
Bioengineering.2024; 11(11): 1079. CrossRef
Chemical, Antibacterial, and Cytotoxic Properties of Four Different Endodontic Sealer Leachates Over Time
Jo-Hsun Chen, Veksina Raman, Sarah A. Kuehne, Josette Camilleri, Josefine Hirschfeld
Journal of Endodontics.2024; 50(11): 1612. CrossRef
Comparative Analysis of Fracture Resistance of Endodontic Sealer Types and Filling Methods
Yun Song, Kee-Deog Kim, Bock-Young Jung, Wonse Park, Nan-Sim Pang
Materials.2024; 18(1): 40. CrossRef
Comparative Evaluation of Removal of Bioceramic Sealers Using Rotary Retreatment Files Supplemented with Passive Ultrasonic Activation: An In Vitro Study
Anuradha B Patil, Amrut Bambawale, Pooja R Barghare, Sumanthini V Margasahayam, Divya Naik, Jayeeta S Verma
World Journal of Dentistry.2024; 15(4): 292. CrossRef
Nonsurgical Endodontic Management of Nonperforating Internal Root Resorption in a Maxillary Central Incisor: A Case Report with a 4-Year Follow-Up
Paras M. Gehlot, Divya S. Rajkumar, Annapoorna B. Mariswamy, Upendra Natha N. Reddy, Chaitanya Chappidi
Journal of Pharmacy and Bioallied Sciences.2024; 16(Suppl 3): S3005. CrossRef
Evaluating the Sealing Performance of Endodontic Sealers: Insights Into Achieving Complete Sealing
Ajay Chhabra, Ramya K P., Saravana Prathap, Priyanka Yadav, Himani Mehra, Sona J Parvathy
Cureus.2024;[Epub] CrossRef
Effects of vehicles on the physical properties and biocompatibility of premixed calcium silicate cements
Gitae SON, Gyeung Mi SEON, Sang Hoon CHOI, Hyeong-Cheol YANG
Dental Materials Journal.2024; 43(2): 276. CrossRef
Comparative cytotoxicity study of putty- and powder-type calcium silicate cements
Sora Park, Dohyun Cho, Ji Hyeon Yoon, Yeonjoo Kang, Quang Canh Vo, Gitae Son, Hongjoo Park, Hyeong-Cheol Yang
Korean Journal of Dental Materials.2024; 51(4): 259. CrossRef
Physical-chemical properties and acellular bioactivity of newly prepared nano-tricalcium silicate-58s bioactive glass-based endodontic sealer
Nawal A. Al-Sabawi, Sawsan Hameed Al-Jubori
Journal of Oral Biosciences.2023; 65(4): 305. CrossRef
Dentinal Tubule Penetrability and Bond Strength of Two Novel Calcium Silicate-Based Root Canal Sealers
Karissa Shieh, Jack Yang, Elsa Heng Zhu, Ove Andreas Peters, Sepanta Hosseinpour
Materials.2023; 16(9): 3309. CrossRef
Cytotoxicity and Mineralization Activity of Calcium Silicate-Based Root Canal Sealers Compared to Conventional Resin-Based Sealer in Human Gingival Fibroblast Cells
Mohammad Shokrzadeh, Farzaneh Sadat Motafeghi, Anahita Lotfizadeh, Mohammad Ghorbani, Azam Haddadi Kohsar, Cesar Rogério Pucci
International Journal of Dentistry.2023; 2023: 1. CrossRef
Effect of three different photosensitizers in photodynamic therapy on bond strength of a calcium silicate‐based sealer to radicular dentin
Cihan Küden, Seda Nur Karakaş
Australian Endodontic Journal.2023; 49(S1): 265. CrossRef
Effect of endodontic sealer on postoperative pain: a network meta-analysis
Cynthia Maria Chaves Monteiro, Ana Cristina Rodrigues Martins, Alessandra Reis, Juliana Larocca de Geus
Restorative Dentistry & Endodontics.2023;[Epub] CrossRef
Antimicrobial Activity of Five Calcium Silicate Based Root Canal Sealers against a Multispecies Engineered Biofilm: An In Vitro Study
Carla Zogheib, Issam Khalil, Wajih Hage, Dolla Karam Sarkis, Mireille Kallasy, Germain Sfeir, May Mallah, Roula El Hachem
The Journal of Contemporary Dental Practice.2023; 24(9): 707. CrossRef
Calcium silicate sealers in endodontics
Archana Chavan, Nidambur Ballal
Acta stomatologica Naissi.2023; 39(87): 2624. CrossRef
Assessing the Sealing Performance and Clinical Outcomes of Endodontic Treatment in Patients with Chronic Apical Periodontitis Using Epoxy Resin and Calcium Salicylate Seals
Razvan Mihai Horhat, Bogdan Andrei Bumbu, Laura Orel, Oana Velea-Barta, Laura Cirligeriu, Gratiana Nicoleta Chicin, Marius Pricop, Mircea Rivis, Stefania Dinu, Delia Ioana Horhat, Felix Bratosin, Roxana Manuela Fericean, Rodica Anamaria Negrean, Luminita
Medicina.2023; 59(6): 1137. CrossRef
In Vitro Cytotoxicity and Mineralization Potential of an Endodontic Bioceramic Material
Soumya Sheela, Mohannad Nassar, Fatma M. AlGhalban, Mehmet O. Gorduysus
European Journal of Dentistry.2023; 17(02): 548. CrossRef
Dislodgment Resistance, Adhesive Pattern, and Dentinal Tubule Penetration of a Novel Experimental Algin Biopolymer-Incorporated Bioceramic-Based Root Canal Sealer
Galvin Sim Siang Lin, Norhayati Luddin, Huwaina Abd Ghani, Josephine Chang Hui Lai, Tahir Yusuf Noorani
Polymers.2023; 15(5): 1317. CrossRef
Impact of Final Irrigation Protocol on the Push-Out Bond Strength of Two Types of Endodontic Sealers
Germain Sfeir, Frédéric Bukiet, Wajih Hage, Roula El Hachem, Carla Zogheib
Materials.2023; 16(5): 1761. CrossRef
Clinical Approaches to the Three-Dimensional Endodontic Obturation Protocol for Teeth with Periapical Bone Lesions
Angela Gusiyska, Elena Dyulgerova
Applied Sciences.2023; 13(17): 9755. CrossRef
Evaluating the bioactivity of endodontic sealers with respect to their thermo-nanomechanical properties
Andreea Marica, Luminita Fritea, Florin Banica, Iosif Hulka, Gerlinde Rusu, Cosmin Sinescu, Traian Octavian Costea, Simona Cavalu
Materials Science-Poland.2023; 41(3): 126. CrossRef
Advances and challenges in regenerative dentistry: A systematic review of calcium phosphate and silicate-based materials on human dental pulp stem cells
B. Christie, N. Musri, N. Djustiana, V. Takarini, N. Tuygunov, M.N. Zakaria, A. Cahyanto
Materials Today Bio.2023; 23: 100815. CrossRef
Radiographic Evaluation of Periapical Healing Rates Between Bio-Ceramic Sealer and AH+ Sealer: A Retrospective Study
Dalia Nayil Alharith, Iman T. Mansi, YoumnaElsaid Abdulmotalib, HebaFuad Amous, TagreedSuliman Aljulban, Haifa Mohammed Al Aiban, Sali Mohamad Haffar
Annals of Dental Specialty.2023; 11(2): 124. CrossRef
Obturation canalaire
N. Linas, M.-L. Munoz-Sanchez, N. Decerle, P.-Y. Cousson
EMC - Médecine buccale.2023; 16(5): 1. CrossRef
Biodentine Inhibits the Initial Microbial Adhesion of Oral Microbiota In Vivo
Ali Al-Ahmad, Michael Haendel, Markus Altenburger, Lamprini Karygianni, Elmar Hellwig, Karl Wrbas, Kirstin Vach, Christian Tennert
Antibiotics.2022; 12(1): 4. CrossRef
Pilot Evaluation of Sealer-Based Root Canal Obturation Using Epoxy-Resin-Based and Calcium-Silicate-Based Sealers: A Randomized Clinical Trial
Minju Song, Min-Gyu Park, Sang-Won Kwak, Ruben H. Kim, Jung-Hong Ha, Hyeon-Cheol Kim
Materials.2022; 15(15): 5146. CrossRef
The antibacterial activity of mineral trioxide aggregate containing calcium fluoride
Miyoung Lim, Seunghoon Yoo
Journal of Dental Sciences.2022; 17(2): 836. CrossRef
Physicochemical and Mechanical Properties of Premixed Calcium Silicate and Resin Sealers
Naji Kharouf, Salvatore Sauro, Ammar Eid, Jihed Zghal, Hamdi Jmal, Anta Seck, Valentina Macaluso, Frédéric Addiego, Francesco Inchingolo, Christine Affolter-Zbaraszczuk, Florent Meyer, Youssef Haikel, Davide Mancino
Journal of Functional Biomaterials.2022; 14(1): 9. CrossRef
Comparison of Fracture Resistance between Single-cone and Warm Vertical Compaction Technique Using Bio-C Sealer® in Mandibular Incisors: An In Vitro Study
Raphael Lichaa, George Deeb, Rami Mhanna, Carla Zogheib
The Journal of Contemporary Dental Practice.2022; 23(2): 143. CrossRef
In vitro physicochemical characterization of five root canal sealers and their influence on an ex vivo oral multi‐species biofilm community
Flavia M. Saavedra, Lauter E. Pelepenko, William S. Boyle, Anqi Zhang, Christopher Staley, Mark C. Herzberg, Marina A. Marciano, Bruno P. Lima
International Endodontic Journal.2022; 55(7): 772. CrossRef
Premixed Calcium Silicate-Based Root Canal Sealer Reinforced with Bioactive Glass Nanoparticles to Improve Biological Properties
Min-Kyung Jung, So-Chung Park, Yu-Jin Kim, Jong-Tae Park, Jonathan C. Knowles, Jeong-Hui Park, Khandmaa Dashnyam, Soo-Kyung Jun, Hae-Hyoung Lee, Jung-Hwan Lee
Pharmaceutics.2022; 14(9): 1903. CrossRef
A critical analysis of research methods and experimental models to study root canal fillings
Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
International Endodontic Journal.2022; 55(S2): 384. CrossRef
Bioactivity Potential of Bioceramic-Based Root Canal Sealers: A Scoping Review
Mauro Schmitz Estivalet, Lucas Peixoto de Araújo, Felipe Immich, Adriana Fernandes da Silva, Nadia de Souza Ferreira, Wellington Luiz de Oliveira da Rosa, Evandro Piva
Life.2022; 12(11): 1853. CrossRef
The influence of humidity on bond strength of AH Plus, BioRoot RCS, and Nanoseal-S sealers
Sunanda Laxman Gaddalay, Damini Vilas Patil, Ramchandra Kabir
Endodontology.2022; 34(3): 202. CrossRef
The Effect of Bioceramic HiFlow and EndoSequence Bioceramic Sealers on Increasing the Fracture Resistance of Endodontically Treated Teeth: An In Vitro Study
Mohamad Khir Abdulsamad Alskaf, Hassan Achour, Hasan Alzoubi
Cureus.2022;[Epub] CrossRef
Unravelling the effects of ibuprofen-acetaminophen infused copper-bioglass towards the creation of root canal sealant
Chitra S, Riju Chandran, Ramya R, Durgalakshmi D, Balakumar S
Biomedical Materials.2022; 17(3): 035001. CrossRef
A Micro-CT Analysis of Initial and Long-Term Pores Volume and Porosity of Bioactive Endodontic Sealers
Mateusz Radwanski, Michal Leski, Adam K. Puszkarz, Jerzy Sokolowski, Louis Hardan, Rim Bourgi, Salvatore Sauro, Monika Lukomska-Szymanska
Biomedicines.2022; 10(10): 2403. CrossRef
A comprehensive in vitro comparison of the biological and physicochemical properties of bioactive root canal sealers
Sabina Noreen Wuersching, Christian Diegritz, Reinhard Hickel, Karin Christine Huth, Maximilian Kollmuss
Clinical Oral Investigations.2022; 26(10): 6209. CrossRef
Stability and solubility test of endodontic materials
Ivan Matovic, Jelena Vucetic
Stomatoloski glasnik Srbije.2022; 69(4): 169. CrossRef
Antimicrobial effectiveness of root canal sealers againstEnterococcus faecalis
Paola Castillo-Villagomez, Elizabeth Madla-Cruz, Fanny Lopez-Martinez, Idalia Rodriguez-Delgado, Jorge Jaime Flores-Treviño, Guadalupe Ismael Malagon-Santiago, Myriam Angelica de La Garza-Ramos
Biomaterial Investigations in Dentistry.2022; 9(1): 47. CrossRef
Tricalcium silicate cement sealers
Anita Aminoshariae, Carolyn Primus, James C. Kulild
The Journal of the American Dental Association.2022; 153(8): 750. CrossRef
Influence of variations in the environmental pH on the solubility and water sorption of a calcium silicate‐based root canal sealer
E. J. N. L. Silva, C. M. Ferreira, K. P. Pinto, A. F. A. Barbosa, M. V. Colaço, L. M. Sassone
International Endodontic Journal.2021; 54(8): 1394. CrossRef
Calcium Silicate-Based Root Canal Sealers: A Narrative Review and Clinical Perspectives
Germain Sfeir, Carla Zogheib, Shanon Patel, Thomas Giraud, Venkateshbabu Nagendrababu, Frédéric Bukiet
Materials.2021; 14(14): 3965. CrossRef
Development of A Nano-Apatite Based Composite Sealer for Endodontic Root Canal Filling
Angelica Bertacci, Daniele Moro, Gianfranco Ulian, Giovanni Valdrè
Journal of Composites Science.2021; 5(1): 30. CrossRef
Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae
Jessica Emanuella Rocha Paz, Priscila Oliveira Costa, Albert Alexandre Costa Souza, Ingrid Macedo de Oliveira, Lucas Fernandes Falcão, Carlos Alberto Monteiro Falcão, Maria Ângela Area Leão Ferraz, Lucielma Salmito Soares Pinto
Restorative Dentistry & Endodontics.2021;[Epub] CrossRef
Characterization, Antimicrobial Effects, and Cytocompatibility of a Root Canal Sealer Produced by Pozzolan Reaction between Calcium Hydroxide and Silica
Mi-Ah Kim, Vinicius Rosa, Prasanna Neelakantan, Yun-Chan Hwang, Kyung-San Min
Materials.2021; 14(11): 2863. CrossRef
Synthesis and Characterization of Novel Calcium-Silicate Nanobioceramics with Magnesium: Effect of Heat Treatment on Biological, Physical and Chemical Properties
Konstantina Kazeli, Ioannis Tsamesidis, Anna Theocharidou, Lamprini Malletzidou, Jonathan Rhoades, Georgia K. Pouroutzidou, Eleni Likotrafiti, Konstantinos Chrissafis, Theodoros Lialiaris, Lambrini Papadopoulou, Eleana Kontonasaki, Evgenia Lymperaki
Ceramics.2021; 4(4): 628. CrossRef
Calcium Silicate Cements vs. Epoxy Resin Based Cements: Narrative Review
Mario Dioguardi, Cristian Quarta, Diego Sovereto, Giuseppe Troiano, Khrystyna Zhurakivska, Maria Bizzoca, Lorenzo Lo Muzio, Lucio Lo Russo
Oral.2021; 1(1): 23. CrossRef
In Vitro Microleakage Evaluation of Bioceramic and Zinc-Eugenol Sealers with Two Obturation Techniques
Francesco De Angelis, Camillo D’Arcangelo, Matteo Buonvivere, Rachele Argentino, Mirco Vadini
Coatings.2021; 11(6): 727. CrossRef
Efficacy Of Calcium Silicate-Based Sealers In Root Canal Treatment: A Systematic Review
Hattan Mohammed Omar Baismail, Mohammed Ghazi Moiser Albalawi, Alaa Mofareh Thoilek Alanazi, Muhannad Atallah Saleem Alatawi, Badr Soliman Alhussain
Annals of Dental Specialty.2021; 9(1): 87. CrossRef
Apical Sealing Ability of Two Calcium Silicate-Based Sealers Using a Radioactive Isotope Method: An In Vitro Apexification Model
Inês Raquel Pereira, Catarina Carvalho, Siri Paulo, José Pedro Martinho, Ana Sofia Coelho, Anabela Baptista Paula, Carlos Miguel Marto, Eunice Carrilho, Maria Filomena Botelho, Ana Margarida Abrantes, Manuel Marques Ferreira
Materials.2021; 14(21): 6456. CrossRef

3,808 View
102 Download
81 Crossref

Research Articles

Calcium hydroxide intracanal medication effects on pain and flare-up: a systematic review and meta-analysis: Ahmed Mohamed Ibrahim, Siza Yacoub Zakhary, Suzan Abdul Wanees Amin; Restor Dent Endod 2020;45(3):e26. Published online May 22, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e26

Abstract PDF Supplementary Material PubReader ePub

Objectives

This study aimed to systematically review the pain and flare-up effects of calcium hydroxide (CH) as intracanal medication (ICM) in non-vital mature teeth.

Materials and Methods

Electronic-databases searching for published and grey literature and manual searching were conducted. Only randomized clinical trials (RCTs) were included comparing CH to other ICMs in non-vital mature teeth. The risk of bias was assessed using the RoB 2.0 Cochrane tool. The main outcomes were pain and flare-up. Qualitative and quantitative analysis, wherever applicable, was performed. The certainty of evidence (CoE) was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE).

Results

Sixteen articles were included in 6 comparisons at different time points for different outcomes. CH reduced pain risk than no ICM within the 1–14-days interval (p < 0.05) and than triple-antibiotic paste within the first day (p < 0.05) and was similar to corticosteroid/antibiotics combination (p > 0.05). Chlorhexidine (CHX) or CH/CHX, however, reduced pain levels than CH alone (p < 0.05). CH showed higher flare-up risk than CHX (p < 0.05). CoE, however, ranged from very low to moderate.

Conclusion

Most comparisons for different outcomes are based on very few studies, mostly low-powered, with an overall low CoE. Thus, the available evidence is considered insufficient to either support or refute CH effectiveness or to recommend one ICM over another. Therefore, further well-designed, larger RCTs are required.

Trial Registration

PROSPERO database Identifier: CRD42016041953

Citations

Citations to this article as recorded by

Garre’s osteomyelitis of the mandible managed by nonsurgical re-endodontic treatment
Heegyun Kim, Jiyoung Kwon, Hyun-Jung Kim, Soram Oh, Duck-Su Kim, Ji-Hyun Jang
Restorative Dentistry & Endodontics.2024;[Epub] CrossRef
Interpretation by literature review of the use of calcium hydroxide as an intra-ductal medication
María Belén Muñoz Padilla, Verónica Alicia Vega Martínez, Camila Alejandra Villafuerte Moya
Salud, Ciencia y Tecnología.2024; 4: 924. CrossRef
ProTaper Ultimate: The Evolution of Rotary Systems and Their Clinical Applicability
Mateo-Castillo JF, Siqueira-Sandrin VDS, Moreira RA, Brandelero Junior S, Olano-Dextre TL, Claudia R Pinheiro
Journal of Operative Dentistry & Endodontics.2024; 9(1): 16. CrossRef
Comparative Evaluation of Bacterial Reduction by Laser-Activated Irrigation Technique (LAI) With Conventional Needle Irrigation (CNI) in Single-Rooted Teeth With Pulpal Necrosis: A Single-Blinded Randomized Controlled Trial
Keerthika Rajamanickam, Sandhya Raghu, J Vijayashree Priyadharsini, Delphine Priscilla Antony, Nivedhitha Malli Sureshbabu
Cureus.2023;[Epub] CrossRef
Post-Operative Endodontic Pain Management: An Overview of Systematic Reviews on Post-Operatively Administered Oral Medications and Integrated Evidence-Based Clinical Recommendations
Federica Di Spirito, Giuseppe Scelza, Roberto Fornara, Francesco Giordano, Donato Rosa, Alessandra Amato
Healthcare.2022; 10(5): 760. CrossRef
Management of External Inflammatory Root Resorption following Tooth Autotransplantation Using a Modified Combination of Triple Antibiotics
Saeed Asgary, Ardavan Parhizkar, Paulo J. Palma
Case Reports in Dentistry.2022;[Epub] CrossRef
Calcium hydroxide as an intracanal medication for postoperative pain during primary root canal therapy: A systematic review and meta-analysis with trial sequential analysis of randomised controlled trials
Muhammad Zubair Ahmad, Durre Sadaf, Khalid A Merdad, Amani Almohaimeed, Igho J. Onakpoya
Journal of Evidence-Based Dental Practice.2022; 22(1): 101680. CrossRef
Post-operative Pain and Antibacterial Efficacy of Silver Nanoparticles Formulations Intracanal Medication: A Randomized Controlled Clinical Study
Nermine Hassan, Alaa Diab, Geraldine Ahmed
Open Access Macedonian Journal of Medical Sciences.2021; 9(D): 248. CrossRef

967 View
31 Download
8 Crossref

A micro-computed tomographic evaluation of root canal filling with a single gutta-percha cone and calcium silicate sealer: Jong Cheon Kim, Maung Maung Kyaw Moe, Sung Kyo Kim; Restor Dent Endod 2020;45(2):e18. Published online February 12, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e18

Abstract PDF PubReader ePub

Objectives

The purpose of this study was to evaluate the void of root canal filling over time when a calcium silicate sealer was used in the single gutta-percha cone technique.

Materials and Methods

Twenty-four J-shaped simulated root canals and twenty-four palatal root canals from extracted human maxillary molars were instrumented with ProFile Ni-Ti rotary instruments up to size 35/0.06 or size 40/0.06, respectively. Half of the canals were filled with Endoseal MTA and the other half were with AH Plus Jet using the single gutta-percha cone technique. Immediately after and 4 weeks after the root canal filling, the samples were scanned using micro-computed tomography at a resolution of 12.8 μm. The scanned images were reconstructed using the NRecon software and the void percentages were calculated using the CTan software, and statistically analyzed by 1-way analysis of variance, paired t-test and Tukey post hoc test.

Results

After 4 weeks, there were no significant changes in the void percentages at all levels in both material groups (p > 0.05), except at the apical level of the AH Plus Jet group (p < 0.05) in the simulated root canal showing more void percentage compared to other groups. Immediately after filling the extracted human root canals, the Endoseal MTA group showed significantly less void percentage compared to the AH Plus Jet group (p < 0.05).

Conclusions

Under the limitations of this study, the Endoseal MTA does not seem to reduce the voids over time.

Citations

Citations to this article as recorded by

Evaluation of various obturation techniques with bioceramic sealers in 3D-printed C-shaped canals
Maryam Gharechahi, Melika Hoseinzadeh, Saeed Moradi, Mina Mehrjouei
BMC Oral Health.2024;[Epub] CrossRef
Comparison of obturation quality in natural and replica teeth root-filled using different sealers and techniques
Chuta Kooanantkul, Richard M Shelton, Josette Camilleri
Clinical Oral Investigations.2023; 27(5): 2407. CrossRef
Obturation canalaire
N. Linas, M.-L. Munoz-Sanchez, N. Decerle, P.-Y. Cousson
EMC - Médecine buccale.2023; 16(5): 1. CrossRef
The Effect of Sealer Application Methods on Voids Volume after Aging of Three Calcium Silicate-Based Sealers: A Micro-Computed Tomography Study
Amre R. Atmeh, Rakan Alharbi, Ibrahim Aljamaan, Abdulrahman Alahmari, Ashwin C. Shetty, Ahmed Jamleh, Imran Farooq
Tomography.2022; 8(2): 778. CrossRef
Clinical Efficacy of Sealer-based Obturation Using Calcium Silicate Sealers: A Randomized Clinical Trial
Ji-hyung Kim, Sin-Yeon Cho, Yoonwoo Choi, Do-hyun Kim, Su-Jung Shin, Il-Young Jung
Journal of Endodontics.2022; 48(2): 144. CrossRef
A critical analysis of research methods and experimental models to study root canal fillings
Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
International Endodontic Journal.2022; 55(S2): 384. CrossRef
Calcium Silicate Cements vs. Epoxy Resin Based Cements: Narrative Review
Mario Dioguardi, Cristian Quarta, Diego Sovereto, Giuseppe Troiano, Khrystyna Zhurakivska, Maria Bizzoca, Lorenzo Lo Muzio, Lucio Lo Russo
Oral.2021; 1(1): 23. CrossRef
Physico-Chemical Properties of Calcium-Silicate vs. Resin Based Sealers—A Systematic Review and Meta-Analysis of Laboratory-Based Studies
Viresh Chopra, Graham Davis, Aylin Baysan
Materials.2021; 15(1): 229. CrossRef
Micro-computed tomography in preventive and restorative dental research: A review
Mehrsima Ghavami-Lahiji, Reza Tayefeh Davalloo, Gelareh Tajziehchi, Paria Shams
Imaging Science in Dentistry.2021; 51(4): 341. CrossRef
Main and Accessory Canal Filling Quality of a Premixed Calcium Silicate Endodontic Sealer According to Different Obturation Techniques
Su-Yeon Ko, Hae Won Choi, E-Deun Jeong, Vinicius Rosa, Yun-Chan Hwang, Mi-Kyung Yu, Kyung-San Min
Materials.2020; 13(19): 4389. CrossRef

498 View
5 Download
10 Crossref

A micro-computed tomography evaluation of voids using calcium silicate-based materials in teeth with simulated internal root resorption: Vildan Tek, Sevinç Aktemur Türker; Restor Dent Endod 2020;45(1):e5. Published online November 29, 2019; DOI: https://doi.org/10.5395/rde.2020.45.e5

Abstract PDF PubReader ePub

Objectives

The obturation quality of MTA, Biodentine, Total Fill BC root canal sealer (RCS), and warm gutta-percha (WGP) in teeth with simulated internal root resorption (IRR) was evaluated by using micro-computed tomography.

Materials and Methods

Standardized IRR cavities were created using 40 extracted maxillary central incisor teeth and randomly assigned into 4 groups (n = 10). IRR cavities were filled with MTA, Biodentine, Total Fill BC RCS (bulk-fill form) and WGP + Total Fill BC RCS. Percentage of voids between resorptive cavity walls and obturation material (external void), and inside the filling materials (internal voids) were measured.

Results

Total Fill BC sealer in the bulk-fill form presented significantly highest values of external and internal void percentages (p < 0.05). Biodentine showed a significantly lowest external void percentage (p < 0.05). WGP + Total Fill BC RCS presented significantly lower values of internal void percentages than all groups (p < 0.05), except Biodentine (p > 0.05).

Conclusion

None of the filling materials were created void-free obturation in resorption cavities. Biodentine may favor its application in teeth with IRR over Angelus MTA and bulk-fill form of Total Fill BC.

Citations

Citations to this article as recorded by

Evaluation of Different Techniques and Materials for Filling in 3-dimensional Printed Teeth Replicas with Perforating Internal Resorption by Means of Micro–Computed Tomography
Angelo J.S. Torres-Carrillo, Helena C. Assis, Rodrigo E. Salazar-Gamarra, Leonardo Moreira Teodosio, Alice C. Silva-Sousa, Jardel F. Mazzi-Chaves, Priscila B. Ferreira-Soares, Manoel D. Sousa-Neto, Fabiane C. Lopes-Olhê
Journal of Endodontics.2024; 50(2): 205. CrossRef
Three-Dimensional Measurement of Obturation Quality of Bioceramic Materials in Filling Artificial Internal Root Resorption Cavities Using Different Obturation Techniques: An In Vitro Comparative Study
Ammar M. Sharki, Ahmed H. Ali
Journal of Endodontics.2024; 50(7): 997. CrossRef
Evaluation of calcium hydroxide root canal filling materials by cone beam computed tomography and three-dimensional modeling
Asel Usdat Ozturk, Ekin Dogan, Venus Seyedoskuyi, Berk Senguler, Asli Topaloglu-Ak
Folia Medica.2024; 66(2): 250. CrossRef
Clinical applications of calcium silicate‐based materials: a narrative review
S Küçükkaya Eren
Australian Dental Journal.2023;[Epub] CrossRef
A critical analysis of research methods and experimental models to study root canal fillings
Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
International Endodontic Journal.2022; 55(S2): 384. CrossRef
An Updated Review on Properties and Indications of Calcium Silicate-Based Cements in Endodontic Therapy
Fateme Eskandari, Alireza Razavian, Rozhina Hamidi, Khadije Yousefi, Susan Borzou, Zohaib Khurshid
International Journal of Dentistry.2022; 2022: 1. CrossRef
Efficacy Of Calcium Silicate-Based Sealers In Root Canal Treatment: A Systematic Review
Hattan Mohammed Omar Baismail, Mohammed Ghazi Moiser Albalawi, Alaa Mofareh Thoilek Alanazi, Muhannad Atallah Saleem Alatawi, Badr Soliman Alhussain
Annals of Dental Specialty.2021; 9(1): 87. CrossRef

604 View
10 Download
7 Crossref

Bioactivity of endodontic biomaterials on dental pulp stem cells through dentin: Bahar Javid, Narges Panahandeh, Hassan Torabzadeh, Hamid Nazarian, Ardavan Parhizkar, Saeed Asgary; Restor Dent Endod 2020;45(1):e3. Published online November 4, 2019; DOI: https://doi.org/10.5395/rde.2020.45.e3

Abstract PDF PubReader ePub

Objectives

This study investigated the indirect effect of calcium-enriched mixture (CEM) cement and mineral trioxide aggregate (MTA), as 2 calcium silicate-based hydraulic cements, on human dental pulp stem cells (hDPSCs) through different dentin thicknesses.

Materials and Methods

Two-chamber setups were designed to simulate indirect pulp capping (IPC). Human molars were sectioned to obtain 0.1-, 0.3-, and 0.5-mm-thick dentin discs, which were placed between the 2 chambers to simulate an IPC procedure. Then, MTA and CEM were applied on one side of the discs, while hDPSCs were cultured on the other side. After 2 weeks of incubation, the cells were removed, and cell proliferation, morphology, and attachment to the discs were evaluated under scanning electron microscopy (SEM). Energy-dispersive X-ray (EDXA) spectroscopy was performed for elemental analysis. Alkaline phosphatase (ALP) activity was assessed quantitatively. The data were analyzed using the Kruskal-Wallis and Mann-Whitney tests.

Results

SEM micrographs revealed elongated cells, collagen fibers, and calcified nucleations in all samples. EDXA verified that the calcified nucleations consisted of calcium phosphate. The largest calcifications were seen in the 0.1-mm-thick dentin subgroups. There was no significant difference in ALP activity across the CEM subgroups; however, ALP activity was significantly lower in the 0.1-mm-thick dentin subgroup than in the other MTA subgroups (p < 0.05).

Conclusions

The employed capping biomaterials exerted biological activity on hDPSCs, as shown by cell proliferation, morphology, and attachment and calcific precipitations, through 0.1- to 0.5-mm-thick layers of dentin. In IPC, the bioactivity of these endodontic biomaterials is probably beneficial.

Citations

Citations to this article as recorded by

Effect of pulp capping materials on odontogenic differentiation of human dental pulp stem cells: An in vitro study
Mahmoud M. Bakr, Mohamed Shamel, Shereen N. Raafat, Robert M. Love, Mahmoud M. Al‐Ankily
Clinical and Experimental Dental Research.2024;[Epub] CrossRef
Effects of Growth Factors on the Differentiation of Dental Stem Cells: A Systematic Review and Meta-analysis (Part I)
Sayna Shamszadeh, Armin Shirvani, Hassan Torabzadeh, Saeed Asgary
Current Stem Cell Research & Therapy.2024; 19(4): 523. CrossRef
The Role of Growth Factor Delivery Systems on Cellular Activities of Dental Stem Cells: A Systematic Review (Part II)
Sayna Shamszadeh, Armin Shirvani, Saeed Asgary
Current Stem Cell Research & Therapy.2024; 19(4): 587. CrossRef
Comprehensive review of composition, properties, clinical applications, and future perspectives of calcium-enriched mixture (CEM) cement: a systematic analysis
Saeed Asgary, Mahtab Aram, Mahta Fazlyab
BioMedical Engineering OnLine.2024;[Epub] CrossRef
Evaluation of dental pulp stem cells behavior after odontogenic differentiation induction by three different bioactive materials on two different scaffolds
Basma Ahmed, Mai H. Ragab, Rania A. Galhom, Hayam Y. Hassan
BMC Oral Health.2023;[Epub] CrossRef
Characterization of Dental Pulp Stem Cell Responses to Functional Biomaterials Including Mineralized Trioxide Aggregates
Sejin Bae, Bueonguk Kang, Hyungbin Lee, Harrison Luu, Eric Mullins, Karl Kingsley
Journal of Functional Biomaterials.2021; 12(1): 15. CrossRef
Incorporation of amoxicillin-loaded microspheres in mineral trioxide aggregate cement: an in vitro study
Fábio Rocha Bohns, Vicente Castelo Branco Leitune, Isadora Martini Garcia, Bruna Genari, Nélio Bairros Dornelles, Silvia Stanisçuaski Guterres, Fabrício Aulo Ogliari, Mary Anne Sampaio de Melo, Fabrício Mezzomo Collares
Restorative Dentistry & Endodontics.2020;[Epub] CrossRef

399 View
7 Download
7 Crossref

Review Article

Effect of calcium hydroxide on inflammatory root resorption and ankylosis in replanted teeth compared with other intracanal materials: a review: Maryam Zare Jahromi, Mahmood Reza Kalantar Motamedi; Restor Dent Endod 2019;44(3):e32. Published online August 1, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e32

Abstract PDF PubReader ePub

Calcium hydroxide (CH) is the gold-standard intracanal dressing for teeth subjected to traumatic avulsion. A common complication after the replantation of avulsed teeth is root resorption (RR). The current review was conducted to compare the effect of CH with that of other intracanal medications and filling materials on inflammatory RR and replacement RR (ankylosis) in replanted teeth. The PubMed and Scopus databases were searched through June 2018 using specific keywords related to the title of the present article. The materials that were compared to CH were in 2 categories: 1) mineral trioxide aggregate (MTA) and endodontic sealers as permanent filling materials for single-visit treatment, and 2) Ledermix, bisphosphonates, acetazolamide, indomethacin, gallium nitrate, and enamel matrix-derived protein (Emdogain) as intracanal medicaments for multiple-visit management of avulsed teeth prior to the final obturation. MTA can be used as a single-visit root filling material; however, there are limited data on its efficacy due to a lack of clinical trials. Ledermix and acetazolamide were comparable to CH in reducing RR. Emdogain seems to be an interesting material, but the data supporting its use as an intracanal medication remain very limited. The conclusions drawn in this study were limited by the insufficiency of clinical trials.

Citations

Citations to this article as recorded by

Efficacy of Simvastatin in Inhibiting Bone Resorption and Promoting Healing in Delayed Tooth Avulsion: A Case Series
Rajesh Kumar, Supraja N Atluri, Alekhya Achanta, Chittaranjan Bogishetty, Tejaswini R Chunduri, Tejaswini PSS, Ramakrishna Ravi
Cureus.2025;[Epub] CrossRef
Bioactive potential of Bio-C Temp demonstrated by systemic mineralization markers and immunoexpression of bone proteins in the rat connective tissue
Camila Soares Lopes, Mateus Machado Delfino, Mário Tanomaru-Filho, Estela Sasso-Cerri, Juliane Maria Guerreiro-Tanomaru, Paulo Sérgio Cerri
Journal of Materials Science: Materials in Medicine.2024;[Epub] CrossRef
The use of mineral trioxide aggregate for treatment of children with complications of dental trauma
L.Yu. Kharkova, M.V. Korolenkova
Stomatology.2024; 103(4): 59. CrossRef
Instant Re-Implantation of Avulsed Teeth
Smita Paul, Sambarta Das, Nirmal Debbarma, Barun Dasgupta, Bidyut Seal, Ayesha Satapathy
Journal of Pharmacy and Bioallied Sciences.2024; 16(Suppl 4): S3461. CrossRef
Interpretation by literature review of the use of calcium hydroxide as an intra-ductal medication
María Belén Muñoz Padilla, Verónica Alicia Vega Martínez, Camila Alejandra Villafuerte Moya
Salud, Ciencia y Tecnología.2024; 4: 924. CrossRef
Evaluation of the physicochemical properties of intracanal medications used in traumatized teeth
Patricia Almeida da Silva de Macedo, Walbert de Andrade Vieira, Paulo Henrique Gabriel, Karla de Faria Vasconcelos, Francisco Haiter Neto, Ana Carolina Correia Laurindo de Cerqueira Neto, Brenda Paula Figueiredo de Almeida Gomes, Marcos Roberto dos Santo
Brazilian Journal of Oral Sciences.2024; 23: e242997. CrossRef
Treatment of Teeth with Root Resorptions: A Case Report and Systematic Review
Damla Erkal, Abdullah Başoğlu, Damla Kırıcı, Nezahat Arzu Kayar, Simay Koç, Kürşat Er
Galician Medical Journal.2023;[Epub] CrossRef
Successful outcome of permanent maxillary incisor reimplanted after 30 hours of extra‐oral time—a case report with 5‐year follow‐up
Ibadat Preet Kaur, Ashok Kumar, Mukul Kumar, Kanistika Jha
Clinical Case Reports.2023;[Epub] CrossRef
Replantation of an Avulsed Tooth: A Case Report
Nishad Kadulkar, Rubi Kataki, Adrija Deka, Salouno Thonai
Cureus.2023;[Epub] CrossRef
Avulsion of Permanent Mandibular Incisors: A Report of Two Cases with Pertinent Literature
Ibadat Preet Kaur, Jitendra Sharan, Pallawi Sinha, Ashok Kumar, Anand Marya, Leandro Napier de Souza
Case Reports in Dentistry.2023; 2023: 1. CrossRef
The Impact of Autologous Platelet Concentrates on the Periapical Tissues and Root Development of Replanted Teeth: A Systematic Review
Zohaib Khurshid, Faris Yahya I. Asiri, Shariq Najeeb, Jithendra Ratnayake
Materials.2022; 15(8): 2776. CrossRef

840 View
22 Download
11 Crossref

Case Report

Surgical management of an accessory canal in a maxillary premolar: a case report: Hee-Jin Kim, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min; Restor Dent Endod 2019;44(3):e30. Published online July 29, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e30

Abstract PDF PubReader ePub

We report the surgical endodontic treatment of a maxillary first premolar with a lateral lesion that originated from an accessory canal. Although lesions originating from accessory canals frequently heal with simple conventional endodontic therapy, some lesions may need additional and different treatment. In the present case, conventional root canal retreatment led to incomplete healing with the need for further treatment (i.e., surgery). Surgical endodontic management with a fast-setting calcium silicate cement was performed on the accessory canal using a dental operating microscope. At the patient's 9-month recall visit, the lesion was resolved upon radiography.

Citations

Citations to this article as recorded by

Predictive analysis of root canal morphology in relation to root canal treatment failures: a retrospective study
Mohmed Isaqali Karobari, Vishnu Priya Veeraraghavan, P. J. Nagarathna, Sudhir Rama Varma, Jayaraj Kodangattil Narayanan, Santosh R. Patil
Frontiers in Dental Medicine.2025;[Epub] CrossRef
Endodontic management of internal replacement resorption of two maxillary central incisors with the aid of cone-beam computed tomography as the diagnostic tool: a case report and review of literature
Fatemeh Eskandari, Safoora Sahebi, Negar Ghorbani Jahandizi, Hossein Mofidi
Journal of Medical Case Reports.2025;[Epub] CrossRef
The Impact of the Preferred Reporting Items for Case Reports in Endodontics (PRICE) 2020 Guidelines on the Reporting of Endodontic Case Reports
Sofian Youssef, Phillip Tomson, Amir Reza Akbari, Natalie Archer, Fayjel Shah, Jasmeet Heran, Sunmeet Kandhari, Sandeep Pai, Shivakar Mehrotra, Joanna M Batt
Cureus.2023;[Epub] CrossRef
Main and Accessory Canal Filling Quality of a Premixed Calcium Silicate Endodontic Sealer According to Different Obturation Techniques
Su-Yeon Ko, Hae Won Choi, E-Deun Jeong, Vinicius Rosa, Yun-Chan Hwang, Mi-Kyung Yu, Kyung-San Min
Materials.2020; 13(19): 4389. CrossRef

374 View
5 Download
4 Crossref

Research Articles

Coronal tooth discoloration induced by regenerative endodontic treatment using different scaffolds and intracanal coronal barriers: a 6-month ex vivo study: Noushin Shokouhinejad, Hassan Razmi, Maryam Farbod, Marzieh Alikhasi, Josette Camilleri; Restor Dent Endod 2019;44(3):e25. Published online July 16, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e25

Abstract PDF PubReader ePub

Objective

The aim of this study was to evaluate discoloration of teeth undergoing regenerative endodontic procedures (REPs) using blood clot or platelet-rich fibrin (PRF) as the scaffolds and different calcium silicate-based materials as the intracanal coronal barriers in an ex vivo model.

Materials and Methods

Forty-eight bovine incisors were prepared and disinfected using 1 mg/mL double antibiotic paste (DAP). The specimens were then randomly divided into 2 groups (n = 24) according to the scaffolds (blood or PRF). After placement of scaffolds each group was divided into 2 subgroups (n = 12) according to the intracanal coronal barriers (ProRoot MTA or Biodentine). The pulp chamber walls were sealed with dentin bonding agent before placement of DAP and before placement of scaffolds. The color changes (∆E) were measured at different steps. The data were analyzed using 2-way analysis of variance.

Results

Coronal discoloration induced by DAP was not clinically perceptible (ΔE ≤ 3.3). Regarding the type of the scaffold, coronal discoloration was significantly higher in blood groups compared with PRF groups at the end of REP and after 1 month (p < 0.05). However, no significant difference was found between PRF and blood clot after 6 months (p > 0.05). Considering the type of intracanal coronal barrier, no significant difference existed between ProRoot MTA and Biodentine (p > 0.05).

Conclusions

With sealing the dentinal tubules of pulp chamber with a dentin bonding agent and application of DAP as an intracanal medicament, coronal color change of the teeth following the use of PRF and blood sealed with either ProRoot MTA or Biodentine was not different at 6-month follow-up.

Citations

Citations to this article as recorded by

Impact of Biodentine Placement on Fracture Resistance and its Influence on Discoloration with Different Scaffolds
Evren Sarıyılmaz, Öznur Sarıyılmaz, Burak Çarıkçıoğlu, Gülşah Uslu, Raif Alan
Journal of Endodontics.2025;[Epub] CrossRef
Effect of pH on the solubility and volumetric change of ready-to-use Bio-C Repair bioceramic material
Luana Raphael da SILVA, Jader Camilo PINTO, Juliane Maria GUERREIRO-TANOMARU, Mário TANOMARU-FILHO
Brazilian Oral Research.2024;[Epub] CrossRef
Efficacy of Potassium Iodide and Glutathione for Correlation of Dentin Discoloration Caused by Silver Diamine Fluoride
Mahsa Samani, Hamid Majzoub, Faramarz Zakavi, Ayyub Mojaddami
Cureus.2024;[Epub] CrossRef
Intracanal medicaments and coronal sealing materials influence on root fracture resistance and coronal discoloration: An in vitro study
Rasoul Sahebalam, Marzie Boskabady, Maryam Naghavi, Samira Dehghanitafti
Saudi Endodontic Journal.2024; 14(2): 199. CrossRef
Potential Crown Discoloration Induced by the Combination of Various Intracanal Medicaments and Scaffolds Applied in Regenerative Endodontic Therapy
NB Altun, A Turkyilmaz
Nigerian Journal of Clinical Practice.2024; 27(7): 897. CrossRef
Evaluation of the effectiveness of different treatment approaches in preventing coronal discoloration caused by regenerative endodontic treatment
Melis Oya Ateş, Zeliha Uğur Aydın
Clinical Oral Investigations.2023; 27(8): 4595. CrossRef
Evaluation of the Effectiveness of Laser-Assisted Bleaching of the Teeth Discolored due to Regenerative Endodontic Treatment
Noushin Shokouhinejad, Mehrfam Khoshkhounejad, Fatemeh Hamidzadeh, Murilo Baena Lopes
International Journal of Dentistry.2022; 2022: 1. CrossRef
Effectiveness of Teeth Whitening after Regenerative Endodontics Procedures: An In Vitro Study
Irini Fagogeni, Joanna Metlerska, Tomasz Falgowski, Maciej Górski, Mariusz Lipski, Alicja Nowicka
Journal of Clinical Medicine.2022; 11(23): 7016. CrossRef
Microstructure and color stability of calcium silicate-based dental materials exposed to blood or platelet-rich fibrin
Noushin Shokouhinejad, Ibrahim Abu Tahun, Shima Saber Tahan, Fatemeh Mohandes, Mohammad H. Nekoofar, Paul M. H. Dummer
Clinical Oral Investigations.2022; 27(3): 1193. CrossRef
Spectrophotometric analysis of internal bleaching of traumatized teeth with coronal discoloration following regenerative endodontic procedures
Jaqueline Lazzari, Walbert Vieira, Vanessa Pecorari, Brenda Paula Figueiredo de Almeida Gomes, José Flávio Affonso de Almeida, Adriana De-Jesus-Soares
Brazilian Journal of Oral Sciences.2021;[Epub] CrossRef
Biological parameters, discolouration and radiopacity of calcium silicate‐based materials in a simulated model of partial pulpotomy
Lilian Vieira Oliveira, Gabriela Leite de Souza, Gisele Rodrigues da Silva, Thamara Eduarda Alves Magalhães, Gabrielle Alves Nunes Freitas, Ana Paula Turrioni, Gabriella Lopes de Rezende Barbosa, Camilla Christian Gomes Moura
International Endodontic Journal.2021; 54(11): 2133. CrossRef
Effect of hydrogel-based antibiotic intracanal medicaments on crown discoloration
Rayan B. Yaghmoor, Jeffrey A. Platt, Kenneth J. Spolnik, Tien Min Gabriel Chu, Ghaeth H. Yassen
Restorative Dentistry & Endodontics.2021;[Epub] CrossRef
The effect of different calcium silicate-based pulp capping materials on tooth discoloration: an in vitro study
Ahmad S. Al-Hiyasat, Dana M. Ahmad, Yousef S. Khader
BMC Oral Health.2021;[Epub] CrossRef
Knowledge, attitudes, and practices of undergraduate students concerning Regenerative Endodontics
Ligia B. da Silva, Mariana Gabriel, Márcia M. Marques, Fernanda C. Carrer, Flávia Gonçalves, Giovanna Sarra, Giovanna L. Carvalho, Ana Armas-Vega, Maria S. Moreira
Minerva Stomatologica.2020;[Epub] CrossRef
Coronal Discoloration Related to Bioceramic and Mineral Trioxide Aggregate Coronal Barrier in Non-vital Mature Teeth Undergoing Regenerative Endodontic Procedures
Mazen Doumani, Mohammad Yaman Seirawan, Kinda Layous, Mohammad Kinan Seirawan
World Journal of Dentistry.2020; 11(1): 52. CrossRef

507 View
10 Download
15 Crossref

Effect of intracanal medications on the interfacial properties of reparative cements: Andrea Cardoso Pereira, Mariana Valerio Pallone, Marina Angélica Marciano, Karine Laura Cortellazzi, Marcos Frozoni, Brenda P. F. A. Gomes, José Flávio Affonso de Almeida, Adriana de Jesus Soares; Restor Dent Endod 2019;44(2):e21. Published online May 9, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e21

Abstract PDF PubReader ePub

Objectives

The purpose of the present study was to evaluate the effect of calcium hydroxide with 2% chlorhexidine gel (HCX) or distilled water (HCA) compared to triple antibiotic paste (TAP) on push-out bond strength and the cement/dentin interface in canals sealed with White MTA Angelus (WMTA) or Biodentine (BD).

Materials and Methods

A total of 70 extracted human lower premolars were endodontically prepared and randomly divided into 4 groups according to the intracanal medication, as follows: group 1, HCX; group 2, TAP; group 3, HCA; and group 4, control (without intracanal medication). After 7 days, the medications were removed and the cervical third of the specimens was sectioned into five 1-mm sections. The sections were then sealed with WMTA or BD as a reparative material. After 7 days in 100% humidity, a push-out bond strength test was performed. Elemental analysis was performed at the interface, using energy-dispersive spectroscopy. The data were statistically analyzed using analysis of variance and the Tukey test (p < 0.05).

Results

BD presented a higher bond strength than WMTA (p < 0.05). BD or WMTA in canals treated with calcium hydroxide intracanal medications had the highest bond strength values, with a statistically significant difference compared to TAP in the WMTA group (p < 0.05). There were small amounts of phosphorus in samples exposed to triple antibiotic paste, regardless of the coronal sealing.

Conclusions

The use of intracanal medications did not affect the bond strength of WMTA and BD, except when TAP was used with WMTA.

Citations

Citations to this article as recorded by

Endodontic treatment of teeth with a wide apical opening – a clinical case
V. A. Popov, E. S. Pestova, S. A. Anisimova
Endodontics Today.2025; 23(2): 282. CrossRef
Effects of calcium hydroxide intracanal medicament on push‐out bond strength of endodontic sealers: A systematic review and meta‐analysis
Mohammed Nasser Alhajj, Fadhilah Daud, Sadeq Ali Al‐Maweri, Yanti Johari, Zuryati Ab‐Ghani, Mariatti Jaafar, Yoshihito Naito, Widyasri Prananingrum, Zaihan Ariffin
Journal of Esthetic and Restorative Dentistry.2022; 34(8): 1166. CrossRef
Evaluation of a Novel Tool for Apical Plug Formation during Apexification of Immature Teeth
Yasser Alsayed Tolibah, Line Droubi, Saleh Alkurdi, Mohammad Tamer Abbara, Nada Bshara, Thuraya Lazkani, Chaza Kouchaji, Ibrahim Ali Ahmad, Ziad D. Baghdadi
International Journal of Environmental Research and Public Health.2022; 19(9): 5304. CrossRef
Spectrophotometric analysis of internal bleaching of traumatized teeth with coronal discoloration following regenerative endodontic procedures
Jaqueline Lazzari, Walbert Vieira, Vanessa Pecorari, Brenda Paula Figueiredo de Almeida Gomes, José Flávio Affonso de Almeida, Adriana De-Jesus-Soares
Brazilian Journal of Oral Sciences.2021;[Epub] CrossRef
Do intracanal medications used in regenerative endodontics affect the bond strength of powder-to-liquid and ready-to-use cervical sealing materials?
MarinaCarvalho Prado, Kevillin Martiniano, AndreaCardoso Pereira, KarineL Cortellazzi, MarinaA Marciano, Gabriel Abuna, Adriana de-Jesus-Soares
Journal of Conservative Dentistry.2021; 24(5): 464. CrossRef

407 View
8 Download
5 Crossref

Discoloration of teeth due to different intracanal medicaments: Farzaneh Afkhami, Sadaf Elahy, Alireza Mahmoudi Nahavandi, Mohamad Javad Kharazifard, Aidin Sooratgar; Restor Dent Endod 2019;44(1):e10. Published online February 12, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e10

Abstract PDF PubReader ePub

Objectives

The objective of this study was to assess coronal discoloration induced by the following intracanal medicaments: calcium hydroxide (CH), a mixture of CH paste and chlorhexidine gel (CH/CHX), and triple antibiotic paste (3Mix).

Materials and Methods

Seventy extracted single-canal teeth were selected. Access cavities were prepared and each canal was instrumented with a rotary ProTaper system. The specimens were randomly assigned to CH, CH/CHX, and 3Mix paste experimental groups (n = 20 each) or a control group (n = 10). Each experimental group was randomly divided into 2 subgroups (A and B). In subgroup A, medicaments were only applied to the root canals, while in subgroup B, the root canals were completely filled with medicaments and a cotton pellet dipped in medicament was also placed in the pulp chamber. Spectrophotometric readings were obtained from the mid-buccal surface of the tooth crowns immediately after placing the medicaments (T1) and at 1 week (T2), 1 month (T3), and 3 months (T4) after filling. The ∆E was then calculated. Data were analyzed using 2-way analysis of variance (ANOVA), 3-way ANOVA, and the Scheffé post hoc test.

Results

The greatest color change (ΔE) was observed at 3 months (p < 0.0001) and in 3Mix subgroup B (p = 0.0057). No significant color change occurred in the CH (p = 0.7865) or CH/CHX (p = 0.1367) groups over time, but the 3Mix group showed a significant ΔE (p = 0.0164).

Conclusion

Intracanal medicaments may induce tooth discoloration. Use of 3Mix must be short and it must be carefully applied only to the root canals; the access cavity should be thoroughly cleaned afterwards.

Citations

Citations to this article as recorded by

Effects of Intra-canal Medicaments on Infrared Light Energy Transmission Through Enamel and Dentin During Photobiomodulation: An In Vitro Study
Sachin Kulkarni, Laurence J. Walsh, Yash Bhurani, Roy George
Journal of Endodontics.2025; 51(5): 616. CrossRef
Tooth discoloration caused by nanographene oxide as an irrigant and intracanal medicament in the endodontic treatment of extracted single-rooted teeth: An ex-vivo study
Abbas Abbaszadegan, Zeinab Rafiee, Bahar Asheghi, Ahmad Gholami, Mohmed Isaqali Karobari
PLOS One.2025; 20(6): e0325430. CrossRef
Effect of Calcium Hydroxide Versus Double Antibiotic Paste on Endodontic Treatment Outcomes in Teeth With Large Periapical Lesions: A Triple‐Blind Randomized Clinical Trial
Afsaneh Rahmati, Farshad Seyedein, Omid Dianat, Sara Saedi, Golriz Rostami, Alireza Akbarzadeh Baghban, Shima Sabertahan, Majid Kazem, Kee Y. Kum
International Journal of Dentistry.2024;[Epub] CrossRef
The effect of different intracanal irrigants on the push-out bond strength of dentin in damaged anterior primary teeth
Leila Bassir, Shirin Taravati, Farzad Nouri, Saeide Rahimi
Journal of Medicine and Life.2024; 17(5): 536. CrossRef
In Vıtro Evaluatıon of Dıscoloratıon Caused by Root Canal Sealers and Color Changes after Bleachıng
Emre Bodrumlu, Esma Dinger
Annals of Dental Specialty.2024; 12(1): 77. CrossRef
Assessment of Discoloration Induced by Root Canal Sealers and Color Alterations Post-Bleaching
T.P. Van der Burgt, T.P. Mullaney, A.J.M. Plasschaert
International Journal of Dental Research and Allied Sciences.2024; 4(1): 1. CrossRef
The effect of four different intracanal medicaments on the push-out bond strength of root canal sealers
Shalu Maan, Vijaya Dhar Bhatt, Rohit Singh, Sayak Gupta, Syed Alay Noorain, Aashna Gill, Pradeep Kumar, Sushil Yadav, Preeti Sharma
Journal of Medicine and Life.2022; 15(4): 448. CrossRef
Effect of hydrogel-based antibiotic intracanal medicaments on crown discoloration
Rayan B. Yaghmoor, Jeffrey A. Platt, Kenneth J. Spolnik, Tien Min Gabriel Chu, Ghaeth H. Yassen
Restorative Dentistry & Endodontics.2021;[Epub] CrossRef

544 View
16 Download
8 Crossref

Effects of the exposure site on histological pulpal responses after direct capping with 2 calcium-silicate based cements in a rat model: Panruethai Trongkij, Supachai Sutimuntanakul, Puangwan Lapthanasupkul, Chitpol Chaimanakarn, Rebecca Wong, Danuchit Banomyong; Restor Dent Endod 2018;43(4):e36. Published online August 22, 2018; DOI: https://doi.org/10.5395/rde.2018.43.e36

Abstract PDF PubReader ePub

Objectives

Direct pulp capping is a treatment for mechanically exposed pulp in which a biocompatible capping material is used to preserve pulpal vitality. Biocompatibility tests in animal studies have used a variety of experimental protocols, particularly with regard to the exposure site. In this study, pulp exposure on the occlusal and mesial surfaces of molar teeth was investigated in a rat model.

Materials and Methods

A total of 58 maxillary first molars of Wistar rats were used. Forty molars were mechanically exposed and randomly assigned according to 3 factors: 1) the exposure site (occlusal or mesial), 2) the pulp-capping material (ProRoot White MTA or Bio-MA), and 3) 2 follow-up periods (1 day or 7 days) (n = 5 each). The pulp of 6 intact molars served as negative controls. The pulp of 12 molars was exposed without a capping material (n = 3 per exposure site for each period) and served as positive controls. Inflammatory cell infiltration and reparative dentin formation were histologically evaluated at 1 and 7 days using grading scores.

Results

At 1 day, localized mild inflammation was detected in most teeth in all experimental groups. At 7 days, continuous/discontinuous calcified bridges were formed at exposure sites with no or few inflammatory cells. No significant differences in pulpal response according to the exposure site or calcium-silicate cement were observed.

Conclusions

The location of the exposure site had no effect on rat pulpal healing. However, mesial exposures could be performed easily, with more consistent results. The pulpal responses were not significantly different between the 2 capping materials.

Citations

Citations to this article as recorded by

The road map to proper dental pulp experiments in animal models
Nuha A Elmubarak
International Dental Journal of Student's Research.2024; 11(4): 163. CrossRef
Treatment outcomes of root perforations repaired by calcium silicate-based cements with or without an accelerator: A randomized controlled trial
Kanyarat Tungputsa, Danuchit Banomyong, Sittichoke Osiri, Supachai Sutimuntanakul
Endodontology.2024; 36(4): 315. CrossRef
Biological evaluation of novel phosphorylated pullulan‐based calcium hydroxide formulations as direct pulp capping materials: An in vivo study on a rat model
Md Refat Readul Islam, Rafiqul Islam, Yunqing Liu, Yu Toida, Yasuhiro Yoshida, Hidehiko Sano, Hany Mohamed Aly Ahmed, Atsushi Tomokiyo
International Endodontic Journal.2024; 57(9): 1247. CrossRef
3D-printed microgels supplemented with dentin matrix molecules as a novel biomaterial for direct pulp capping
Diana Cunha, Nayara Souza, Manuela Moreira, Nara Rodrigues, Paulo Silva, Cristiane Franca, Sivaporn Horsophonphong, Ashley Sercia, Ramesh Subbiah, Anthony Tahayeri, Jack Ferracane, Pamela Yelick, Vicente Saboia, Luiz Bertassoni
Clinical Oral Investigations.2022; 27(3): 1215. CrossRef
Calcium silicate and calcium aluminate cements for dentistry reviewed
Carolyn Primus, James L. Gutmann, Franklin R. Tay, Anna B. Fuks
Journal of the American Ceramic Society.2022; 105(3): 1841. CrossRef
Pulpal response to mineral trioxide aggregate containing phosphorylated pullulan-based capping material
Yu TOIDA, Shimpei KAWANO, Rafiqul ISLAM, Fu JIALE, AFM A CHOWDHURY, Shuhei HOSHIKA, Yasushi SHIMADA, Junji TAGAMI, Masahiro YOSHIYAMA, Satoshi INOUE, Ricardo M. CARVALHO, Yasuhiro YOSHIDA, Hidehiko SANO
Dental Materials Journal.2022; 41(1): 126. CrossRef
The Effect of Calcium-Silicate Cements on Reparative Dentinogenesis Following Direct Pulp Capping on Animal Models
Mihai Andrei, Raluca Paula Vacaru, Anca Coricovac, Radu Ilinca, Andreea Cristiana Didilescu, Ioana Demetrescu
Molecules.2021; 26(9): 2725. CrossRef
Histological evaluation of a novel phosphorylated pullulan‐based pulp capping material: An in vivo study on rat molars
Rafiqul Islam, Yu Toida, Fei Chen, Toru Tanaka, Satoshi Inoue, Tetsuya Kitamura, Yasuhiro Yoshida, Abu Faem Mohammad Almas Chowdhury, Hany Mohamed Aly Ahmed, Hidehiko Sano
International Endodontic Journal.2021; 54(10): 1902. CrossRef
Effectiveness of Direct Pulp Capping Bioactive Materials in Dentin Regeneration: A Systematic Review
Ermin Nie, Jiali Yu, Rui Jiang, Xiangzhen Liu, Xiang Li, Rafiqul Islam, Mohammad Khursheed Alam
Materials.2021; 14(22): 6811. CrossRef
A strontium and amorphous calcium phosphate dipped premixed injectable calcium silicate-based ceramic for dental root canal sealing
Huimin Jin, Yuzhu Li, Qingqing Wang, Menglu Dong, Mengmeng Yang, Wendy Chen, Shengrui Wang, Heng Zhang, Shunli Zheng, Chris Ying Cao, Zheng Zhou, Quan-Li Li
Ceramics International.2021; 47(23): 33738. CrossRef
Bioactive tri/dicalcium silicate cements for treatment of pulpal and periapical tissues
Carolyn M. Primus, Franklin R. Tay, Li-na Niu
Acta Biomaterialia.2019; 96: 35. CrossRef

516 View
6 Download
11 Crossref

Retention of BioAggregate and MTA as coronal plugs after intracanal medication for regenerative endodontic procedures: an ex vivo study: Suzan Abdul Wanees Amin, Shaimaa Ismail Gawdat; Restor Dent Endod 2018;43(3):e18. Published online April 26, 2018; DOI: https://doi.org/10.5395/rde.2018.43.e18

Abstract PDF PubReader ePub

Objectives

This study compared the retention of BioAggregate (BA; Innovative BioCeramix) and mineral trioxide aggregate (MTA; Angelus) as coronal plugs after applying different intracanal medications (ICMs) used in regenerative endodontics.

Materials and Methods

One-hundred human maxillary central incisors were used. The canals were enlarged to a diameter of 1.7 mm. Specimens were divided into 5 groups (n = 20) according to the ICM used: calcium hydroxide (CH), 2% chlorhexidine (CHX), triple-antibiotic paste (TAP), double-antibiotic paste (DAP), and no ICM (control; CON). After 3 weeks of application, ICMs were removed and BA or MTA were placed as the plug material (n = 10). The push-out bond strength and the mode of failure were assessed. The data were analyzed using 2-way analysis of variance, the Tukey's test, and the χ² test; p values < 0.05 indicated statistical significance.

Results

The type of ICM and the type of plug material significantly affected bond strength (p < 0.01). Regardless of the type of ICM, BA showed a lower bond strength than MTA (p < 0.05). For MTA, CH showed a higher bond strength than CON, TAP and DAP; CHX showed a higher bond strength than DAP (p < 0.01). For BA, CH showed a higher bond strength than DAP (p < 0.05). The mode of failure was predominantly cohesive for BA (p < 0.05).

Conclusions

MTA may show better retention than BA. The mode of bond failure with BA can be predominantly cohesive. BA retention may be less affected by ICM type than MTA retention.

Citations

Citations to this article as recorded by

An in vitro comparative evaluation of the effect of three intracanal medicaments – chlorhexidine gel, triple antibiotic paste, and calcium hydroxide paste on the push-out bond strength of MTA Plus, Biodentine, and calcium-enriched mixture
Gouthami Datta, Ramya Raghu, Ashish Shetty, Gautham P Manjunath, Dishant Patel, Subhashini Rajasekhara
Endodontology.2023; 35(1): 60. CrossRef
Effects of calcium hydroxide intracanal medicament on push‐out bond strength of endodontic sealers: A systematic review and meta‐analysis
Mohammed Nasser Alhajj, Fadhilah Daud, Sadeq Ali Al‐Maweri, Yanti Johari, Zuryati Ab‐Ghani, Mariatti Jaafar, Yoshihito Naito, Widyasri Prananingrum, Zaihan Ariffin
Journal of Esthetic and Restorative Dentistry.2022; 34(8): 1166. CrossRef
A Breakthrough in the Era of Calcium Silicate-Based Cements: A Critical Review
Payal S Chaudhari, Manoj G Chandak, Akshay A Jaiswal, Nikhil P Mankar, Priyanka Paul
Cureus.2022;[Epub] CrossRef
Modern Medicaments for Endodontic Treatment in Children
Н.В. Шаковец, О.С. Романова
Стоматология. Эстетика. Инновации.2021; (4): 408. CrossRef
Do intracanal medications used in regenerative endodontics affect the bond strength of powder-to-liquid and ready-to-use cervical sealing materials?
MarinaCarvalho Prado, Kevillin Martiniano, AndreaCardoso Pereira, KarineL Cortellazzi, MarinaA Marciano, Gabriel Abuna, Adriana de-Jesus-Soares
Journal of Conservative Dentistry.2021; 24(5): 464. CrossRef
In vivo Biocompatibility and Bioactivity of Calcium Silicate-Based Bioceramics in Endodontics
Wencheng Song, Wei Sun, Lili Chen, Zhenglin Yuan
Frontiers in Bioengineering and Biotechnology.2020;[Epub] CrossRef
Effect of Hydrogel-Based Antibiotic Intracanal Medicaments on Push-Out Bond Strength
Rayan B. Yaghmoor, Jeffrey A. Platt, Kenneth J. Spolnik, Tien Min Gabriel Chu, Ghaeth H. Yassen
European Journal of Dentistry.2020; 14(04): 575. CrossRef
Regenerative Endodontic Procedures, Disinfectants and Outcomes: A Systematic Review
Adam S. Kharchi, Nara Tagiyeva-Milne, Shalini Kanagasingam
Primary Dental Journal.2020; 9(4): 65. CrossRef

412 View
4 Download
8 Crossref

Case Report

Periodontal healing following non-surgical repair of an old perforation with pocket formation and oral communication: Saeed Asgary, Prashant Verma, Ali Nosrat; Restor Dent Endod 2018;43(2):e17. Published online April 13, 2018; DOI: https://doi.org/10.5395/rde.2018.43.e17

Abstract PDF PubReader ePub

Iatrogenic perforations negatively impact the outcome of endodontic treatments. Studies on prognostic factors showed that perforations in the coronal third of the root with periodontal pocket formation have an unfavorable prognosis. A 36-year-old female was referred for endodontic evaluation of tooth #13 with a history of an iatrogenic perforation, happened 3 years ago. There was a sinus tract associated with perforation, 10 mm probing on the mesial and mesio-palatal, bleeding on probing, radiolucent lesion adjacent to the perforation and complete resorption of the interdental bone between teeth #13 and #12. After the treatment options were discussed, she chose to save the tooth. The tooth was accessed under rubber dam isolation, the perforation site was cleaned and disinfected using 0.5% sodium hypochlorite and sealed with calcium-enriched mixture cement. Eighteen months after treatment the tooth was functional and asymptomatic. The probing depths were normal without bleeding on probing. Radiographically, the interdental crestal bone formed between teeth #13 and #12. Despite all negative prognostic factors in this case (i.e., perforations in the coronal third, pocket formation, and radiolucent lesion), healing was unexpectedly achieved via non-surgical repair of the perforation. Further research on biological aspects of healing in the periodontium following iatrogenic perforations are recommended.

Citations

Citations to this article as recorded by

Managing Internal Inflammatory Root Resorption and Perforation of a Mandibular Primary Molar: A Case Report With 15 Months Follow‐Up
Mana Mowji, Motahareh Khosrojerdi
Clinical Case Reports.2025;[Epub] CrossRef
Nonsurgical Management of Furcation Defects Using Cervical Sealing With Calcium–Silicate Cements: A Clinical Case Series
Saeed Asgary, Shamimul Hasan
Case Reports in Medicine.2025;[Epub] CrossRef
Comprehensive review of composition, properties, clinical applications, and future perspectives of calcium-enriched mixture (CEM) cement: a systematic analysis
Saeed Asgary, Mahtab Aram, Mahta Fazlyab
BioMedical Engineering OnLine.2024;[Epub] CrossRef
External Cervical Resorption: A Volumetric Analysis on Evolution of Defects over Time
Ali Nosrat, Omid Dianat, Prashant Verma, Martin D. Levin, Jeffery B. Price, Anita Aminoshariae, Fabio Antonio Piola Rizzante
Journal of Endodontics.2023; 49(1): 36. CrossRef
Comparative evaluation of mineral trioxide aggregate, endoseal, and biodentine in furcation perforation repair
Udita Khare Baralay, Srinidhi Surya Raghavendra
Endodontology.2022; 34(1): 22. CrossRef
Calcium Silicate Cements Application in Lateral Root Perforation Repair: A Case Report with 16-Month Follow-Up
Juan G. Robledo, Pablo A. Rodríguez
Open Journal of Stomatology.2021; 11(08): 317. CrossRef
Vital Pulp Therapy as a Conservative Approach for Management of Invasive Cervical Root Resorption: A Case Series
Saeed Asgary, Mahdieh Nourzadeh, Prashant Verma, M. Lamar Hicks, Ali Nosrat
Journal of Endodontics.2019; 45(9): 1161. CrossRef

757 View
4 Download
7 Crossref

Research Articles

Removal efficacy and cytotoxicity of a calcium hydroxide paste using N-2-methyl-pyrrolidone as a vehicle: Myung-Jin Lim, Hyun-Jin Jang, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min; Restor Dent Endod 2017;42(4):290-300. Published online October 20, 2017; DOI: https://doi.org/10.5395/rde.2017.42.4.290

Abstract PDF PubReader ePub

Objectives

This study investigated the removal efficacy and cytotoxicity of a newly developed calcium hydroxide paste (cleaniCal, Maruchi) using N-2-methyl-pyrrolidone (NMP) as a vehicle in comparison with ApexCal (Ivoclar Vivadent) and Calcipex II (Nishika), which use different vehicles such as polyethylene glycol and propylene glycol, respectively.

Materials and Methods

Thirty maxillary premolars with oval-shaped canals were divided into 3 groups and the teeth were filled with one of the pastes. After removal of the paste, micro-computed tomographic (μ-CT) imaging was obtained to assess the volume of residual paste in the root canal of each tooth. The teeth were then split longitudinally and the area of the paste-coated surface was evaluated by stereomicroscopy. The cytotoxicity of each product was assessed using an agar overlay assay. The effect of each vehicle on cell viability was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The data were analyzed using one-way analysis of variance and Tukey's tests to detect any significance (p < 0.05).

Results

In the μ-CT and stereomicroscopic analysis, cleaniCal exhibited less remnants of medicament than ApexCal and Calcipex. cleaniCal showed a higher cytotoxicity than the other pastes in the agar overlay assay. Furthermore, NMP exhibited lower cell viability compared to the other vehicles.

Conclusions

cleaniCal showed better removal efficacy compared to the other products. However, clinicians should be aware of the higher cytotoxicity of the NMP-based material and consider its possible adverse effects on periradicular tissue when it is overfilled.

Citations

Citations to this article as recorded by

Synergistic effects of reduced graphene oxide on the antibacterial activity of calcium hydroxide-based intracanal medicaments containing different vehicles
Mi-Ah Kim, Min-Kyeong Kim, Eun-Sook Kang, Kyung-San Min
Journal of Oral Science.2025; 67(1): 35. CrossRef
Lipoteichoic Acid from Lacticaseibacillus rhamnosus GG as a Novel Intracanal Medicament Targeting Enterococcus faecalis Biofilm Formation
Ji-Young Yoon, Somin Park, Dongwook Lee, Ok-Jin Park, WooCheol Lee, Seung Hyun Han
Journal of Microbiology.2024; 62(10): 897. CrossRef
Rheological properties and handling characteristics of four injectable calcium hydroxide pastes
Min-Jung KIM, In-Bog LEE
Dental Materials Journal.2024; 43(6): 796. CrossRef
Role of vehicles on antimicrobial efficacy of calcium hydroxide
Dikshya Purohit, Shronika, Pradyumna Misra, Gaurav Jain, Preeti Shukla
Asian Journal of Oral Health and Allied Sciences.2023; 13: 9. CrossRef
Removal of Calcium Hydroxide Paste Leaked Into the Maxillary Sinus
Dohee Kim, Young Kim, Jeong Joon Han
Ear, Nose & Throat Journal.2023;[Epub] CrossRef
Conservative Management of Molar Incisor Hypomineralization Using Biomimetic Material in a 9-Year-Old Boy
Sahili Mungekar-Markandey, Ashwin Jawdekar
Journal of Dental Research and Review.2022; 9(4): 320. CrossRef
Sonic irrigation for removal of calcium hydroxide in the apical root canal: A micro-CT and light-coupled tracking analysis
Wonjoon Moon, Shin Hye Chung, Juhea Chang, Zhaoqiang Zhang
PLOS ONE.2022; 17(6): e0268791. CrossRef
Effect of N-2-methyl-pyrrolidone on Enterococcus faecalis biofilms
Mi-Ah KIM, Prasanna NEELAKANTAN, Kyung-San MIN
Dental Materials Journal.2022; 41(5): 774. CrossRef
Characterization, Antimicrobial Effects, and Cytocompatibility of a Root Canal Sealer Produced by Pozzolan Reaction between Calcium Hydroxide and Silica
Mi-Ah Kim, Vinicius Rosa, Prasanna Neelakantan, Yun-Chan Hwang, Kyung-San Min
Materials.2021; 14(11): 2863. CrossRef
Synthesis, structure, and theoretical studies of a calcium complex of a unique dianion derived from 1-methylpyrrolidin-2-one
Ray J. Butcher, Andrew P. Purdy, Paul A. Brown, Daniel Gunlycke
Acta Crystallographica Section E Crystallographic Communications.2021; 77(1): 70. CrossRef
Effect of a calcium hydroxide-based intracanal medicament containing N-2-methyl pyrrolidone as a vehicle against Enterococcus faecalis biofilm
Taegun KIM, Mi-Ah KIM, Yun-Chan HWANG, Vinicius ROSA, Massimo DEL FABBRO, Kyung-San MIN
Journal of Applied Oral Science.2020;[Epub] CrossRef

585 View
4 Download
11 Crossref

White mineral trioxide aggregate mixed with calcium chloride dihydrate: chemical analysis and biological properties: Hany Mohamed Aly Ahmed, Norhayati Luddin, Thirumulu Ponnuraj Kannan, Khairani Idah Mokhtar, Azlina Ahmad; Restor Dent Endod 2017;42(3):176-187. Published online April 17, 2017; DOI: https://doi.org/10.5395/rde.2017.42.3.176

Abstract PDF PubReader ePub

Objectives

This study aimed to evaluate the chemical and biological properties of fast-set white mineral trioxide aggregate (FS WMTA), which was WMTA combined with calcium chloride dihydrate (CaCl₂·2H₂O), compared to that of WMTA.

Materials and Methods

Surface morphology, elemental, and phase analysis were examined using scanning electron microscope (SEM), energy dispersive X-ray microanalysis (EDX), and X-ray diffraction (XRD), respectively. The cytotoxicity and cell attachment properties were evaluated on human periodontal ligament fibroblasts (HPLFs) using methyl-thiazol-diphenyltetrazolium (MTT) assay and under SEM after 24 and 72 hours, respectively.

Results

Results showed that the addition of CaCl₂·2H₂O to WMTA affected the surface morphology and chemical composition. Although FS WMTA exhibited a non-cytotoxic profile, the cell viability values of this combination were lesser than WMTA, and the difference was significant in 7 out of 10 concentrations at the 2 time intervals (p < 0.05). HPLFs adhered over the surface of WMTA and at the interface, after 24 hours of incubation. After 72 hours, there were increased numbers of HPLFs with prominent cytoplasmic processes. Similar findings were observed with FS WMTA, but the cells were not as confluent as with WMTA.

Conclusions

The addition of CaCl₂·2H₂O to WMTA affected its chemical properties. The favorable biological profile of FS WMTA towards HPLFs may have a potential impact on its clinical application for repair of perforation defects.

Citations

Citations to this article as recorded by

The effect of three additives on properties of mineral trioxide aggregate cements: a systematic review and meta-analysis of in vitro studies
Behnam Bolhari, Faranak Noori, Hadi Assadian, Amir Raee, Sholeh Ghabraei, Ahmad-Reza Shamshiri, Artak Heboyan
BMC Oral Health.2024;[Epub] CrossRef
Evaluation of sorption and solubility of materials based on calcium aluminate
Renata Josipovic, Violeta Petrovic, Marijana Popovic-Bajic, Irena Kuzmanovic-Radman, Mirjana Umicevic-Davidovic, Aleksandra Djeri, Slavoljub Zivkovic
Stomatoloski glasnik Srbije.2023; 70(1): 26. CrossRef
Chitosan-Based Accelerated Portland Cement Promotes Dentinogenic/Osteogenic Differentiation and Mineralization Activity of SHED
Hasan Subhi, Adam Husein, Dasmawati Mohamad, Nik Rozainah Nik Abdul Ghani, Asma-Abdullah Nurul
Polymers.2021; 13(19): 3358. CrossRef
Chemical modification of MTA and CEM cement to decrease setting time and improve bioactivity properties by adding alkaline salts
Faeze Jamali Zavare, Hanieh Nojehdehian, Maryam Moezizadeh, Mehdi Daneshpooya
Journal of Dental Research, Dental Clinics, Dental Prospects.2020; 14(1): 1. CrossRef
Biological effects of acid-eroded MTA Repair HP and ProRoot MTA on human periodontal ligament stem cells
Mar Collado-González, Sergio López-García, David García-Bernal, Ricardo E. Oñate-Sánchez, Christopher J. Tomás-Catalá, Jose M. Moraleda, Adrián Lozano, Leopoldo Forner, Francisco J. Rodríguez-Lozano
Clinical Oral Investigations.2019; 23(10): 3915. CrossRef
Comparative Cytocompatibility and Mineralization Potential of Bio-C Sealer and TotalFill BC Sealer
Sergio López-García, Miguel R. Pecci-Lloret, Julia Guerrero-Gironés, María P. Pecci-Lloret, Adrián Lozano, Carmen Llena, Francisco Javier Rodríguez-Lozano, Leopoldo Forner
Materials.2019; 12(19): 3087. CrossRef
Evaluation of changes in ion release and biological properties of NeoMTA‐Plus and Endocem‐MTA exposed to an acidic environment
F. J. Rodríguez‐Lozano, M. Collado‐González, S. López‐García, D. García‐Bernal, J. M. Moraleda, A. Lozano, L. Forner, L. Murcia, R. E. Oñate‐Sánchez
International Endodontic Journal.2019; 52(8): 1196. CrossRef

510 View
4 Download
7 Crossref

Effect of three nanobiomaterials on microhardness of bleached enamel: Maryam Khoroushi, Farinaz Shirban, Sara Kaveh, Samaneh Doustfateme; Restor Dent Endod 2016;41(3):196-201. Published online July 14, 2016; DOI: https://doi.org/10.5395/rde.2016.41.3.196

Abstract PDF PubReader ePub

Objectives

The aim of this in vitro study was to evaluate the effect of incorporating three different nanobiomaterials into bleaching material on microhardness of bleached enamel.

Materials and Methods

The crowns of 24 extracted sound human molars were sectioned. Sixty enamel specimens (2 × 3 × 4 mm) were selected and divided into five groups (n = 12): Group 1 received no bleaching procedure (control); Group 2 underwent bleaching with a 40% hydrogen peroxide (HP) gel; Groups 3, 4, and 5 were bleached with a 40% HP gel modified by incorporation of bioactive glass (BAG), amorphous calcium phosphate (ACP) and hydroxyapatite (HA), respectively. The enamel microhardness was evaluated. The differences in Knoop microhardness data of each group were analyzed by one-way ANOVA, followed by post hoc Tukey tests.

Results

Significant differences were observed between the study groups. The enamel microhardness changes in Groups 1, 3, 4, and 5 were significantly lower than that of Group 2 (p < 0.001).

Conclusions

Within the limitations of this study, it can be concluded that incorporation of each one of the three tested biomaterials as remineralizing agents might be effective in decreasing enamel microhardness changes subsequent to in-office bleaching.

Citations

Citations to this article as recorded by

Protective role of calcium-based agents in dental bleaching gels: insights from a systematic review and meta-analysis of clinical and laboratory evidence
Gabriel Pereira Nunes, Renata de Oliveira Alves, Geórgia Rondó Peres, Matheus Henrique Faccioli Ragghianti, Priscila Toninatto Alves de Toledo, Alexandre Henrique dos Reis Prado, Carla Ferreira-Baptista, Alberto Carlos Botazzo Delbem
Clinical Oral Investigations.2025;[Epub] CrossRef
Analysis of Enamel Surface and Shear Bond Strength with Orthodontic Bracket at Different Time Intervals After Bleaching Treatment
Yu-Jin Lee, Ji-Yeon Hong, Hye-Min Ku, Song-Yi Yang
Journal of Dental Hygiene Science.2025; 25(2): 130. CrossRef
Effect of strontium fluorophosphate bioactive glass on color, microhardness and surface roughness of bleached enamel
Shiza Yezdani, Monisha Khatri, Sampath Vidhya, Sekar Mahalaxmi
Technology and Health Care.2024; 32(1): 285. CrossRef
In vitro evaluation of the effect of addition of biomaterials to carbamide peroxide on the bleaching efficacy and microhardness of enamel
Sowmya Kavoor, M. A. Ranjini, Naval Abdul Aziz, H. K. Ashok, Roopa R. Nadig
Journal of Conservative Dentistry and Endodontics.2024; 27(3): 310. CrossRef
Effect of hydrogen peroxide and its combination with nano-hydroxyapatite or nano-bioactive glass on the enamel demineralization and tooth color: An in vitro study
Elham Kheradmand, Alirea Daneshkazemi, Abdolrahim Davari, Maede Kave, Solmaz Ghanbarnejad
Dental Research Journal.2023;[Epub] CrossRef
Over‐the‐counter bleaching agents can help with tooth whitening maintenance
Olívia Santana Jorge, Carolina Noronha Ferraz de Arruda, Rafaella Tonani Torrieri, Rocio Geng Vivanco, Fernanda de Carvalho Panzeri Pires‐de‐Souza
Journal of Esthetic and Restorative Dentistry.2022; 34(2): 328. CrossRef
Effect of Indigenously Developed Nano-Hydroxyapatite Crystals from Chicken Egg Shell on the Surface Hardness of Bleached Human Enamel
Divya Kunam, Vidhya Sampath, Sujatha Manimaran, Mahalaxmi Sekar
Contemporary Clinical Dentistry.2019; 10(3): 489. CrossRef
Influence of Time Intervals between Bleaching Procedures on Enamel Microhardness and Surface Roughness
Roberta Pimentel de Oliveira, Juliana Costa Pereira Baia, Mara Eliane Soares Ribeiro, Mario Honorato da Silva e Souza Junior, Sandro Cordeiro Loretto
The Open Dentistry Journal.2018; 12(1): 555. CrossRef

393 View
3 Download
8 Crossref

First
Prev
Page of 2
Next
Last

Search